Part 2 Flashcards
Antibodies are proteins secreted by ______ cells and are capable of binding to specific antigens
Plasma
Antibodies consist of four protein chains, two identical _____ and two ____ chains.
Heavy
Light
The variable region functions as the ______ _______ site where the constant region of the stem determines the _____ class
Antigen binding
class
Antibody that attaches to the surface of cells
IgD
Antibody that is active in some allergies and parasitic infections
IgE
First antibody released
IgM
Antibody found in mucus and other secretions
IgA
Antibody that crosses the placental barrier
IgG
Antibody that works as a pentamer
IgM
Antibody that helps prevent entry of pathogens in the body
IgA
75-85% of antibodies in plasma
IgG
Readily fixes and activates complement
IgM
Potent agglutinating agent
IgM
Functions as B cell receptor
IgD
Released in secondary and late primary response
IgG
Causes mast cells and basophils to release histamine
IgE
This is a defense mechanism used by antibodies that block specifics sites on viruses
Neutralization
This is a defense mechanism used by antibodies that causes them to bind the same determinant on more than one cell-bound antigen
Agglutination
This is a defense mechanism used by antibodies that is when soluble molecules are cross-linked
Precipitation
This is the main antibody defense against cellular antigens
Complete fixation and Activation
In cell mediated immune response, ___ cells provide defense against intracellular antigens
T cells
The two major types of T lymphocytes are ___ which turn into helper T cells and ___ that turn into cytoxic
CD4
CD8
MHC Class I proteins are displayed by all cells except
RBCs
MHC class II proteins are displayed by
APC