Part 2 Flashcards

1
Q

Antibodies are proteins secreted by ______ cells and are capable of binding to specific antigens

A

Plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Antibodies consist of four protein chains, two identical _____ and two ____ chains.

A

Heavy

Light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The variable region functions as the ______ _______ site where the constant region of the stem determines the _____ class

A

Antigen binding

class

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Antibody that attaches to the surface of cells

A

IgD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Antibody that is active in some allergies and parasitic infections

A

IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

First antibody released

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Antibody found in mucus and other secretions

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Antibody that crosses the placental barrier

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Antibody that works as a pentamer

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Antibody that helps prevent entry of pathogens in the body

A

IgA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

75-85% of antibodies in plasma

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Readily fixes and activates complement

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Potent agglutinating agent

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Functions as B cell receptor

A

IgD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Released in secondary and late primary response

A

IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Causes mast cells and basophils to release histamine

A

IgE

17
Q

This is a defense mechanism used by antibodies that block specifics sites on viruses

A

Neutralization

18
Q

This is a defense mechanism used by antibodies that causes them to bind the same determinant on more than one cell-bound antigen

A

Agglutination

19
Q

This is a defense mechanism used by antibodies that is when soluble molecules are cross-linked

A

Precipitation

20
Q

This is the main antibody defense against cellular antigens

A

Complete fixation and Activation

21
Q

In cell mediated immune response, ___ cells provide defense against intracellular antigens

A

T cells

22
Q

The two major types of T lymphocytes are ___ which turn into helper T cells and ___ that turn into cytoxic

A

CD4

CD8

23
Q

MHC Class I proteins are displayed by all cells except

A

RBCs

24
Q

MHC class II proteins are displayed by

A

APC

25
Q

What are the two steps of T cell activation?

A

Antigen binding and Co-simulation

26
Q

This is when cells bind to other surface receptors on an ACP

A

Co-Simulation

27
Q

______ cells play a central role in adaptive immune response

A

Helper T cells

28
Q

These T cells directly attack and kill other cells

A

Cytotoxic

29
Q

Where do autographs come from?

A

Body site of the same person

30
Q

Where do isografts come from?

A

Identical twin

31
Q

Where do allografts come from?

A

between individuals who arent identical

32
Q

Where do xenographs come from?

A

Another species

33
Q

These are congenital or acquired conditions that cause immune cells, phagocytes or complement to behave abnormally

A

Immunodeficiences

34
Q

This develops when the immune system losses the ability to distinguish self from nonself

A

Auto Immune

35
Q

This is the immune response to to a perceived threat (harmless threat)

A

Hypersensitivity

36
Q

This Hypersensitivity begins in seconds after allergies have been exposed to the body

A

Acute or type one

37
Q

This is a Hypersensitivity where there is a systemic shock when the allergin enters the blood

A

Anaphylactic shock

38
Q

Antibodies bind to antigens on specfic body cells that simulate phagocytosis in this subacute Hypersensitivity

A

Cytotoxic or type II