PARENTERAL Flashcards
method of providing macronutrients & micronutrients to those who are unable to assimilate nutrients via the GIT
Parenteral Nutrition
What are the INDICATIONS of PN
-Non-Functioning GIT
-Bowel Rest
-Severe Malnutrition
-Patient unable to eat orally ≥5 days
-Anticipated return to enteral nutrition is <7-10 days for Adults, 3-5 days for Infants/Children
CONTRAINDICATIONS of PN
-Functioning GIT
-Duration of anticipated treatment is <5 days provided patient is not severely malnourished
-Inability to obtain venous access
-Any prognosis which not warrant an aggressive form of nutrition support
3 ways of estimating TER in Parenteral Nutrition
- Calorie/Weight Method
- Harris-Benedict Equation for Basal Energy Expenditure
- Indirect Calorimetry & Oxygen Consumption Measurements
Provide the GOALS and corresponding kcal/kg BW/day of Calorie/Weight Method
-Resting Metabolic Expenditure = 25
-Maintenance = 30
-Anabolism = 35
What is the Harris-Benedict Equations for Basal Energy Expenditure in MALES?
TER = 66.47 + 13.75W (kg) + 5H (cm) - 6.75A (yrs)
What is the Harris-Benedict Equations for Basal Energy Expenditure in FEMALES?
TER = 655.1 + 9.56W (kg) + 1.85H (cm) - 4.67A (yrs)
Provide the GOALS and corresponding FACTOR of Harris-Benedict Equations for BEE
-Maintenance = BEE x 1.2
-Anabolism = BEE x 1.5
In Estimation of Fluid Requirements:
What are the approximate body fluid and fluid volumes by GIT secretion?
-Saliva = 1500 mL
-Gastric = 2500 mL
-Bile = 500 mL
-Pancreatic Juice = 700 mL
-Small Intestines = 3000 mL
Estimation of Fluid Requirements by Sex
-Ave. Males = 125 mL/hr (3L/day)
-Ave. Females = 100 mL/hr (2.4L/day)
Minimum acceptable Urine Output (UO)
900 mL/day
Estimation of Fluid Requirements by Method 1 (Adults & Older Adults)
Provide each category and corresponding volume
-Young, vigorous, previously healthy adult = 40 mL/kg
-Other adults = 35 mL/kg
-Older adults (elderly) = 25 mL/kg
Estimation of Fluid Requirements by Method 2 (Based on Body Weight)
Provide each weight and corresponding volume
-1st 10 kg = 100 mL/kg/day
-2nd 10 kg = 50 mL/kg/day
-each addition kg for:
»> ≤50 y/o = 20 mL/kg/day
»> >50 y/o = 15 mL/kg/day
Estimation of Fluid Requirements by Method 3 (Based on Goal)
Provide each goal and corresponding volume
-Maintenance = 60 mL/kg/day
-Replacement = 70 mL/kg/day
Guiding Principles in CARB REQUIREMENTS
- for a 70 kg man:
1 mg/kg/min HCHO or 100 g/day
Guiding Principles in CARB REQUIREMENTS
- Maximum CHO
5 mg/kg/min
Guiding Principles in CARB REQUIREMENTS
- Dextrose =
3.4 kcal/g
Guiding Principles in CARB REQUIREMENTS
- Final Dextrose conc should not exceed _____% (Peripheral) or ____%(Central)
-5% (Peripheral)
-35% (Central)
Guiding Principles in CARB REQUIREMENTS
- Glucose Infusion Rate should not exceed _____
5-7 mg/kg/min
PROTEIN REQUIREMENTS per condition
-Maintenance = 0.8-10 g/kg/day
-Minor Stress/Surgery = 1.25 g/kg/day
-Moderate Stress/Surgery = 1.50 g/kg/day
-Severe Stress/Trauma/Burns/Sepsis = 2.0-2.5 g/kg/day
Guiding Principles in PROTEIN REQUIREMENTS:
- ___% of CHON/Amino Acids = Nitrogen (Protein Intake: ___ X amount of Nitrogen in g)
-16%
-6.25
Guiding Principles in PROTEIN REQUIREMENTS:
- CHON should provide ____ of TER
15%
Guiding Principles in PROTEIN REQUIREMENTS:
- In adults, PN should be able to provide _______ CHON/kg BW/day
1-2 g
Guiding Principles in PROTEIN REQUIREMENTS:
True or False
- Excess CHON intake leads to CHON accumulation in the body
FALSE!
