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prudent ab! > page 3 > Flashcards

page 3 Flashcards

1
Q

peptide antibiotcs

A

polypeptide ab

glycopeptide ab

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2
Q

Polypeptide antiobiotcs

A

bacitracin
polymyxin B
polymyxin E (colistin)

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3
Q

polypeptide ab mode & mechanism of action

A

concentration-dependent bactericidal

acts like a cationic-detergent

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4
Q

Glycopeptide ab

A

vancomycin
teicoplanin

(tico is planin to by a van)

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5
Q

glycopeptide ab:

mode, mechanism

A

time dependent bactericidal

inhibition of cell wall synthesis

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6
Q

Rifamycines

A

rifampicin

time-dependent bacteridical
inhibits bacterial DNA-dependent RNA-polymerase

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7
Q

Pseudomonic acid

A

mupirocin

? - bactericidal
inhibits cell wall synthesis

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8
Q

Phosphonic acid derivatives

A

fosfomycin

? - bactericidal
inhibits cell wall synthesis

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9
Q

Fusidic acid

A

fusidic acid

bacteriostatic
inhibits protein synthesis

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10
Q

Sulphonamide AB

A

“sulfa-“

sulfadimidine
sulfadiazine
sulfachlorpyridazine
sulfamethoxasole
sulfadoxine
sulfaquinoxaline
sulfasalazine
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11
Q

sulphonamide: mode, mechansim

A

sep. bacteriostatic
combo. time-dependent bactericidal

inhibits folic acid synthesis

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12
Q

Diaminopyrimidines

A

“-prim”
trimethoprim
baquiloprim

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13
Q

diaminopyrimidine: mode, mechanism

A

sep. bacteriostatic
combo. time-dependent bactericidal

inhibits folic acid synthesis

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14
Q

Fluroquinolones 1st gen

A

nalidixic acid*

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15
Q

Fluroquinolones 2nd gen

A

flumequine*

norfloxacin
orbifloxacin
ciprofloxacin
enrofloxacin
danofloxacin
difloxacin
marbofloxacin
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16
Q

Fluroquinolones 3rd gen

A

levofloxacin
sparfloxacin

(3 floor levels in spar)

17
Q

Fluroquinolones 4th gen

A

pradofloxacin
moxifloxacin

(4 pride and moxi)

18
Q

fluroquinolones: mode, mechanism

A

concentration-dependent bactericidal
inhibits dna synthesis

“-floxacin, nalidixic acid, flumequine”

19
Q

Nitrofurans

A

nitrofurantoin

furzazolidone

20
Q

nitrofuran: mode, mechanism

A

? - bactericidal

destroy DNA

21
Q

Nitroimidazoles

A

“-dazole”

metronidazole
ronidazole
tinidazole

22
Q

nitroimidazole: mode, mechanism

A

concentration-dependent bactericidal

destroy DNA

prudent ab! (4 decks)

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