PAMs

Question 1

PAM stands for ?

It is ?

Answer 1

Positive Allosteric Modulators

They induce an amplification of a taste sensation

(in this case sweetness:)
•Small molecules that enhance receptor activity and sweetness perception
•Very effective at potentiating the sweetness of sweet compounds

Question 2

Ex of PAMs (4)

Answer 2

Sucralose modifier S2383 (Senomyx)
(Senomyx)
Sweetmyx SR96 (S9632)
Sweetmyx Flavor Ingredient

Question 3

Effect of Sucralose modifier S2383 (Senomyx)

Answer 3

6-22ppm halves the amount of sucralose required to produce an equivalent sweetness.

Question 4

Effect of (Senomyx)

Answer 4

Used at ppm levels as part of a flavour system to restore the desired taste profile of products in which sucrose (table sugar) has been reduced

Question 5

Effect of Sweetmyx SR96 (S9632)

Answer 5

Enhances the sweet taste of sucrose. At level of 26uM (10ppm) halves the amount of sucrose
required to produce an equivalent sweetness.

Question 6

Effect of Sweetmyx Flavor Ingredient

Answer 6

Enhances the sweet taste of sucrose and fructose. At a level of 10ppm halves the amount of sucrose required to produce an equivalent sweetness. At10ppm reduces the level of high fructose corn syrup by one third.

Question 7

Hesperetin

Found in?
effect?
Other properties?

Answer 7

Symrise: Patented for enhancing sweetness

Flavanone found in grapefruit, orange, lemons and apples. Can reduce the content of sugars such as sucrose, lactose, fructose and glucose by between 5 and 60% in the presence of around 100ppm hesperetin.

Cholesterol lowering properties. Protective against colon and other cancers