Paracetamol Flashcards

1
Q

Paracetamol

A
  1. Acute and chronic pain treatment

2. Antipyretic

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2
Q

Paracetamol - MOA

A

Paracetamol is a weak inhibitor of cyclo-oxygenase (COX2)

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3
Q

Paracetamol - side effects

A

Overdose = liver failure

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4
Q

Paracetamol - cautions

A

chronic alcohol abuse

malnutrition

low body weight

severe hepatic impairment

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5
Q

Paracetamol - interactions

A

CYP inducers - phenytoin and carbamazepine

Why? increases risk of liver toxicity after OD

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