Parkinson's Flashcards
What causes Parkinson’s Disease’s symptoms?
Loss of domaminergic neurons in the substantia nigra
The formation of which protein in Parkinson’s is shared with a dementia type?
Lewy Bodies
What is the role of dopamine?
Where is the substantia nigra located?
Pars compacta vs pars reticula - how do the function of these differ?
PC = Contains dopamine neurons
PR = Movement regulator
In which section of the brain in the Pars Compacta and Pars Reticula located?
Midbrain
What is Dyskinesia and how does it typically present in Parkinson’s
Involuntary and abnormal movements - tremors/shaking
What is Bradykinesia?
Slowed movements
What is Hypophonia?
Comes under Bradykinesia - softer + quieter voiced due to slowed muscles of speech
What is Facial Masking?
Comes under Bradykinesia - reduced/delayed facial expressions
What is Bradylalia?
Slow speech rate
What is Festination?
Increased movement speed but reduced range of motion
What is dysarthria?
Weakened muscles causing slurred speech
What is Hypokinetic Dysarthria
Weakened muscles causing difficulty with initiating speech or causing stuttering/slurring
