Parasitic Infections Flashcards
what is a PARASITE
An organism that lives in (or on) (infects) the host and is dependent on it for nutrition, often causing damage or disease
What are protozoa
are single-celled eukaryotic organisms whose pathogenesis is varied and many are carried by insect vectors
- They do not produce eosinophilia in the host
What are metazoa
- Helminths/worms are complex multicellular organisms known as metazoa which can be free living or transmitted by vectors and their lifecycle involves an intermediate host – humans are the definitive host
- Adult worms lay eggs or produce microfilariae but cannot themselves multiply in man, so they’re a cause of morbidity rather than mortality
- Forms which invade the blood often cause eosinophilia
Do protozoa evoke eosinophilia
No
Do metazoa evoke eosinophilia
Yes
What are ectoparasites
Parasites that live externally
What are endoparasites
Parasites that live internally
4 types of protozoa?
Amoeba, coccidiae, ciliae, flagellates
3 examples of metazoa?
roundworms, flatworms, flukes
Difference between protozoa and metazoan?
Protozoa: single celled, no eosinophilia, can cause mortality
Metazoa: multicellular, eosinophilia, cause morbidity rather than mortality
2 examples of ectoparasites?
Scabies, live
Example of an amoeba?
Entamoeba histolyca
What does Entamoeba histolyca cause?
bloody diarrhea (dysentery) when it infects the colon and can also lead to abscess formation in the liver – these amoebae can ingest red cells
Example of an coccidiae? (3)
- Plasmodium species e.g. P. falciparum, ovale, vivax, knowlesi and malariae cause malaria – the lifecycle involves the invertebrate (Anopheles mosquito) and the vertebrate (man)
- Toxoplasma gondaa
- Cryptosporidium
What type of parasite is Entamoeba histolyca
Amoeba
What type of parasites are plasmodium
Coccidiae
Pathophysiology of malaria? (5)
febrile illness, paroxysm, cerebral malaria, respiratory distress and severe anaemia
What type of parasite is Toxoplasma gondaa
coccidia
What type of parasite is Cryptosporidium
coccidia which can infect the small bowel and produces severe diarrhea – infection is commonly waterborne/faeco-oral
What does cryptosporidium cause
coccidia which can infect the small bowel and produces severe diarrhea – infection is commonly waterborne/faeco-oral
How do you diagnose malaria? (2)
Blood films are used to diagnose, rapid test is also available via antigen detection test
Example of Flagellate? (4)
- Giardia
- Trichomonas
Lieshmania
Trypanosoma (Tsetse flies)