Parasitism/Sepsis-Related Diseases Flashcards
What are the 3 most common soil-transmitted helminths?
HAT
Hookworms
Ascariasis
Trichuriasis
What is the most common presentation of scariasis?
Passing out of worm per rectum = spaghetti-like worm
What is the worst case scenario of Ascariasis?
Acute intestinal obstruction = heavy bolus of worm in the intestine of the child
What is the pathognominic feature of Ascariasis?
Larval migratory phase (Loeffler syndrome)
What are the treatment for ascariasis?
Albendazole
Mebendazole
Ivermectin
What are the DOC of ascariasis?
Albendazole & Mebendazole
What is the weight requirement for giving of Ivermectin for Ascariasis?
Children <15kg
What are the most common hookworms that infect man?
Necator americanus (PH)
Ancylostoma duodenale
What is peculiar to hookworm infection?
Microcytic hypochroimc anemia = manifests as pallor
What is the symptom of hookworm in the lungs?
Verminus pneumonia?
What are the tx for Hookworm?
Albendazole
Mebendazole
Pyrantel
Pamoate
What age grps are recommended to do derworming?
Young children (12-23 months)
Preschool (24-59 mons)
School age children
Non-pregnant adolescents (10-19yo)
Non-pregnant women of repro age (15-49yo)
Living in areas where baseline prevalnce of any soil=transmitted helminth infection is >20%
What are the specific drug recommendations in 1-24 months of age for dewrming?
Albdendazole = 200mg (single dose every 6mons)
Mebendazole = 500mg (single dose every 6mons)
What are the specific drug recommendations for deworming of >24 months age children?
Albedazole = 400mg (single dose every 6mons)
Mebendazole = 500mg (single dose every 6mons)
What are the specific drug recom for Adolescent females for deworming?
Albendaozole = 400mg once a yr
Mebendazole = 500mg
What is the common clin feature of Filariasis in infected children?
Filarial lymphadenopathy
What is a selective treatment for Filariasis?
Diethylcarbamazine citrate (positive for microfilariae)
What is the drug used for mass treatment of Filariasis?
Diethylcarbamazine citrate + Albendazole
What is the acute infection of Schistosomiasis?
Swimmer’s itch
Katayama fever
What is the dx test of choice in the PH for Schistosomiasis?
Circumoval precipitin test
What are chronic or late clin manifestations of Schistosomiasis?
Granulomas
Fibroblat cells also a site of infection
What is the DOC for Schistosomiasis?
Praziquantel
What is the management for diarrhea?
Oral rehdyration salts
What are the top 4 symptoms of childhood leptospirosis?
Fever
Abdominal pain
Myalgia and or joint pain
Headache
What are the top 3 signs of childhood leptospirosis?
Calf tenderness
Jaundice
Hepatomegaly
What is the 1st line and 2nd line of tx for Uncomplicated leptospirosis?
1st line = doxycycline
2nd line = amoxicillin or azithromycin
What are the 1st line and alternative tx to Moderate to severe leptospirosis?
1st line = Penicillin
Alternative = Cefotaxime, Ceftriaxone