Excess CHON intake DOES NOT lead to CHON accumulation in the body
Guiding Principles in PROTEIN REQUIREMENTS:
- For normal individuals: _______ is needed for the optimal utilization of 1 g of N atom
300 non-CHON kcal
Guiding Principles in PROTEIN REQUIREMENTS:
- In critical illness: _______ is needed for the optimal utilization of 1 g of N atom
100-150 non-CHON kcal
Guiding Principles in PROTEIN REQUIREMENTS:
- Amino Acid PN solution should provide
4 kcal/g
Guiding Principles in PROTEIN REQUIREMENTS:
- Final amino acid concentration in PN solution should not exceed:
-4.25% for 3-in-1 solutions
-7.5% for non 3-in-1 solutions
Guiding Principles in PROTEIN REQUIREMENTS:
- Adjustments for ______ should be applied
organ failure
Guiding Principles in PROTEIN REQUIREMENTS:
Provide each condition and corresponding value for organ failure adjustments
(No. 9)
-On chronic hemodialysis = 1-1.29 g/kg/day
-On chronic ambulatory peritoneal = 1.2-1.5 g/kg/day
-Creatinine Clearance <30 mL/min = 0.5-1.0 g/kg/day
Guiding Principles in PROTEIN REQUIREMENTS:
- Calorie:Nitrogen ratio Goals
-promote optimal utilization of N
-decrease gluconeogenesis with possible associated pre-renal azotemia
What is azotemia?
accumulation of nitrogenous products
Guiding Principles in PROTEIN REQUIREMENTS:
Provide each clinical status and corresponding calorie:nitrogen ratio
(No. 10)
-Mild-moderate stress = 133:1 (as NPC)
-Severe Stress (ex. Sepsis/Trauma) = 100:1
-Renal Patients = 250:450
Guiding Principles in FAT REQUIREMENTS:
- For prevention of Essential Fatty Acid Deficiency (EFAD):
-____% of TER should come from Linoleic Acid (_____ mg/kg/day): ___ or ___ oil
-EFAD occurs if fat is not added to the ______ after ___ days
-____ mL fat emulsion every ____ days is sufficient
-Do not exceed _____ g/kg/day
-infuse over ____ hrs
-2-4% of TER should come from Linoleic Acid (25-100 mg/kg/day): Soy or Safflower oil
-EFAD occurs if fat is not added to the PN solution after 5 days
-500 mL fat emulsion every 5 days is sufficient
-Do not exceed >2.5 g/kg/day
-infuse over 12 hrs
Guiding Principles in FAT REQUIREMENTS:
- Fat should not exceed ____ of TER
> 60%
Guiding Principles in FAT REQUIREMENTS:
- In sepsis: fat should not exceed ____ of TER
> 20%
Guiding Principles in FAT REQUIREMENTS:
- 10% fat emulsion =
1.1 kcal/mL
Guiding Principles in FAT REQUIREMENTS:
- 20% fat emulsion =
2.0 kcal/mL
Guiding Principles in MICRONUTRIENT REQUIREMENTS:
- Vitamins are mixed with ____ just prior to _____
vitamins are mixed with PN SOLUTION just prior to INFUSION
Guiding Principles in MICRONUTRIENT REQUIREMENTS:
- Vitamin K is added: _____mg/week (not done if patient is on ______ therapy)
-2-4 mg/week
-coumarin/warfarin therapy
Guiding Principles in MICRONUTRIENT REQUIREMENTS:
- Extracellular electrolytes: Non-stressed, average individual
(Provide electrolyte and corresponding value)
-Sodium = 50 mEq/L
-Chloride = 50 mEq/L
-Acetate = 50 mEq/L
Guiding Principles in MICRONUTRIENT REQUIREMENTS:
- Intracellular electrolytes: for every ____ NPC
750-1000
Guiding Principles in MICRONUTRIENT REQUIREMENTS:
Provide each intracellular electrolytes and corresponding value.
(No. 3)
-Potassium = 40 mEq/L
-Phosphate = 5 mEq/L
-Magnesium = 8 mEq/L
-Calcium = 10 mEq/L
-Zinc = 5 mEq/L
Amino acid content of each commercially available solutions:
- Nutriflex Peripheral
- Nutriflex Basal
- Nutriflex Plus
- Nutriflex Special
- Nutriflex Peripheral (40/80)
- Nutriflex Basal (32/125)
- Nutriflex Plus (48/150)
- Nutriflex Special (70/240)
This is available in a 3-chamber bag system.
Kabiven Peripheral
Each bag of Kabiven Peripheral contains:
-glucose (largest chamber)
-amino acids & electrolytes
-fat emulsion (white solution)
True or False
Electrolytes in Kabiven Peripheral can be mixed with glucose
True
True or False
Electrolytes in Kabiven Peripheral can be mixed with fat
False