Pain Physiology Flashcards
The transfer of energy from one form to another (starts at point of injury)
Transduction
Impulse travels length of axon
Transduction
The process of alterations in the pain signals along the transmission pathway of pain
Modulation
Order of nociception
Transduction -energy starts (action potential)
transmission
Perception
Modulation
Impulses transmitted, via the spinophthalmic tract to the brainstem and synapse in the thalamus, and the medulla
Perception
Sensory fibers
Transmission of pain signals
He’s sending signals from Neuro transmitters block or partially blocked transmission of pain impulses to mitigate pain
Modulation
Things that may modulate pain
Endogenous opioids
Serotonin
Norepinephrine
Gamma aminobutyric acid (GABA)
Acetylcholine
Oxytocin
Traumatic injury and external stimulus convert to electrical signal that patient can perceive as pain
Transduction
Unrelieved pain in pregnancy can cause the release of catecholamines that can result in:
Preterm labor - by releasing stress hormones that can cause uterine irritability and preterm labor
After undergoing a lobectomy for lung cancer unrelieved pain can cause a cascade of events such as
Increased amounts of cortisol, increased catecholamines, increased glucagon, growth hormone antidiuretic hormone (ADH), and decrease and insulin production. The endocrine system regulates metabolic activities and releases hormones, which regulate various functions int he body while maintaining homeostasis. Unrelieved pain produces stress response as noted. The end result is catabolism - breakdown of nutrients to produce energy.