Paper 1 A1 Flashcards
3 polysaccharides
Starch Glycogen Cellulose
Bond between glucose molecules
Glycosidic bond (1-6/1-4)
Glucose + Glucose
Maltose +H2O
Glucose + Fructose
sucrose + H2O
Cell mediated response
Present antigens on cell surface membrane of a phagocyte
Complimentary T -helper cell binds to antigen
T-cell undergoes clonal expansion
T-helper cells, Cytotoxic T-killer cells and T- memory cells
Humoral response
B-cell collides with complimentary antigen
B-cell engulfs antigen by endocytosis
B-cell binds to complimentary T -help cell
Activates B-cell, B-cell undergoes clonal expansion to B-memory-cells and plasma cells
Phagocytosis
Phagocyte detects pathogen by chemotaxis
Phagocyte engulfs pathogen via endocytosis
Pathogen is engulfed within a phagosome
Vesicle fuses with phagosome and releases its contents
Hydrolysing enzymes (lytic enzymes) hydrolyses bonds within the pathogen
Soluble products of the pathogen are used, some are released by exocytosis
B-memory cell
Cell that can differentiate into plasma cells
plasma cell
Cell that produces antibodies
Antibody structure
Light chain heavy chain, disulfide bridges, variable region and antigen binding site
Cell surface membrane structure + function
Phospholipid bilayer
Cholesterol
Integral proteins
Channel proteins
Carrier proteins
controls what enters and exits the cell
Nucleus
Structure + function
Contains genetic material of the cell
Nucleoplasm
Nucleolus
Site of transcription and DNA replication
contains chromosomes
SER
structure + function
Folded membranes - cristernae
Stores and synthesises lipids and carbohydrates
RER
structure + function
folded membranes - cristernae with ribosomes attached
Golgi apparatus
structure + function
Folded membranes -cristernae
Secretory vesicles pinch off from the cristernae
Add carbohydrates to proteins forming glycoproteins
Secrete carbohydrates
transport modify and package the lipids
Form lysosomes
Molecules labelled with their destination
Finished products are transported to the cell surface membrane and the contents are removed
Lysosomes
Structure and function
Bags of digestive enzymes Hydrolyse phagocytic cell
Completely break down dead cells (autolysis)
Exocytosis release enzymes to outside of the cell to destroy material
digest worn out organelles for the reuse if materials
Mitochondria
Double membrane
Inner membrane called the cristae
Site of aerobic respiration
Site of ATP production
DNA to code for proteins used in respiration
Ribosomes
Protein + rRNA
80s - Large ribosome (eukaryotic cells)
70s - smaller ribosome (prokaryotic, mitochondria and chloroplasts)
Site of protein synthesis
Vacuole
Filled with fluid surrounded by a single membrane (tonoplast)
Cells become turgid and therefore provide support
Homologous chromosomes
Two chromosomes that contain the same genes with possibly different alleles, one maternal chromosome and one paternal chromosome