General Oncology Flashcards
1
Q
property of tumor cells to form mosaics with endothelial cells to form the lining of tumor vessels, creating cancer-cell derived vascular channels
A
Vascular mimicry
2
Q
ability of tumor to promote the formation of new capillaries from pre-existing host vessels
A
Angiogenic switch
3
Q
most potent trophic angiogenic molecule secreted by tumor cells that induce
proliferation and migration of host endothelial cells into the tumor
A
VEGF
4
Q
refers to a family of enzymes that catalyze the formation of estrogen in various
tissues, including the ovary, adipose tissue and some tumor cells
A
Aromatase (aromatase inhibitors include exemestane, anastrozole, letrozole)
5
Q
Which of the following chemotherapeutic agents is MOST emetogenic
A
Cisplatin
