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Year Five - Prescribing Safety Assessment > Adverse Drug Reactions > Flashcards

Adverse Drug Reactions Flashcards

1
Q

Which drug is known to cause acute intermittent porphyria?

A

Co-Trimoxazole

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2
Q

Which drug is known to cause agitation?

A

Cyclizine

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3
Q

Which three drugs are known to cause ankle oedema?

A

Angiotensin Receptor Blockers (ARBs)

Calcium Channel Blockers (CCBs)

Naproxen

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4
Q

Which two drugs are known to cause bradycardia?

A

Beta-Blockers

Digoxin

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5
Q

Which two drugs are known to cause circulatory collapse?

A

Isosorbide Mononitrate

Sildenafil

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6
Q

Which nine drugs are known to cause confusion?

A

Anticholinergic Drugs

Anticonvulsants

Antidepressants

Antipsychotics

Benzodiazepines (diazepam, temazepam, etc)

Corticosteroids

Metoclopramide

Opioids

Trazodone

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7
Q

Which two drug classes are known to cause constipation?

A

Antimuscarinics (tolteridone, etc)

Opioids

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8
Q

Which three drugs are known to cause candidiasis?

A

Amoxicillin

Clarithromycin

Corticosteroids

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9
Q

Which drug class is known to cause dehydration?

A

Diuretics

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10
Q

Which three drugs are known to cause diarrhoea?

A

Alendronic Acid

Magnesium Glycerophosphate

Proton Pump Inhibitors

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11
Q

Which drug is known to cause dry mouth?

A

Oxybutynin

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12
Q

Which two drug classes are known to cause dyspepsia?

A

Bisphosphonates - e.g. alendronic acid

Corticosteroids

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13
Q

Which seven drugs are known to worsen seizure control in epilepsy patients?

A

Ciprofloxacin

Levofloxacin

Aminophylline

Theophylline

Bupropion

Methyphenidate

Mefenemic Acid

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14
Q

Which drug class is known to cause erectile dysfunction?

A

Beta Blockers

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15
Q

Which drug is known to cause extra-pyramidal effects?

A

Metoclopramide

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16
Q

Which five drug classes are known to cause falls?

A

ACE Inhibitors

Antidepressants

Antimuscarnic Drugs - e.g. oxybutynin, etc

Benzodiazepines

Opioids

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17
Q

Which drug class is known to cause floppy iris syndrome?

A

Alpha Blockers - Tamsulosin

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18
Q

Which three drug classes are known to increase the risk of fractures?

A

Corticosteroids

GnRH Agonists

Proton Pump Inhibitors

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19
Q

Which three drugs are known to cause gastrointestinal bleeding?

A

Corticosteroids

NSAIDs

Bisphosphonates (alendrotnic acid, etc)

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20
Q

Which seven drugs are known to cause glucose intolerance?

A

Thiazide Diuretics

Corticosteroids

Antipsychotics

Tacrolimus

Ciclosporin

Interferon Alpha

Nicotinic Acid

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21
Q

Which drug class is known to cause a slight glucose intolerance, and should therefore be administered cautiously in diabetics?

A

Beta-Blockers

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22
Q

Which drug class is known to cause haematemesis?

A

NSAIDs

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23
Q

Which three drug classes are known to cause heartburn?

A

Antimuscarinic Drugs - e.g. tolterodine

Bisphosphonates - e.g. alendronic acid

Calcium Channel Blockers

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24
Q

Which drug is known to cause hearing difficulties?

A

Gentamicin

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25
Q

Which five drugs are known to exacerbate heart failure?

A

Thiazolidinediones

NSAIDs

Corticosteroids

Flecainide

Verapamil

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26
Q

Which NSAID is an exception to the rule of heart failure exacerbation?

A

Low Dose Aspirin

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27
Q

Which drug is known to cause hepatic impairment?

A

Amiodarone

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28
Q

Which two drug classes are known to cause hyperglycaemia?

