Dementias

Question 1

Most common

Answer 1

Alzheimer’s
Vascular
Lewy Body

Question 2

What MMSE score suggests dementia

Answer 2

24 OR UNDER

Question 3

Management

Answer 3

Screen for reversible cause
FBC, U&E, LFTs, calcium, glucose, ESR/CRP, TFTs, vitamin B12 and folate levels
Neuroimaging –> exclude Subdural haematoma, normal pressure hydrocephalus

Question 4

Lewy bodies

Answer 4

Alpha synuclein inclusion bodies

Question 5

Where are Lewy bodies commonly

Answer 5

substantia nigra, paralimbic and neocortical areas.

Question 6

Since on substantia nigra, what other disease is associated with LB

Answer 6

Parkinson’s disease

Question 7

What other dementia is associated with Lewy body

Answer 7

Alzheimer’s

Question 8

How to differentiate LB from Parkinson’s

Answer 8

Cognitive impairment BEFORE parkinsonism

Cognition fluctuates

Visual hallucinations

Question 9

What drugs to avoid in LB

Answer 9

Antipsychotics

Question 10

How to differentiate between depression and dementia

Answer 10

Depression presents with short history, rapid onset, biological symptoms and global memory loss

Question 11

How to differentiate delirium from dementia

Answer 11

Delirium presents with IMPAIRED CONSCIOUSNESS