Page 210 Flashcards
Epoetin alfa (erythropoietin)
Clinical uses
Anemias (especially in renal failure)
Thrombopoietin
Clinical uses
Thrombocytopenia
Oprelvekin (interleukin-11)
Clinical uses
Thrombocytopenia
Filgrastim (granulocyte colony-stimulating factor)
Clinical uses
Recovery of bone marrow
Sargramostim (granulocyte-macrophage colony-stimulating factor)
Clinical uses
Recovery of bone marrow
Aldesleukin (interleukin-2)
Clinical uses
Renal cell carcinoma, metastatic melanoma
IFN-α
Clinical uses
Chronic hepatitis B and C, Kaposi sarcoma, hairy cell leukemia, condyloma acuminatum, renal cell carcinoma, malignant melanoma
IFN-β
Clinical uses
Multiple sclerosis
IFN-γ
Clinical uses
Chronic granulomatous disease
Alemtuzumab
Target/clinical use
CD52
CLL
“Alymtuzumab”—chronic lymphocytic leukemia
Bevacizumab
Target/clinical use
VEGF
Colorectal cancer, renal cell carcinoma
Cetuximab EGFR
Target/clinical use
Stage IV colorectal cancer, head and neck cancer
Rituximab
Target/clinical use
CD20
B-cell non-Hodgkin lymphoma, rheumatoid arthritis (with MTX), ITP
Trastuzumab
Target/clinical use
HER2/neu
Breast cancer, gastric cancer
HER2—“tras2zumab”
Infliximab, adalimumab
Target/clinical use
TNF-α
IBD, rheumatoid arthritis, ankylosing spondylitis, psoriasis
Rheumatoid arthritis “inflix” pain in “da limbs”