A

Corticosteroids

Thiazide Diuretics

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29
Q

Which three drugs are known to cause hyperkalaemia?

A

ACE Inhibitors

Aldosterone Inhibitors

Ciclosporin

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30
Q

Which drug class is known to cause hypoglycaemic unawareness?

A

Beta-Blockers

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31
Q

Which two drugs are known to cause hypokalaemia?

A

Amiodarone

Thiazide Diuretics

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32
Q

Which three drugs are known to cause hyponatraemia?

A

Bendroflumethiazide

Citalopram

Indapamide

33
Q

Which eight drugs are known to cause a decrease in INR levels?

A

SCRAP GP

Sulphonylureas

Carbamazepine

Rifampicin

chronic Alcohol intake

Phenytoin

Griseofulvin

Phenobarbitone

34
Q

Which fourteen drugs are known to cause an increase in INR levels?

A

SICKFACES.COM

Sodium Valproate

Isoniazid

Cimetidine

Ketoconazole

Fluconazole

Acute Alcohol Intake/Allopuronol/Amiodarone

Chloramphenicol

Erythromycin

Sulfonylureas

Ciprofloxacin/Clarithromycin

Omeprazole

Metronidazole

35
Q

Which drug is known to cause iron deficiency anaemia?

36
Q

Which drug is known to cause jaundice?

A

Flucloxacillin

37
Q

Which drug is known to cause lactic acidosis?

38
Q

Which drug is known to cause leucopenia?

A

Methotrexate

39
Q

Which five drugs are known to cause medication overuse headaches?

A

Aspirin

Codeine

Ergotamine

Paracetmaol

Triptans

40
Q

Which drug is known to cause myositis?

41
Q

Which four drugs are known to cause oculogyric crisis?

A

Haloperidol

Metoclopramide

Phenothiazines

Risperidone

42
Q

What are the three features of oculogyric crisis?

A

Agitation

Restlessness

Involuntary Upward Deviation of the Eyes

43
Q

What is the first line management option of oculogyric crisis?

A

Procyclidine

44
Q

What are the four drugs which cause pancreatitis?

A

Azathioprine

Corticosteroids

DDP-4 Inhibitors - ‘gliptin’

GLP-1 Agonists - ‘tide’

45
Q

Which drug class is known to exacerbate peripheral vascular disease - such as ischaemic leg ulcers?

A

Beta-Blockers

46
Q

Which drug class is known to cause orthostatic hypotension?

A

Alpha Blockers - e.g. ‘sin’

47
Q

Which three drugs are known to cause polymorphic ventricular tachycardia - such as Torsades de Pointes?

A

Citalopram

Fluconazole

Ranolazine

48
Q

Which seven drugs are known to exacerbate psoriasis?

A

NSAIDs

ACE Inhibitors

Beta-Blockers

Lithium

Chloroquine

Hydroxychloroquine

Infliximab

49
Q

Which five drugs are known to cause pulmonary fibrosis?

A

Cytotoxic Agents

Anti-Rheumatoid Drugs

Dopamine Receptor Agonists

Amiodarone

Nitrofurantoin

50
Q

Which drug is known to cause retinopathy?

A

Hydroxychloroquine

51
Q

Which drug is known to cause sleep disturbances?

A

Mirtazapine

52
Q

Which drug is likely to cause tendonitis?

A

Quinolone Antibiotics - ‘floxacin’

53
Q

Which four drugs are used to treat tuberculosis?

A

RIPE

Rifampicin

Isoniazid

Pyrazinamide

Ethambutol

54
Q

What are the three side effects of rifampicin?

A

‘R = Red Secretions’

Flu-Like Symptoms

Hepatitis

Orange Secretions

55
Q

What are the three side effects of isoniazid?

A

‘I = I’m so numb’

Peripheral Neuropathy

Hepatitis

Agranulocytosis

56
Q

In order to prevent the side effect of peripheral neuropathy with isoniazid, which drug can be administered?

