Pain part 2 Flashcards
what are skeletal muscle relaxants and examples
act predominantly within the CNS to relieve pain associated with skeletal muscle spasms
methacarbamol
chlorzoxazone
orphenadrine
methocarbamol MOA
unknown
causes skeletal muscle relaxation
doesnt work directly on muscle
indication for methocarbamol
treat acute, painful, musculoskeletal muscle spasms
methocarbamol onset and use
12-24 hours
use limited due to side effects
orphenadrine indication
treat painful muscle spasms due to acute musculoskeletal conditions
orphenadrine onset of action and use
more than 24 hours
use limited due to side effects
hwo does chlorzoxazon work
central acting properties doesnt act on the muscles
decreases muscle spasm to decrease pain and increase mobility in musculoskeletal conditions
onset and use of chlorzoxazone
12-24 hours
nto used to side effect of hepatotoxicity
common side effects of skeletal muscle relaxants
drowsiness
dizzines
headache
light headed
common contraindications of skeletal muscle relaxants
pregnancy
anticholinergic activity therefore gluacoma, porstate hypertrophy, arrhythmias etc
side effect of methocarbamol and chlorzoxazone
urine discoloration
metho - black, blue, green
chlor - orange, purple, red
skeletal muscle relaxant drug interactions
other Ach agents CNS depressants MAO inhibitors alcohol all CMS depressants
difference between anesthetic and analgesic
analgesic raises pain threshold at terminal nerve endings
anesthetic blocks pain receptors to numb the area
whats the counterirritant effect of topical
stimulates cutaneous sensory receptors causes you to feel that sensation instead of the more intense pain
known as paradoxical pain
adjuvant therapy
placebo effect from the odor or cooling/warming effect
analgesic with cooling effect
methyl salicylate
capcaicin
trolamine salicylate
analgesic wiht cooling effect
menthol
camphor
which product has no odor
trolamine salicylate
advice for external analgesic use
dont apply to wounds or damaged skin dont bandage avoid contact with eyes not for children under 2 dont use more than 4 times a day dont apply heat with it
avoid use of methyl salicylates and trolamine salicylate in
people taking anticoagulants
allergic to salicylates
caution for salycylate sensitive asthmatics
are external analgesics any good
lack scientific evidence
more just a placebo due to the subjective nature of pain
doesnt alter underlying process more symptomatic relief or a distraction
what is tachyphylaxis and what does it occur in
effect diminishes with repeated applications
capsaicin
capsaicin MOA
depletion of substance P which normally allows the transmission of pain impulses in sensory neurons
reduces the pain not the inflammation
onset of capsaicin
pain relief in 14 days but can be delayed by 4-6 weeks
indication for capsaicin
osteoarthritis pain
postherapeutic neuralgia
low back pain
specific instructions for capsaicin
application less than 3 times a day may not provide relief and may cause the initial burning sensation to persist
continued application for 3-4 weeks need for optimal response, burning sensation will diminish
discontinue if doesnt improve in 28 days