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Pharm III > Pain relief > Flashcards

Pain relief Flashcards

1
Q

salicylates

A

nonacetylated salicylates NSAID

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2
Q

acetyl salicylic acid

A

Aspirin NSAID

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3
Q

celecoxib

A

COX2 selective NSAID

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4
Q

meloxicam

A

COX2 preferential NSAID

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5
Q

diclofenac

A

nonselective NSAIDs

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6
Q

diflunisal

A

nonselective NSAIDs

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7
Q

etodolac

A

nonselective NSAIDs

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8
Q

flubiprofen

A

nonselective NSAIDs

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9
Q

ibuprofen

A

nonselective NSAIDs

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10
Q

indomethacin

A

nonselective NSAIDs

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11
Q

ketoprofen

A

nonselective NSAIDs

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12
Q

ketorolac

A

nonselective NSAIDs

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13
Q

nabumetone

A

long 1/2 life nonselective NSAIDs

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14
Q

naproxen

A

nonselective NSAIDs

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15
Q

oxaprozin

A

long 1/2 life nonselective NSAIDs

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16
Q

piroxicam

A

long 1/2 life nonselective NSAIDs

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17
Q

sulindac

A

nonselective NSAIDs

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18
Q

tolmetin

A

nonselective NSAIDs

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19
Q

which NSAID is IM?

A

ketorolac

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20
Q

what NSAID should not be used for gout?

A

tolmentin

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21
Q

what NSAID should not be used for inflammation?

A

toradol

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22
Q

acetaminophen

A

APAP

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23
Q

antidote for APAP (acetaminophen)

A

N-actylcysteine

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24
Q

gabapentin

A

neuropathic pain reliever (DM neuropathic pain, post-herpetic neuralgia, or diffuse pain syndromes like fibromyalgia)

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25
Q

pregabalin

A

neuropathic pain reliever (DM neuropathic pain, post-herpetic neuralgia, or diffuse pain syndromes like fibromyalgia)

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26
Q

amitriptyline

A

migraines & DM neuropathy

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27
Q

methyl salicylate

A

wintergreen oil a topical pain reliever

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28
Q

capsaicin

A

topical pain reliever red pepper derivative for post-herpetic neuralgia or arthritic pain

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29
Q

lidocaine 5% patch

A

topical

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30
Q

lidocaine/prilocaine

A

topical

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31
Q

visceral pain?

A

narcotics (full or partial agonists, avoid mixed agonists)

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32
Q

mild pain?

A

acetaminophen

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33
Q

mild inflammatory pain?

A

NSAIDs

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34
Q

neuropathic pain?

A

mild: topical like capsaicin
moderate: amitryptyline, gabapentin, or pregabalin

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35
Q

moderate to severe acute or chronic pain?

A

full agonists

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36
Q

morphine

A

full narcotic agonist

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37
Q

methadone

A

full narcotic agonist (5 day 1/2 life)

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38
Q

fentanyl

A

full narcotic agonist

IV, intrathecal, epidural, transdermal, intranasal and oral transmucosal formulations

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39
Q

hydromorphone

A

full narcotic agonist (IV, rectal, PO)

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40
Q

oxycodone

A

full narcotic agonist (PO only)

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41
Q

oxymorphone

A

full narcotic agonist (IV & PO)

42
Q

meperidine*

A

full narcotic agonist (strong with anticholinergic effects) use for 24-48 hr for acute pain

