Pain

Question 1

What Detects Pain?

Answer 1

Nociceptors

Question 2

What is pain

Answer 2

An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage

Question 3

First Pain

Answer 3

First pain: sharp Aδ fibers

Question 4

Second pain

Answer 4

: delayed, diffuse, and longer-lasting C fibers

Question 5

dorsolateral tract of Lissauer

Answer 5

cross the midline
and then ascend towards the brainstem
and thalamus

Question 5

Lateral spinothalamic tract-

Answer 5

this carries most of the pain
and temperature
information

Question 5

Anterior spinothalamic tract

Answer 5

carries some crude touch
information

Question 5

Anterolateral crossing

Answer 5

axons cross the
midline when they are leaving the
spinal cord

Question 6

Dorsal column-medial lemniscus crossings

Answer 6

medulla

Question 7

Dorsal column-medial lemniscus:

Answer 7

general somatosensory
information

Question 8

First pain in the brain

Answer 8

ventral posterior lateral (VPL) nucleus-> Pain information relayed to primary and secondary somatosensory cortices

Question 9

Second pain: affective-motivational in the brain

Answer 9

Reticular formation: alerting and
threat area
* Periaqueductal gray: contains
enkephalin-producing cells which can
help suppress pain
* Superior Colliculus: avoidance and
defensive behaviors

Question 10

hyperalgesia

Answer 10

Sensitization

Question 11

peripheral sensitization

Answer 11

inflammatory soup, Probably to help you protect the damaged area until it is healed

Question 12

central sensitization

Answer 12

Increased excitability of neurons in the dorsal horn after a period of high
pain transmission