Pain and Anxiety Flashcards

1
Q

Basic behavioural management strategies

A
Tell, show, do
Positive distraction - music
Relaxation 
Systemic desensitisation - d=gradual acclimatisation 
Hyponosis 
Advanced behavioural - psychology
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2
Q

Ideal sedation agent

A
Rapid onset 
Predictable action/duration 
Low incidence of side effects 
Simple to administer 
Rapid recovery 
Rapid metabolism/excretion
Sedation guidelines:
Poswillo report (1990, DoH)
A Concious Decision (2000, DoH)
Standards for Concious Sedation in the Provision of Dental Care - The Dental Faculties of the RCS and RCA (2015)
SDCEP - Concious sedation in dentistry
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3
Q

Oral sedation

A

Oral premedication at home:
Diazepam 2-5mg morning of
Temazepam 10mg night before - helps pt sleep as well
Ask GMP for advice/prescribe

Oral premedication in surgery:
Temazepam 10-20mg/10mg Midazolam, with monitoring

Oral sedation is - simple to administer, predictable action/duration, low incidence of side effects

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4
Q

Inhalation sedation

A
Requires specialist surgery/techniques/training 
Good for children 
Patent nasal airway 
Minimal intervention
Analgesic 
Hazards of chronic exposure 

IHS is: predictable action/duration, rapid onset, rapid metabolism/excretion, rapid recovery, simple to administer, low incidence of side effects

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5
Q

Intravenous sedation

A
With pulse oximeter monitoring 
With midazolam - titrated as needed 
Anticonvulsant 
Muscle relaxant 
Anterograde amnesia 
Good 20-30 mins sedation 
Minor respiratory/cardio depression 
No analgesic effects 
Side effects:
Over sedation 
Cardio depression 
Respiratory depression 
Tolerance 
Sexual fantasy 

IV sedation is: rapid onset, predictable duration, low incidence of side effects, rapid recovery, simple to administer

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6
Q

Minimal sed vs mod sed vs deep sed

RAVC

A

Minimal sed - normal response to verbal commands, airway unaffected, ventilation unaffected, cardiovascular unaffected

Mod sed - purposeful response to verbal or tactile stimulation, airway maintained w/o intervention, ventilation adequate, cardiovascular usually maintained

Deep sed - purposeful response following repeated or painful stimulation, airway may require intervention, ventilation may be inadequate, cardio usually maintained

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7
Q

Blood pressure determined by:

A

2 main components:
CO and SVR

CO: amount of blood ejected by heart per min - ave = 5L/min
Determined by HR and SV
HR between 50-180 has little effect
SV affected by - anaethetic drugs, dehydration/blood loss, ischaemic HD/HF

SVR: systemic vascular resistance. Mainly due to arterioles. Constriction = increased SVR, increased BP
Dilation = decreased SVR, low BP
SVR decreased by: sedative drugs, anaphylaxis, sepsis/infection

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8
Q

Acute and chronic BP control

A

Acute:
Baroreceptors in aortic arch and internal carotids
Send signals to brain stem
ANS alters rate and strength of heart contraction and constriction of BVs

Chronic:
Renin-angiotensin system
Aldosterone hormone
Chronic regulation of blood Na and body fluid retention

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9
Q

Midazolam:

Method of action, dose, reversal

A

Benzodiazepine - binds to benzo binding site and GABA binds to GABA binding site and activates opening of receptor channels causing influx of Cl- ions into cell, decreasing ability to initiate AP = sedative effect

Usual conc 5mg/ml
IV for moderate sedation
Onset 1-3 mins
Peak 5-7 mins
Duration 20-30 mins
Titre until desired end point e.g. slurred speech
Half life 1-2.8 hours. Increased 1/2 life if elderly, other meds, sepsis, poor renal function

Initial dose = 2.5mg over 2 mins 
Wait 2 mins for effect 
Subsequent doses 1mg
Usually no more than 5 total 
Cautions - decrease initial dose to 1.5mg in elderly and if pre-med given, then decrease dose by 1/3rd
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10
Q

Opiates e.g. Fentanyl

A
Opiates for analgesia but can have sedative effect at higher doses
Fentanyl:
Man made synthetic opiate
Analgesia and sedation 
Onset 1-2 mins
Peak 10-15 mins 
Duration 30-60 mins 
Dosing - 25mcg (0.5ml) bolus up to 200mcg max 

+ analgesia as well as sedation
+ fast onset
+ short duration action

  • hypotension and bradycardia
  • resp depression
  • nausea and vomiting
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11
Q

