Part 1 Flashcards
Genes
Sequences of DNA transcribed into RNA molecules
Genome
Complete DNA set of an organism
Proofreading
Mechanical that corrects errors in replication as DNA polymerase makes them
Mismatch repair
Mechanism that scans DNA immediately after it has been replicated and corrects any base-pairing mismatches
Excision repair
Mechanism that removes abnormal bases that have formed because of chemical damage and replaces them with functional bases
Evolution
Change in genetic composition of POPULATIONS over time
Descent with modification
Darwin terms as species with common ancestors gradually diverged from each other over time
Gene pool
Sum of all copies of all alleles loci found in a population
Locus
Particular site on a chromosome
Allele frequency vs. Genotype frequency
Proportion of each allele in the gene pool VS. Proportion of each genotype among the individuals in the population
Artificial selection
Purposeful selection of specific phenotypes by humans
Positive vs. Purifying selection
Selection for beneficial changes VS. Selection against deleterious changes
Chromatin
Complex of DNA and proteins
Nucleosomes
Bead-like units of DNA-histone or histone-histone interactions
Kinetochores
Specialized 3 layered structures developed on the centromere region of each chromatid during late prophase