Parkinson's Flashcards

1
Q

Autonomic syfunction

A

Postural hypotension

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2
Q

Difference with drug induced parkinsonism

A

motor symptoms are generally rapid onset and bilateral
rigidity and rest tremor are uncommon

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3
Q

Imaging

A

SPECT

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4
Q

If no motor symptoms, what drug

A

MAO-B or dopamine agonists (fewer motor complications)

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5
Q

Complications of dopamine agonists

A

Visual hallucinations, impulse disorders

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6
Q

If levodopa insufficient

A

Add MAO-B, dopamine agonist or COMT

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7
Q

Complication management

A

Sleepiness - modafinil
orthostatic hypotension - midodrine
Drooling - glycopyrronium bromide

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8
Q

Common SEs of levodopa

A

palpitations
postural hypotension
psychosis

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9
Q

If hospitalised and acutely stopped levodopa

A

dopamine agonist patch

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10
Q

Examples of dopamine agonists

A

bromocriptine, ropinirole, cabergoline, apomorphine

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11
Q

If drug-induced parkinsonism

A

procyclidine

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