43
Q

codeine

A

converted to morphine by CYP2D6

44
Q

hydrocodone

A

Synthetic opioid that is metabolized to hydromorphone

45
Q

tapentadol

A

full agonist NE reuptake inhibitor narcotic

46
Q

tramadol

A

Centrally-acting opioid agonist

47
Q

buprenophine

A

partial agonist narcotic

48
Q

buprenorphine & naloxone

A

partial agonist narcotic

49
Q

buprenophrine ER

A

partial agonist narcotic

50
Q

butorphanol*

A

mixed opioid agonist/antagonist narcotic

51
Q

nalbuphine

A

mixed opioid agonist/antagonist narcotic

52
Q

pentazocine

A

mixed opioid agonist/antagonist narcotic

53
Q

Dextromethorphan

A

OTC cough suppressant

related to narcotics

54
Q

Diphenoxylate

A

diarrhea

55
Q

naloxone

A

narcotic antidote/antagonist

56
Q

Naltrexone

A

narcotic antidote/antagonist

57
Q

Nalmefene

A

narcotic antidote/antagonist

58
Q

Buprenorphine/naloxone

A

addiction narcotic antidote/agonist/antagonist

59
Q

dronabinol

A

Cannabinoids

60
Q

nabilone

A

Cannabinoids

61
Q

LSD

A

hallucinogens

62
Q

Mescaline

A

hallucinogens

63
Q

psilocybin

A

hallucinogens

64
Q

PCP

A

hallucinogens

65
Q

ketamine

A

hallucinogen/anesthetic

66
Q

nitrates, ketones, hydrocarbons, amyl nitrates

A

inhalants

67
Q

flumazenil

A

benzo antagnoist/antidote

68
Q

clonidine

A

opiod withdrawl alleviative

69
Q

methadone

A

long 1/2 life substitute for opioid withdrawal

70
Q

curare

A

nondepolarizing neuromuscular blocker

71
Q

tubocurarine

A

nondepolarizing neuromuscular blocker

competitive antagonist

72
Q

atracurium

A

nondepolarizing neuromuscular blocker

competitive antagonist

73
Q

pancuronium

A

nondepolarizing neuromuscular blocker

competitive antagnoist

74
Q

acetylcholinesterase inhibitors

A

reverse effect of non depolarizing neuromuscular blocker by increasing ACh concentrations

75
Q

succinylcholine

A

depolarizing neuromuscular blocker

76
Q

neostigmine

A

acetylcholinesterase inhibitors

77
Q

pyridostigmine

A

acetylcholinesterase inhibitors

78
Q

diazepam*****

A

spasmolytics/benzo

any disorder

79
Q

baclofen*****

A

spasmolytics

80
Q

tizanidine**

A

spasmolytics

spaticity from cerebral or spinal injury

81
Q

dantrolene***

A

spasmolytics

spasms (CNS or spinal cord) and malignant hyperthermia

82
Q

gabapentin/pregabalin*

A

spasmolytics

MS

83
Q

orphenadrine***

A

spasmolytics

84
Q

carisoprodol**

A

spasmolytics

85
Q

cyclobezaprine**

A

spasmolytics

86
Q

metaxalone**

A

spasmolytics

87
Q

methocarbamol***

A

spasmolytics

88
Q

what drugs precipitate Serotonin syndrome?

A 
SSRIs
second generation antidepressants
MOAIs
linezolid
tramadol***
meperidline***
fentanyl***
ondansetron
sumatriptan
MDMA***
LSD***
st. john's wort
ginseng
89
Q

what drugs precipitate neuroleptic malignant syndrome?

A

D2-blocking antipsychotics

90
Q

what drugs precipitate malignant hyperthermia?

A

volatile anesthetics and succinylcholine

91
Q

Sx of serotonin syndrome

A 
onset in hours:
hypertension
hyperreflexia
tremor
clonus
hyperthermia**
hyperactive bowel sounds
diarrhea
mydriasis**
agitation
coma
92
Q

therapy for serotonin syndrome

A

sedation (benzos), paralysis, intubation, and ventilation

93
Q

clinical presentation of neuroleptic malignant syndrome?

A 
Onset in 1-3 days:
acute severe parkinsonism
hypertension
hyperthermia**
normal/reduced bowel sounds
94
Q

treatment for neuroleptic malignant syndrome?

A

diphenhydramine
cooling
sedation with benzos

95
Q

sx of malignant hyperthermia?

A 
Onset in minutes:
hyperthermia**
muscle rigidity
hypertension
tachycardia
96
Q

treatment for malignant hyperthermia?

A

dantrolene

cooling

97
Q

methocarbamol

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

98
Q

cyclobenzaprine

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

99
Q

orphenadrine

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

100
Q

carisoprodol

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

101
Q

metaxalone

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

102
Q

methocarbamol

A

relief of acute muscle spasm caused by tissue trauma or strain NOT for spasm from spinal cord or brain

Pharm III (5 decks)

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