Parasitology I and II - Study Questions

Question 1

List the protozoa spread from human-to-human and animal-to-human

Question 2

List the vector-borne protozoal diseases with its vector.

Question 3

List the protozoa acquired from inadequate preparation of meat

Question 4

List the diagnostic method to detect infection for the following protozoa

a. Plasmodium falciparum
b. Leishmania tropica
c. Trypanosoma cruzii
d. Giardia lamblia
e. Cryptosporidium
f. Entamoeba histolytica
g. Toxoplasmosis

Question 5

List protozoa indigenous to the U.S. Mainland and those imported.

Question 6

For which of the protozoal diseases are chemoprophylactic medications prescribed to either prevent infection or interrupt maturation and replication

Question 7

Which malaria species can persist in the liver and relapse in the blood after treatment.

Answer 7

SX- Fever is associated with schizont rupture

Question 8

Name the organs most severely affected in fulminant falciparum malaria

Question 9

Which malaria species accounts for the majority of chloroquine resistance throughout the world

Answer 9

P. falciparum

• RBC Receptor: Glycophorin A*
• can in fect all types of RBCs*
• NO hepatic dormancy*
• Rarely seen in P. vivax (RBC receptor Duffy antigen) and NOT SEEN IN P. ovale and P. malariae*

Question 10

The sexual phase of the malaria life cycle in which gametocytes mature to the sporozoite is known as ___________________________.

Answer 10

SPOROGONY

occurs in the MOSQUITO

gametocyte (male and female; fuse in the gut of mosquito) –> zygote —> oocyst –> sporozoite (in the saliva

(sporozoite is located in the salivary secretion of the mosquito –>infectious form)

Question 11

It is not important to differentiate malaria species on the basis of blood smear morphology. True or False?

Answer 11

FALSE!

•P. vivax and P. ovale Schuffner’s dots - caveole -vesicle complexes

•P. falciparum - electron dense knobs

–Facilitate binding to endothelium and uninfected RBCs

Question 12

Name the human cell in which babesia species are found.

Question 13

Which morphologic stage of leishmania is seen within macrophages in skin biopsy in the cutaneous form or in the liver or spleen in the visceral form

Question 14

Which morphologic stage of trypanosome circulates in the blood of people infected with Trypanosoma cruzi or Trypanosoma brucei gambiense?

Question 15

Which protozoan causes megaesophagus or megacolon?

Question 16

The insect vector of Trypanosoma cruzi is the __________________________.

Question 17

The sexual phase of the life cycle of Toxoplasma gondii takes place in the ___________________________.

Question 18

How do humans acquire infection with Toxoplasma gondii?

Question 19

What is the most common manifestation of toxoplasmosis in persons with AIDS?

Question 20

How is the specific diagnosis of Pneumocystis jiroveci pneumonia established?

Question 21

Name the infective form of Entamoeba histolytica

Question 22

The organ most commonly involved in extra-intestinal amebiasis is the _______________________________.

Question 23

What cells are often found in vacuoles within amebic trophozoites seen in clinical specimens from patients with invasive dysentery caused by Entamoeba histolytica?

Question 24

The major site of infection with Giardia lamblia is ___________________________.

Question 25

Giardia lamblia causes diarrhea by _________________________________________.

Question 26

The clinical manifestation caused by cryptosporidium if it is acquired by healthy people is ____________________________________

Question 27

Cryptosporidia have caused large outbreaks of waterborne diarrheal disease in the U.S. True or False?

Question 28

Cryptosporidium causes chronic debilitating diarrhea in people with ___________________________________.