Pulse oximetry

A

Way of measuring O2 sats
2 diodes - light emitting and photodetector. Emits light into nail bed capillaries and light reflected back is picked up and calculated as % o2 saturation (Ho2 has diff absoprtion of light to xHo2 blood)

Limitations:
Ambient light 
Movement 
Cold peripheries - cause vasoconstriction, less blood flow into nail capills 
Nail varnish/false nails
Measurement lag - 30-60 seconds

Capnography - detects exhaled CO2 in breath via nasal prongs. Pt must be breathing through nose

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12
Q

Upper airway obstruction

A

Sedation decreases muscle tone of muscles in pharynx
Leading to pharyngeal collapse - tongue falls against back wall of pharynx
Total or partial airway obstruction

Signs of airway obs:
Snoring
Stridor 
Drop in O2 sats 
Loss of CO2 trace 
Seesaw respiration
Management:
Supplementary O2
Careful titration of sedation 
Airway opening maneuvers - jaw lift, chin lift
Airway adjuncts
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13
Q

Hypoventilation

A

Sedation also sedate resp centres in brain
Reduce receptor sensitivity to CO2
Leading to reduced resp rate or complete cessation breathing
CO2 level can build up leading to necrosis

Detection: monitoring of resp rate, drop in o2 sats

Mgt: reversal with Flumazenil for midaz or Naloxone for fenty
Self inflating ambubag for assisted ventilation

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14
Q

Hypotension

A

Sedative drugs can cause vasodilation
Some drugs decrease strength of heart contractions
Dose related - titre little by little and if elderly or existing heart condition, reduce by 1/3rd
More likely to occur in elderly and those with existing cardiovascular disease

Txt: prevention better than cure - if dehydrated, recent heart attack (6mo), long bleeding time, consider procedure elsewhere
Stop administering agent
Place pt head down feet elevated
IV fluids may be required

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15
Q

Cardiac arrhythmia / cardiac arrest

A

Multi factorial aetiology
May be precipitated by adrenaline in LA
More likely in elderly and those with CVS disease
Raised blood co2 levels also increase risk

Txt: call for expert help, advanced life support algorithms

Cardiac arrest - worst complication. Prevent by doing above. If high risk - refer. If suspect going from mod to deep sedation then wind down
Basic life support

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16
Q

Advantages of IV sedation

A
Given remote from operating site 
Excellent amnesia 
Mouth breathing not important
Given as single dose
No pollution of surrounding environment 
Rapid onset 
Patient cooperation less important 
Sedation attained pharmacologically
17
Q

Disadvantages of IV sedation

A

No clinically useful analgesia
Pre and post op instructions must be followed
Sexual fantasies
Occasional disinhibition effects
Laryngeal reflexes obtunded for short period
Overdose can lead to profound respiratory depression

18
Q

Pt assessment

A

Must justify why IV sedation over another technique e.g. time and TLC, LA, psychotherapy, hypnosis, acupuncture, IHS, oral sed, GA
MH
ASA score
DH
SH - escort, post-op care, work, transport
Physical assessment - colour, pulse, respiration, arterial o2 sat, BP, weight/BMI, degree of understanding and cooperation

19
Q

Clinical effects of IV midaz

A
Anxiolytic - relieve anxiety 
Hypnotic 
Sedation 
Amnesia 
Anti-convulsant 
Decrease in skeletal muscle tone
20
Q

Contraindications to IV sedation

A
Allergy to benzos 
Pregnancy at any stage 
Age
ASA III, IV, V
Poor veins
High or very low BMI
Those with respiratory depression
Those with complex lung conditions that cause acute pulmonary insufficiency 
Those with severe hepatic impairment 
Those with sleep apnoea - not suitable as outpatient
21
Q

Midazolam contraindications

A

Hypersensitivity to benzos
Myaesthenia gravis - chronic autoimmune disorder causing weakness in skeletal muscles
Shock or vital sign depression
Acute narrow angle glaucoma - potential to cause blindness due to high pressure in eye damaging optic nerve

Be careful when pt on other form of benzo, takes social drugs (e.g. cannabis), alcohol abuse, other sedatives

22
Q

Flumazenil

A
Reverses effects of benzos 
200mcg every 1-2 mins as required 
Onset 1-2 mins, peak 6-10 mins
Competitive inhibitor of benzos 
Elimination half life = 53 mins
Potential for resedation due to shorter half life of F to M
23
Q

