Palliative and Geriatric medicine Flashcards
How do you convert from oral to subcutaneous morphine dosing?
Divide by 2
What is a standard dosing of morphine for patients with progressive disease and no comorbidities?
15mg MR morphine PO BD
5mg Oromorph PO PRN
How much should the dose of opioids be increased by in thesubsequent dose?
30-50%
What is the conversion factor from codeine to morphine to tramadol?
x10 x10
WHat is the conversion factor from oral mophine to diamorphine?
Divide by 3
What is the first choice of prescription for agitation and confusion in a pre-terminal and terminal patient?
Pre terminal - Haloperidol PO
Terminal - Midazolam SC
What interventions does metastatic bone pain typically respond to?
Strong opioids
Bisphosphonates
Radiotherapy
What is the difference in side effect profile between oxycodone and morphine?
Oxycodone causes less sedation, vomiting and pruritis but more constipation
How much of the daily dose should the breakthrough dose of morphine be?
1/6th
How much morphine is 12mcg/hr fentanyl patch equivalent to?
30mg daily
What opioids are safest for use in patients with severe renal impairment?
Fental and buprenorphine - as they are not renally excreted
What medications can be used for hiccups in palliative care?
Chlorpromazine
Haloperidol
What should be added to the syringe driver in a patient with malignant bowel obstruction?
Hyoscine butylbromide
What is the mechanism of action of Donepezil?
Acetylcholinesterase inhibitor
Which antipsychotic is contraindicated in PD patients>
Haloperidol