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Endocrino > Adrenal > Flashcards

Adrenal Flashcards

1
Q

Autosomica recesiva

  • Deficit de cortisol
  • Falta de feedback negativo
  • Aumenta ACTH

2 tipos

A

Hiperplasia suprarrenal congenita

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2
Q

Deficit de 21 hidroxilasa

A
  • No hay Aldosterona ni Cortisol
  • Aumentan los androgenos
  • Pierde Na

~ Virilizacion en mujeres con genitales ambiguos
~ Hiponatremia, deshidratacion, hipotension e hiperpotasemia

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3
Q

Deficit 11 beta hidroxilasa

A
  • La desoxialdosterona y la desoxicortisona son menos potentes pero tienen accion
  • Aumentan androgenos

~ Hipertension
~ Virilizacion en mujeres
~ Pubertad precoz

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4
Q

Enf de Addidon

A
  • Destruccion de cx por tuberculosis
  • Autoinmune
  • Perdida de NaCl y agua
  • Hiperpotasemia
  • Hemoconcentracion
  • Hipoglucemia
  • Debilidad
  • Alta pigmentacion (hipersecrecion de ACTH)
  • Hipotension
  • Anorexia
  • trastornos sexuales
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5
Q

Vasoconstriccion arterial

Vasoconstriccion venosa

A

Alfa 1 y 2 respect

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6
Q

Vasodilatacion arterial

A

Beta 2

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7
Q

Aumento de secrecion de insulina y glucagon

A

Beta

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8
Q

Disminucion secrecion insulina y glucagon

A

Alfa 2

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9
Q

Dilatacion pupilar

A

Alfa 1

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10
Q

Disminucion de la motilidad

A

Beta 2

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11
Q

Contraccion de esfinteres

A

Alfa 1

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12
Q

Lipolisis

A

Beta 1 2 3

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13
Q

Contraccion musc esqueletico

A

Beta 2

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14
Q

Aumento transmisión neuromusc

A

Alfa 1

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15
Q

Broncodilatacion

A

Beta 2

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16
Q

Aumento de renina

17
Q

Gluconeogenesis

18
Q

Glucogenolisis

A

Beta 2

Alfa 1

19
Q

Aumento de la frec y propiedades cardiacas

20
Q

Piloereccion

21
Q

Aumento de la calorigenesis

22
Q

Aumenta secrecion GH

23
Q

Metabolito del cortisol

24
Q

Que zonas regula la ACTH?

A

Fasciculada y reticular

25
Q

Zona fasciculada

A

Glucocorticoides

26
Q

Zona reticular

A

Androgenos

27
Q

Zona glomerular

A

Mineralocorticoides

28
Q

Metabolismo de catecolaminas

A

MAO y COMT te dan Ac. Vainillin Mandelico

29
Q

Deficit de 17 hidroxilasa

A

No hay Androgenos ni cortisol

  • Retencion de Na y H2O (hipertension)
  • HipoKalemia
30
Q

Quien hace el feedback del eje?

31
Q

Estimulos

A
  • ADH
  • Estres
  • Ag II
  • A/NA
  • Serotonina
  • Citoquinas proinflam
32
Q

Inhibidores

A
  • SS

- Glucocort exogenos

33
Q

Quien se encarga del estres agudo?

A

Cortisol y adrenalina

34
Q

Quien se encarga del estres cronico?

35
Q

Que sintetiza POMC?

A

ACTH
MSH
B endorfinas
CLIP

36
Q

Insuficiencia primaria

A

Disminuye cortisol y aumenta ACTH

Puede haber hiperpigmentacion

37
Q

Insuficiencia secundaria

A

Disminuyen cortisol y ACTH

No hay hiperpigmentacion

Endocrino (12 decks)

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