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Endocrino > Pancreas > Flashcards

Pancreas Flashcards

1
Q

Glut 1

A

Constitutivo

Cerebro - Globulos rojos - Placenta - Tejido Adiposo - Riñon

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2
Q

Glut 2

A

En organos que censan la glucemia

Higado - Celulas beta - Riñon

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3
Q

Glut 4

A

Insulino dependiente

Tejido adiposo - Musculo esqueletico y liso

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4
Q

Hiperglucemiantes rapidos

A

Glucagon

Adrenalina

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5
Q

Hiperglucemiantes lentos

A
  • GH
  • Glucocort
  • HT
  • Eg y Pg
  • ACTH
  • hLP
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6
Q

Rcp simpatico alfa 2

A

Hiperglucemiante (inhibe celulas beta)

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7
Q

Rcp simpatico beta 2

A

Hipoglucemiante

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8
Q

Glucemia normal

A

70 - 110 mg%

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9
Q

Hormonas contrarreguladoras ¿Que son y cuales son?

A

Son aquellas hormonas cuya liberacion esta estimulada por la hipoglucemia

  • Glucagon
  • Adrenalina
  • Glucocort (cortisol)
  • GH
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10
Q

Estimulos para la insulina

A
  • Hiperglucemia
  • Arginina y Lisina
  • Ac grasos
  • Ach
  • Cortisol
  • Glucagon
  • Fructosa
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11
Q

Inhibidores de la insulina

A
  • SS

- Adrenalina

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12
Q

Efecto incretina

A

Potencian el efecto de la insulina

GIP y GLP-1

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13
Q

Efectos de la insulina

A

Me entro glucosa… Es el momento de sintetizar!

  • Glucogenogenesis
  • Glucolisis
  • Transporte de AAs
  • Via de las pentosas
  • Lipogenesis (estimula LPL)
  • Sintesis de Ac. grasos
  • Anabolica proteica
  • Traduccion y transcripcion del ADN
  • Aumenta actividad de la bomba sodio potasio
  • Inhibe glucagon
  • Inhibe NPY
  • Estimula sintesis de proteinas de la leche
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14
Q

Estimulos del glucagon

A
  • Hipoglucemia
  • AAs
  • Catecolam
  • Glucocort
  • GH
  • Ejercicio
  • Estres
  • CCK
  • Gastrina
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15
Q

Inhibidores de glucagon

A
  • Insulina
  • SS
  • CC
  • AG libres
  • Secretina
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16
Q

Efectos del glucagon

A

No tengo glucosa… Necesito liberar!

  • Glucogenolisis
  • Gluconeogenesis
  • Lipolisis
  • Cetogenesis
  • Proteolisis
  • Liberacion de GH
  • Liberacion de SS e Insulina
17
Q

Glucemia en ayuno de 8 horas

A

> 126mg% Repito estudio

110 - 125 mg% Glucemia alterada en ayuno. TTOG

18
Q

TTOG

A

< 140 mg% Normal
> 200 mg% Diabetico
140 - 190 mg% Intolerancia oral a la glucosa. Controlar

19
Q

Clinica de mielitus

A 
Poliuria
Polidipsia
Polifagia
Alteraciones del peso
Astenia
Prurito
20
Q

Diabetes tipo 1

A 
En jovenes
Autoinmune
Delgados
Insulinemia baja (ayuno cte)
Insulino dependientes
Cetoacidosis frecuente
21
Q

Diabetes tipo 2

A 
Adultos
Adquirida por down regulation de rcp de insulina
Gordos
Insulinemia alta
Cada vez requieren mas insulina

Endocrino (12 decks)

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