Part 2 Flashcards
High hydrogen —> stimulates peripheral chemoreceptors
—> increases respiratory rate —> blow off ______ = decrease hydrogen
CO2
The body produces fixed, metabolic, and nonvolatile acids that _______ be eliminated by respiration
Cannot
What removes fixed acids and generates bicarbonate?
Kidneys
What excretes titratable acids and ammonia?
Kidneys
What type of acids are urinary solutes that are filtered in base forms at glomeruli and bind secreted protons in the tubule fluid?
Titratable acids
What is the most important acid secreted by the kidneys?
Ammonia
What is the sum of urinary titratable acids plus urinary ammonia but NOT bicarbonate?
Renal net acid excretion
Plasma bicarbonate is ______ filtered
Freely
Where is all of the filtered bicarbonate reabsorbed?
Renal tubule epi cells
What do the kidneys secrete that binds to filtered buffers to generate urinary titratable acids?
Hydrogen ions
What is reabsorbed at PCT?
Filtered HCO3
What location for the regulation of H and HCO3 reabsorption is done by H ATPase, Na/H exchanger, Cl/HCO3 angiotensin 2, and PTH?
PT and TAL
What part is responsible for excreting urine with a pH extremely different from plasma?
CD
What the of epi cells are:
Large apical surface
Extensive membrane folds = micropliae
Type a or alpha cells
What the of epi cells are:
Small apical surface
Sparse microprojections
Type b or beta cells