A

Pyridoxine (Vitamin B6)

57
Q

What are the four side effects of pyrazinamide?

A

Hyperuricaemia (Gout)

Arthralgia

Myalgia

Hepatitis

58
Q

What is the side effect of ethambutol?

A

‘E = Eye Issues’

Optic Neuritis

59
Q

Which two drug classes are likely to cause vomiting?

A

GLP-1 Analogues - ‘tide’

Macrolide Antibiotics - ‘mycin’

60
Q

Which nine drugs are known to cause urinary retention?

A

Alcohol

Alpha-Adrenoreceptor Agonists

Anticholinergics

Antihistamines

Benzodiazepines

Calcium Channel Blockers

NSAIDs

Opioids

Tricyclic Antidepressants

61
Q

Which two drug classes commonly result in the adverse effect of hypoglycaemia?

A

Insulin

Sulphonureas

62
Q

Which five drug classes commonly result in the adverse effect of hyperglycaemia?

A

Antipsychotics

Beta-Blockers

Steroids

Tacrolimus

Thiazides

63
Q

Which seven drug classes commonly result in the adverse effect of constipation?

A

Anticholinergics

Antiemetics

Antiepileptics

Calcium Channel Blockers

Diuretics

Iron

Opioids

64
Q

Which six drug classes commonly result in the adverse effect of diarrhoea?

A

Antacids

Antibiotics

Colchicine

Laxatives

Metformin

Protein Pump Inhibitors

65
Q

Which two drug classes commonly result in the adverse effect of urinary retention?

A

Anticholinergics

Opoids

66
Q

Which four drug classes commonly result in the adverse effect of urinary incontinence?

A

Alpha-Blockers

Anticholinesterase Inhibitors

Clozapine

Diuretics

67
Q

Which three drug classes commonly result in the adverse effect of confusion?

A

Anticholinergics

Opioids

Sedatives

68
Q

Which seven drug classes commonly result in the adverse effect of falls?

A

Antidepressant

Antihypertensives

Antiepileptics

Antipsychotics

Benzodiazepines

Opioids

Parkinson’s Drugs

69
Q

Which drug class commonly results in the adverse effect of gout?

70
Q

Which four drug classes commonly result in the adverse effect of osteoporosis?

A

Luteinising Hormone Releasing Hormone Agonists

Proton Pump Inhibitors

Steroids

71
Q

Which four drug classes commonly result in the adverse effect of hypertension?

A

Mirabegron

NSAIDs

Oral Contraceptives

Steroids

72
Q

Which two drug classes commonly result in the adverse effect of hypercholesterolaemia?

A

Steroids

Thiazides

73
Q

Which four drug classes commonly result in the adverse effect of hypokalaemia?

A

Loop Diuretics

Salbutamol

Steroids

Thiazides

74
Q

Which six drug classes commonly result in the adverse effect of hyperkalaemia?

A

ACE Inhibitors

Angiotensin Receptor Blockers (ARBs)

Blood Transfusion

Low Molecular Weight Heparin (LMWH)

Potassium Sparing Diuretics

Unfractioned Heparin

75
Q

Which five drug classes commonly result in the adverse effect of hyponatraemia?

A

Carbamazepine

Opioids

Protein Pump Inhibitors (PPIs)

Selective Serotonin Reuptake Inhibitors (SSRIs)

Tricyclic Antidepressants (TCAs)

76
Q

Which two drug classes commonly result in the adverse effect of hypernatraemia?

A

Demeclocycline

Lithium

77
Q

Which two drug classes commonly result in the adverse effect of hypotension?

A

Beta-Blockers

Calcium Channel Blockers

78
Q

Which two drug classes commonly result in the adverse effect of oral candidiasis?

A

Antibiotics

Immunosuppressants

Corticosteroids

79
Q

Which drug class commonly results in the adverse effect of euglycemic diabetic ketoacidosis?

A

Sodium Glucose Co-Transporters (-glifozins)

Year Five - Prescribing Safety Assessment (8 decks)

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