Pain Modulation with Electrotherapy Flashcards
Gate Control Theory
Uses a-Betas to block C fibers
- C and A-delta inhibit/block inhibitory interneurons
- a-Beta fibers activate inhibitory interneurons
- Theory is that e stim activates inhibitory interneurons to block fibers from going to the brain
What is Stimulation Produced Analgesia
- Stimulation of the Periaqueductal gray region produces profound, selective analgesia
- Not associated with general inhibition of afferent input
- Can still respond to touch, pressure and temperature
How does stimulation produced analgesia work?
- Descending projections block the output of neurons from laminae I and V via direct and indirect inhibitory actions.
- They also interact with endogenous opioid containing circuits in the brain
Endogenous Opioids
- Manufactured by the brain
- Bind to opioid receptors distributed widely in the CNS, but are particularly concentrated in areas that process nocicepetive information (PAG, raphe nuclei and dorsal horn)
- we are trying to get opioids to bind to receptor sites to decrease sensation of pain
Which is the better pain control theory for chronic pain?
Stimulation Produced Analgesia
What nerve fibers are recruited with high frequency TENS
large diameter, superficial cutaneous nerve fibers
(sensory-level TENS)
High frequency TENS parameters
- Frequency: 50-100 + pps
- Amplitude: Perceptible “tingling”
- Phase duration: low (<150 microsec)
- Treatment time: 30 mins
- Analgesia time:: minimal residual effect
Low Frequency TENS
- Produces a visible muscle contraction
- A.k.a. low rate TENS and motor TENS
- Some “acupuncture-like TENS” is based on the same principle
- Supported by endogenous opiate mode of pain modulation
Low frequency TENS parameters
- Frequency: 2-4 pps
- Amplitude: Strong visible contraction
- Phase duration: > 150 microsec (200-300)
- Treatment time: 30-45 min
- Analgesia time: hours
- passive treatment
Noxious level stimulation
- A.k.a. hyperstimulation
- Can be performed in a remote site
- Endorphin mediated mechanism
- May get motor nerve stimulation, but often
applied to area with minimal motor nerve
fibers - Point stimulation (right over area that hurts)
Noxious level stimulation parameters
- similar to motor level stimulation except:
- phase duration is long ( up to 1 msec)
- treatment time is seconds to minutes
Comparison - Conventional
- higher frequency
- low intensity
- short phase duration
- moderate treatment time
- minimal carry over
Comparison - Motor/Noxious level
- lower frequency
- High intensity
- Long phase duration
- Long/short treatment time
- long carry over
Frequency
- Abeta few synapses, myelinated –> moves fast –> high frequency
- SPA or opioid modulation need time to build up chemicals –> no need for high frequency; also, higher frequency –> stronger motor contraction (not desirable)
Phase duration
Need longer phase duration to recruit motor nerves and very long PD to stimulate areas related to noxious nociceptors such as C-fibers