Paraneoplastic syndromes

Question 1

Aside from saline rehydration, treatment of severe hypercalcemia may also include the
following measures

Answer 1

GI
Pamidronate
Calcitonin

Question 2

Ectopic production of intact Human Chorionic Gonadotropin (hCG) is often encountered in association with

Answer 2

Testicular embryonal tumors

Question 3

The most common cause of Superior Vena Cava syndrome (SVCS), responsible for 85% of cases

Answer 3

Lung cancer

Question 4

When SVCS is encountered in a young man with a mediastinal mass, the main differential diagnosis is lymphoma vs

Answer 4

Primary mediastinal germ cell tumor

Question 5

Diagnostic modality of choice for SVC syndrome

Answer 5

Ct scan

Question 6

While awaiting definitive management , patients with SVCS due to lymphoma may benefit from immediate treatment with

Answer 6

GC

Question 7

primary treatment for SVCS caused by non-small cell lung cancer and other metastatic solid tumors

Answer 7

RT

Question 8

Distinctive pain characteristic of back pain from cord compression

Answer 8

Unlike disc disease, pain worsens when patient is supine

Question 9

earliest radiologic finding of vertebral tumor

Answer 9

Erosion of the pedicles (“winking owl sign”)

Question 10

rain leukostasis , which may present with stupor, headache, visual disturbances, or coma, is a potentially fatal complication of

Answer 10

Acute myeloid leukemia

Question 11

most common paraneoplastic syndrome

Answer 11

hypercalcemia

Question 12

Acute renal failure in tumor lysis syndrome is usually caused by:

Answer 12

Acute uric acid nephropathy

Question 13

treatment of choice for hemorrhagic cystitis caused by alkylating agents such as cyclophosphamide and ifosfamide:

Answer 13

2-mercaptoethanesulfonate (mesna)

Question 14

Paraneoplastic Oncogenic osteomalacia

Answer 14

Phosphatonin