Pain, documentation, disablement Flashcards
substance P
transmission of pain- producing impulses, makes things less comfortable
acetylcholine
responsible for transmitting motor nerve impulses. PNS and CNS
norepinephrine
causes vasoconstriction, underlies “fight or flight” response
enkephalins
reduce pain perception by bonding to pain receptors
endorphins
morphine-like neurohormone, thought to increase pain threshold by bonding to pain receptors
serotonin
substance that causes local vasodilation and increase permeability of capillaries
afferent pathways
first order neuron
second order neuron
third order neuron
first order neuron
connects to periphral sensory receptor and projects info to DGR in spinal cord
-Aα=fastest, thick myelin, muscle spindle, GTO
-Aβ=fast, thick myelin, light touch, vibration, hair deflection
large diameter afferent
-Aδ=slow, thin myelin, sharp pain, touch, temp, pressure
-C=slowest, no myelin, dull and diffuse pain, touch, intense pressure, extreme temp
small diameter
second order neuron
cell body located in DGR, crosses midline and ascends to the thalamus
third order neuron
cell boy in the thalamus
nociceptors
nerve endings that are sensitive to painful stimuli
- Aδ and C fibers
- noxious pain
superficial sensory receptors
- mechanoreceptors: pressure, skin, stretch, and touch. meissner’s & pascinian corpuscles
- thermoreceptors: hold and cold receptors
- nociceptors: free nerve endings, pain
deep sensory receptors
- proprioceptors: (GTO, muscle spindles) changes in muscle length, joint position and vibration, joint end range
- nociceptors: free nerve endings, pain
- mechanoreceptors: change in muscle length and tension, ligamentous deformation
paleospinothalamic tract
- carries “slow pain”
- order of transmission: nociceptor, first order neuron (c fiber) to laminae II & III
neospinothalamic tract
- carries “fast pain”
- nociceptor (skin, soft tissue, periosteum), first order neuron (Aδ) to DGR
thalamus
area of the brain where pain is first identified and sorted
pain perception is influenced by…
physical, chemical, social, psychological
pain control theories
- gate control theory
- central biasing theory
- endogenous opiates theory
gate control theory
- considered ascending pain control mechanism
- what do you do when your elbow hurts?
- located in dorsal horn
- activate more Aβ fibers= more active, gate closes
- C fibers more active, gate opens (more pain is felt)
descending pain modulation
transmit impulses from the brain
- release of enkephalins and serotonin inhibit ascending neurons
periaqueductal gray (PAG)
receives input from the cortex, projects to rap he nucleus and activates neurons, then to the DRG and releases endogenous opiate called enkephalin
raphe nucleus
brainstem, releases serotonin to rest of the brain
central biasing theory
descending neurons are activated, causes release of enkephalins and serotonin to inhibit pain
endogenous opiates theory
release of enkephalins from pituitary gland into spinal fluid
- block ascending nerve impulses