Paracetamol Flashcards
1
Q
Paracetamol
A
- Acute and chronic pain treatment
2. Antipyretic
2
Q
Paracetamol - MOA
A
Paracetamol is a weak inhibitor of cyclo-oxygenase (COX2)
3
Q
Paracetamol - side effects
A
Overdose = liver failure
4
Q
Paracetamol - cautions
A
chronic alcohol abuse
malnutrition
low body weight
severe hepatic impairment
5
Q
Paracetamol - interactions
A
CYP inducers - phenytoin and carbamazepine
Why? increases risk of liver toxicity after OD