Parkinson’s Drugs Flashcards by Aisha Musa | Brainscape

Q

Day time sleepiness

A

Modafinil

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Q

Nocturnal Akinesia

A

1st line: Levodopa or D2 receptor agonist

2nd line: Rotigotine

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Q

Postural Hypotension

A

1st line: Midodrine

2nd line: Fludrocortisone

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Q

Psychotic symptoms in Parkinson’s?

A

1st line: Quetiapine

2nd line: Clozapine

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Q

Rapid eye movement sleep behaviour

A

Clonazepam or Melatonin

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Q

Drooling saliva

A

1st line: Glycolyrronium bromide

2nd line: Botulinum toxin A (Botox)

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Q

Dementia

A

For mild-moderate Parkinson’s

1st line: Cholinesterase inhibitors

NOT RIVASTIGMINE!

2nd line: Memantine

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Q

Antiemetics in Parkinson’s?

A

Domperidone

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Q

Which drug may exacerbate oedema?

A

Amantadine

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Q

Which drug may cause hair loss?

A

Bromocriptine

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Q

Which drug should you AVOID OTC sympathimimetics?

A

MAO-A inhibitors (selegeline/rasigiline)

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Q

Used in advanced Parkinson’s via injections / infusions?

A

Apomorphine

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Q

What to look out for with bromocriptine/cabergoline?

A

Fibrotic reactions - monitor for signs of:

dysponea
persistent cough
chest pain
cardiac failure
abdo pain

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