parkinsons Flashcards
dopamine is an… hormone
inhibitory
AcH is an… hormone
excitatory
motor S&S
TRAP
Tremor
Rigidity
Akinesia
Postural instability
non motor S&S
depression
anxiety
urinary retention
constipation
sleep problems
complications over time
dyskinesia
dementia
psychiatric
dysphagia
debilitation
orthostatic hypotension
dopamine precursors
levodopa and carbidopa
highest dose without OD
dopamine agonists
amantadine
apomorphine
*subq
* antiemetic
anticholinergics
benztropine
trihexyphenidyl
dopamine receptor agonists
pramipexole
ropinerole
rotigotine
antihistamines
diphenhydramine
MOA-I
Selegiline
Rasagiline
Safinamien
- delays need for levodopa therapy and strengthens it when given in combo
what can MOA-I not be given with
tyramine
prozac
demerol
COMT stands for…
catechol O-methyltransferase
COMT inhibitors
entacapone
tolcapone
- very expensive
- give with levodopa and carbidopa
- watch for liver tox.
surgical management techniques
deep brain stimulation
ablation
types of ablation
thalamotomy
- relieves tremors
pallidotomy
- relieves stiffness