Venepuncture

A

IV access with cannula
IA - accidental. If pre-drug, remove cannula and apply pressure for extended period. If post-drug, contact local vascular surgeons - medical emergency

Transfixation - cannula passes through vein
Haematoma - bleeding into tissue due to lack of pressure or leakage from vessel
Embolism - foreign body

24
Q

Pharmacokinetics / pharmacodynamics of NO2

A

Pharmacokinetics:
Inhaled into lungs through nasal mask
Travels down partial pressure gradients - though lungs - alveolus - bloodstream/capillaries
Hardly metabolised - excreted through lungs
Elimination half life - 5 mins

Pharmacodynamics:
Analgesic 
Anaesthetic - still need LA
Hypnotic 
Anxiolytic - acts on GABA
25
Q

Stages of anaesthesia:

A
  1. Analgesia - most dental procedures within this
  2. Excitement
  3. Surgical analgesia
  4. Respiratory paralysis
26
Q

Signs of oversedation - IHS:

A
Hysterical laughter, tears 
No longer enjoying effects 
Decreased cooperation 
Nausea/vomiting 
Mouth closing repeatedly
Snoring
Incoherent speech 
Irrational and sluggish responses
Loss of conciousness ultimately
27
Q

Contraindications IHS:
Social
Medical
Dental

A
Social:
Claustrophobia 
No consent 
No escort 
Severe anxiety 
Lack of understanding of treatment 

Medical:
Blocked nose/URTI/unable to breathe through nose
Myasthenia gravis
Pregnancy
Bleomycin therapy
Recent surgery eye/middle ear/intracranial/sinus

Dental:
Traumatic procedures
Txt of upper anterior teeth

28
Q

Safety features IHS

A

Pin index - tube only fits to specific gas so cant give wrong one
Scavenging at 40L/min - legal requirement. Important so dental team dont inhale gas. Removes any gas exhaled by pt - check within 2 blue lines
Nasal mask and tubing - check no holes
Oxygen failsafe - if O2 stops, nitrous oxide will stop too to prevent giving 100% nitrous
Mayx 70% N2O - unable to give more
Oxygen flush - delivers high rate oxygen through mask in oversedation emergency
Air entrapment valve - ensure clear and no obstruction of holes
Reservoir bag - monitor how well pt breathing, check expiry

29
Q

IHS pre-op instructions

A

Light meal
Take routine medications as normal
Children must be accomapanied by competent adult
No other kids
Can cause dizziness/headache.nausea at higher doses

30
Q

IHS - technique:

A

Safety checks, consent, escort
Introduce to child - let them feel mask, giggle gas, what they will feel/experience, nice sensation
Start oxygen and turn up flow rate 5-6L/min
Fit mask and encourage nose breathing - let pt put mask on nose, tighten, practice nose breathing with 100% O2
Titrate N2O at 10% per min to 30% then 5% per min until adequate sedation
Hypnotic suggestion, clinical monitoring
100% O2 min. 3 mins to recover

31
Q

Advantages IHS

A

Non-invasive
Drug easily altered/discontinued
Minimal impairment reflexes
Drug administered and excreted via lungs - no metabolism so rapid recovery
No fasting required
No escort for adults
Some analgesia - 50%N2O equiv to 10mg morphine

32
Q

Disadvantages IHS

A

Lack of potency of nitrous oxide - not as good as IV sed with midaz
Expensive equipment - maintenance exp
Space occupying equipment
Patient perception of equipment
Difficulty treating upper anterior teeth
Lack of control of pt cooperation - if pt doesn’t breathe through nose, wont work
Requirement of clear nasal airway
Chronic exposure of staff
Potential for staff addiction

33
Q

Contraindications to IHS

A

Respiratory tract infection
Nasal obstruction
Severe personality disorders
Pt’s taking methotrexate - can increase toxicity
Myaesthenia gravis
MS
Pt’s with claustrophobia
Treatment that will be obstructed by mask
Psychiatric disorders
Pregnancy - esp 1st trimester
Recent ophthalmic surgery using intraocular gases
Cyanosis at rest due to chronic cardiac or resp disease
Severe chronic pulmonary condition

34
Q

Process for hypnosis

A

Preperation - prepare pt to feel good about whats coming
Induction - intro to process
Deepening - increase physical relaxation and intensity of image to help pt disassociate
Specific suggestions/imagery
Post-hypnotic suggestions
Alerting - confirm pt is fully back to their senses