page 3 Flashcards
peptide antibiotcs
polypeptide ab
glycopeptide ab
Polypeptide antiobiotcs
bacitracin
polymyxin B
polymyxin E (colistin)
polypeptide ab mode & mechanism of action
concentration-dependent bactericidal
acts like a cationic-detergent
Glycopeptide ab
vancomycin
teicoplanin
(tico is planin to by a van)
glycopeptide ab:
mode, mechanism
time dependent bactericidal
inhibition of cell wall synthesis
Rifamycines
rifampicin
time-dependent bacteridical
inhibits bacterial DNA-dependent RNA-polymerase
Pseudomonic acid
mupirocin
? - bactericidal
inhibits cell wall synthesis
Phosphonic acid derivatives
fosfomycin
? - bactericidal
inhibits cell wall synthesis
Fusidic acid
fusidic acid
bacteriostatic
inhibits protein synthesis
Sulphonamide AB
“sulfa-“
sulfadimidine sulfadiazine sulfachlorpyridazine sulfamethoxasole sulfadoxine sulfaquinoxaline sulfasalazine
sulphonamide: mode, mechansim
sep. bacteriostatic
combo. time-dependent bactericidal
inhibits folic acid synthesis
Diaminopyrimidines
“-prim”
trimethoprim
baquiloprim
diaminopyrimidine: mode, mechanism
sep. bacteriostatic
combo. time-dependent bactericidal
inhibits folic acid synthesis
Fluroquinolones 1st gen
nalidixic acid*
Fluroquinolones 2nd gen
flumequine*
norfloxacin orbifloxacin ciprofloxacin enrofloxacin danofloxacin difloxacin marbofloxacin