Parkinson’s

Question 1

Pakinson’s disease causes degeneration of […] neurons in […] in midbrain

Answer 1

Dopaminergic neurons
In Substantia nigra

Question 2

Clinical findings of Parkinson’s disease

Answer 2

Tremors (resting, asymmetric at onset)
Rigidity (cogwheel)
Akinesia/Bradykinesia
Postural instability
Shuffling gait
Small handwriting (micrographia)
————————————————
2/4 diagnosis

Question 3

Medication induced parkinsonism
Include drugs like:
[…]
[…]
[…]

Answer 3

🔸Metoclopramide .. N&V
🔸Haloperidol .. antipsychotic
🔸Methyldopa .. antihypertensive

Question 4

The tremor in parkinson’s disease is […]
VS in medication induced parkinsonism […]

Answer 4

PD: Asymmetric at onset
💊: Symmetric at onset

Question 5

Early dementia within the first year of the appearance of Parkinsonism is a hall mark of […]

Answer 5

Dementia with Lewy body !

Question 6

First line Medical treatment of PD

Answer 6

Levodopa/carbidopa

Question 7

What medication could improve parkinson’s tremor & regidity ?

Answer 7

Antimuscarinic
(Benzotropine & Trihexyphenidyl)

Question 8

[…] in PD treatment is mainly used to reduce Levodopa-induced dyskinesias

Answer 8

Amantadine