Paraneoplastic Syndrome Flashcards
What are dermatological paraneoplastic syndromes
Achanthosis nigricans
Dermatomyositiss
Seborrheic keratosis
What are dermatological paraneoplstic syndrome occur in lung cancer
Acanthosis nigricans
Dermatomyositis
Explain about achantosis nigricans
Occurs in
stomach cancer
Lung cancer
Uterine malignancy
Hyperpigmentation occurs here and thickening of skin occurs
Dermatomyositis
Seen in
Lung cancer
Breast cancer
Seborrheic keratosis
Stomach
Breast
Colon
What is paraneoplastic syndrome?
Here it cannot be explained
Metastasis
Hormones indigenous
Directi spread
What is the significance paraneoplastic syndrome
Metastasis mimic
Indicate the worsen condition
May be initial manifestation
Types of paraneoplastic syndrome
Endocrinopathies Dermatological Neuromuscular Osseus or soft tissues changes Vascular haemotogical
Endocrinopathis features
Here first we are gonna learn headings Hypercalcemia Cushing syndrome Polychethemis Siadh Hypoglycaemia
How hypercalcemia occur
Hypercalcemia occurs in
Lung cancer
Kidney cancer
Breast cancer
Most common paraneoplastic syndrome
Occurs due to presence of prostaglandins and the path like peptides
Explain Cushing syndrome as the paraneoplastic syndrome
It occurs in
Small cell carcinoma of lung
Carcinoid tumour
Most common endocrine paraneoplastic syndrome
Siadh
Increased ADH
In severe cases the hyponatrimea
Occurs in
Small cell lung cancer
Cns tumour
Hypoglycaemia is seen in
Fibrosarcoma
Ovarian cancer
Polycythemia as the neoplastic syndrome
Occurs in
Kidney cancer
Hepato cellular carcinoma
Cerebellar hemangioblastoma
It occurs due to increase in erythropoietin
What are the paraneoplastic syndrome occurs in lung. Cancer
Cushing syndrome
Hypercalcemia
Siadh
Examples of vascular paraneoplastic syndromes
Venous thrombophlebitis ( migratory thrombophlebitis)
Marantic endocarditis/ non bacterial thrombotic endocarditis
Anemia seen in thymoma
Explain the venous thrombophlebitis
Caused due to the mucin
Migratory thromnhophLebitis,
trousseau sign
Seen In
Pancreatic cancer
AML-M3
Bronchogenic cancer/ adrenocarcinoma of lung
Explain marantic endocarditis/ non bacterial thrombotic endocarditis
Seen in pancreatic cancer
AML-m3
Due to mucin
Neuromuscular paraneoplastic syndromes
Myasthenia gravies
Lamberts eaten syndrome
Myasthenia bra is in paraneoplastic syndromes
Thymoma
Lung cancer
Lambert eaten syndrome
Lung cancer
Limbic encephalitis
Lung cancer
Small cell
Sub acute cerebellar deneratiom
Endometrial cancer
Ovarian cancer
Breast cancer
Opsoclonu random eye movement
Small cell lung cancer
Seen in neuroblastoma
How Osceous and soft tissue are effected
Hypertrophic Osteo arthropathy
Causes the clubbing of fingers
Lung cancer
