Palliative Prescribing Flashcards

1
Q

In palliative patients, what initial opioid prescription is recommended?

A

It is recommended that regular oral modified release or oral immediate release morphine, with oral immediate release morphine for breakthrough pain, is administered

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2
Q

What is the general advice when selecting the most appropriate breakthrough management?

A

It is generally advised that the same drug should be used for regular and breakthrough pain relief

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3
Q

Which administration route of breakthrough pain provides the fastest relief?

A

Nasal Sprays

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4
Q

What opioid is recommended in palliative patients with mild to moderate chronic kidney disease?

A

Oxycodone

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5
Q

Which three opioids are recommended in palliative patients with severe chronic kidney disease?

A

Alfentanil

Buprenorphine

Fentanyl

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6
Q

In palliative patients, with no co-morbidities, what initial dose of oral morphine is recommended?

A

It is recommended that a dose of 20-30mg of modified release oral morhpine is administered a day - with 5mg morphine for breakthrough pain

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7
Q

What is the recommendation when increasing the dose of opioids?

A

It should be increased by 30-50% at a time

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8
Q

How do we calculate the breakthrough dose of morphine?

A

We divide the daily dose of morphine by 6

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9
Q

How do we convert the dose of oral codeine to oral morphine?

A

We divide the dose by 10

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10
Q

How do we convert the dose of oral tramadol to oral morphine?

A

We divide the dose by 10

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11
Q

How do we convert the dose of oral morphine to oral oxycodone?

A

We divide the dose by 1.5

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12
Q

How do we convert the dose of oral morphine to subcutaneous morphine?

A

We divide the dose by 2

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13
Q

How do we convert the dose of oral morphine to subcutaneous diamorphine?

A

We divide the dose by 3

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14
Q

How do we convert the dose of oral oxycodone to subcutaneous diamorphine?

A

We divide the dose by 1.5

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15
Q

How much oral morphine equates to one transdermal fentanyl 12mcg patch?

A

30mg

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16
Q

How often should fentanyl patches be changed?

A

Every 3 days

17
Q

How much oral morphine equates to one transdermal buprenorphine 10mcg patch?

A

24mg

18
Q

What is the first line management option of agitation in palliative patients? What dose, route and frequency?

A

Haloperidol 0.5mg Two Hourly