Opioids Flashcards
1
Q
Opioid - examples
A
Strong
1) oxycodone
2) morphine
Weak/mod
1) tramadol
2) codeine
3) dihydrocodeine
2
Q
Opioids - MOA
A
1) Opioids activate opioid µ receptors in the CNS
2) This reduces neuronal excitability and pain transmission
3) This reduces sympathetic nervous system activation
3
Q
Opioids - adverse effects
A
- respiratory depression
- neurological depression
- nausea/vomiting
- constipation
- itching
- withdrawal reaction - anxiety, pain, SOB
- dependence
4
Q
Opioids - caution
A
- hepatic failure
- renal impairment
- elderly
- resp failure
- biliary colic
