Pain Flashcards
What is neuropathic pain?
Pain caused by a lesion or disease affecting somatosensory system and may lead to loss of function, increased pain sensitivity, and spontaneous pain.
What is breakthrough pain?
Transient exacerbation of pain, occurs spontaneously in relation to a specific trigger despite relatively stable background pain which is adequately controlled.
How long does breakthrough pain usually last?
Mean duration of 30 minutes.
How is pain assessed?
- Impact on quality of life
- Psychological wellbeing
- Sleep quality
- General function
What are the steps on the WHO pain relief ladder?
- Non-opioid +/- adjuvant
- Opioid for mild/moderate pain +/- non-opioid +/- adjuvant
- Opioid for moderate/severe pain (stop previous opioids) +/- non-opioid +/- adjuvant
What should be prescribed alongside strong opioids?
Regular laxatives and PRN anti-emetics
What are the options for adjuvant pain relief?
NSAIDs, amitriptyline, pregabalin, steroids, bisphosphonates, TENS, radiotherapy.
What is the first line strong opioid for those with normal renal function?
Morphine sulphate
What are the two options for prescribing morphine sulphate?
- Immediate release - Oramorph (10mg/5ml) or Sevredol tablets - lasts 4 hours
- Modified release capsules (Zomorph) or tablets (MST) - lasts 12 hours so give BD
What are the conversion factor for doses of oral morphine to these opioids?
- SC morphine
- Oral oxycodone
- SC diamorphine
- Oral codeine
- Divide by 2
- Divide by 2
- Divide by 3
- Times by 10
What is the conversion factor for oral oxycodone to SC oxycodone?
Divide by 2
What are the second and third line options if a patient is not tolerating morphine sulphate?
2nd line - Oxycodone
3rd line - syringe Alfentanil
What other pain relief should you prescribe as well as regular analgesia and why?
PRN opioid for breakthrough pain
How is the dose of breakthrough opioid pain relief calculated?
1/6th of the total 24 hour opioid dose
How many PRN opioid doses should make you consider changing the background pain relief doses?
> 3