Pancreas Flashcards
Isle of Langerhorns
apart of endocrine pancreas
Acinar Cells
part of exocrine pancreas, produces digestive proenzymes and bicarbonate buffer
Bicarbonate Buffer
protects small intestine lining from acidic chyme, decreases pH of intestines
Lipase
digests lipids, activated by bile salts
Amylase
digests starch into disaccharides, secreted in active form
Protease
digests proteins to amino acids and small peptides
Insulin
51 amino acid peptide hormone, made by beta cells of pancreas, parasympathetic division (vagus nerve and Ach), glucose and amino acids from feed stimulate release
Glucagon
29 amino acid polypeptide hormone, alpha cells make it, neural and humoral factors (hormone), amino acids stimulate release
Exocrine Pancreas
makes digestive proenzymes, bicarbonate buffer, travel from pancreatic duct to duodenum of small intestine. Pancreatic proenzymes help digest food
Endocrine Pancreas
hormones, transported to target tissues by blood, mainly insulin and glucagon (aid in regulation of blood glucose)
Proteolytic Enzymes
Trypsinogen
Chymotrypsinogen
Proelastase
Procarboxypeptidate A and B
Tyrosine Kinase Insulin Receptor
transmembrane, insulin binding location on target tissue to initiate response
G-Coupled Protein Receptor
where glucagon binds on liver cells, initiates cellular signaling cascade, triggers metabolism of carbs, fats, proteins inside cell
Trypsinogen
activated to trypsin
Chymotrypsinogen
activated to chymotrypsin
Proelastase
activated to elastase
Procarboxypeptidase A and B
activated to Carboxypeptidase A and B