Paracetamol Overdose Flashcards
1
Q
what is normal levels of paracetamol to take?
A
2 x 500 mg tablets, 4 x in 24 hrs
2
Q
how much is dangerous?
A
> 12 g
3
Q
risk factors for paracetamol overdose?
A
o Chronic alcohol abusers o Patients on enzyme-inducing drugs (e.g. anticonvulsants) o Malnourished o Anorexia nervosa o HIV o mental health problems
4
Q
symptoms and signs at 24 hours?
A
o ASYMPTOMATIC
o Mild nausea/vomiting
o Lethargy
o Malaise
5
Q
symptoms and signs at 24-72 hours?
A
o RUQ pain
o Vomiting
o liver enlargement
o tenderness
6
Q
symptoms and signs after 72 hours?
A
o Increased confusion (encephalopathy) o Jaundice o Coagulopathy o Hypoglycaemia o Renal angle tenderness
7
Q
what will the liver enzymes show on blood?
A
- ALT and AST will be in the 10,000s
8
Q
important measure?
A
paracetamol levels
they will peak at 4 hours after injestion
