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Pharmacology > Parasiticides > Flashcards

Parasiticides Flashcards

1
Q

What is the MoA of Bendamidazoles?

A

Inhibition of microtubules

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2
Q

What is the MoA of Closantel, Niclosamide?

A

Uncoupling of oxidative phosphorylation

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3
Q

What is the MoA of Clorsulon, Melarsomine?

A

Inhibition of glycolysis

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4
Q

What is the MoA of Levamisole, Neonicotinoids (Imidicloprid, Capstar)?

A

Nicotinic agonist

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5
Q

What is the MoA of Spinosads (Comfortis), Tetrahydropyramides?

A

Nicotinic agonist

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6
Q

What is the MoA of Tetrahydropyramides (Pyrantel, morantel, oxantel), monepantal?

A

Cholinergic agonist

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7
Q

What is the MoA of dequantel?

A

Nicotinic antagonist

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8
Q

What is the MoA of Carbamates, organophosohates?

A

AChE inhibitor

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9
Q

What is the MoA of Emodepside?

A

Latrophilin agonist

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10
Q

What is the MoA of Piperazine?

A

GABA agonist

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11
Q

What is the mechanism of action of Fipronil, Isoxazolines (-laner)?

A

GABA antagonist

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12
Q

What is the MoA of Praziquantel?

A

interferes with ionic balance

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13
Q

What is the MoA of Pyrethrins, synthetic pyrethroids?

A

Prolonged Na+ channel opening

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14
Q

What is the MoA of indoxacarb?

A

Blocks vgNa+

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15
Q

What is the MoA of Benzoylphenylureas (-uron)?

A

Interference with Chitin

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16
Q

What is the MoA of Methoprene, Fenoxycarb, Pyriproxyfen

A

Juvenile hormone analogues

17
Q

What is the MoA of Formamidines (amitraz)?

A

Octopamine receptor agonist

α-adrenergic agonist

Prostaglandin inhibitor

18
Q

What is the MoA of Macrocyclic lactones (-mectins, mycins)?

A

Agonists at glutamate gated Cl- channels

19
Q

What drug classes have action against Giardia?

A

BZs:
Metronidazole

Fenbendazole

Febental

20
Q

Which drugs have action against fleas, but not ticks?

A

Imidacloprid (Advantage)

Nitenpyram (Capstar)

Indoxacarb

Juvenile hormone analogues (Methoprene, Fenoxycarb, Pyriproxyfen)

21
Q

Which drugs have actions against ticks, but not fleas?

A

MLs (-mectins, -mycins)

Amitraz

Pharmacology (12 decks)

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