Page 1 of objectives Flashcards
Basics of hormonal regulation of menstrual cycle
- LH
- FSH
- Estrogen
- Progesterone
- LH is released from pituitary
- Surges at ovulation
- Leads to release of oocyte
Basics of hormonal regulation of menstrual cycle
- LH
- FSH
- Estrogen
- Progesterone
- FSH is released from the pituitary
- Surges at ovulation
Basics of hormonal regulation of menstrual cycle
- LH
- FSH
- Estrogen
- Progesterone
- Estrogen is released from the ovary
- Rises during follicular phase; peaks right before ovulation
- Causes thickening of endometrium of uterus
Basics of hormonal regulation of menstrual cycle
- LH
- FSH
- Estrogen
- Progesterone
- Progesterone is released from the granulosa cells of the corpus luteum that contained the oocyte
- At its lowest at ovulation; rises and peaks during luteal phase, prepping for a fertilization
- If no fertilization, levels fall and endometrial lining is shed, 14 days after ovulation
General maternal physiologic changes in pregnancy:
Hematalogic
- Hematocrit will drop due to dilution
- Also, pregnancy is a hypercoagulable state
General maternal physiologic changes in pregnancy:
Cardiovascular
- Cardiac output rises 30-50%
- Maternal heart rate rises by 15 to 20 beats/min
- Systolic and diastolic blood BP typically fall early in gestation and are about 5 to 10 mmHg below baseline in the second trimester. In the third trimester, blood pressure gradually increases and may normalize to nonpregnant values by term.
General maternal physiologic changes in pregnancy:
Respiratory
- Chronic respiratory alkalosis
- May get unilateral nasal polyp, called nasal granuloma gravidarum
How is pregnancy diagnosed?
The diagnosis of pregnancy is based on the presence of any of the following:
●Detection of human chorionic gonadotropin (hCG) in blood or urine
●Identification of pregnancy by ultrasound examination
●Identification of fetal cardiac activity by Doppler ultrasound
GTPAL system
G = number of pregnancies; twins counts as one pregnancy
T = number of term births (has reached at least 38 weeks; each twin counts as a birth)
P = number of preterm births (20 weeks to 37 weeks)
A = number of abortions/miscarriages (less than 20 weeks)
L = number of living children
Calculate estimated date of delivery (EDD) based on LMP
- EDD is 280 days from the onset of the last menstrual period (LMP) and 266 days from date of conception
- Naegele’s rule: Subtract 3 months, add 7 days to first day of LMP
What is the role of folic acid in fetal development?
What is the current recommendation regarding folic acid supplementation?
- Folic acid supplementation decreases the occurrence of neural tube defects (e.g. spina bifida, anencephaly) and is recommended for women planning pregnancy or capable of becoming pregnant
- Recommendation is supplement containing 0.4 mg to 0.8 mg of folic acid daily
What is Chadwick’s sign?
Bluish discoloration of the cervix from venous congestion, usually visible by 8-10 weeks.
What is the recommended frequency of prenatal visits?
- Every 4 weeks until 28 weeks
- Every 2 weeks from 28-36 weeks
- Every week from 36 weeks-delivery
What is the recommended weight gain during pregnancy?
Depending on weight prior to pregnancy…
…underweight (BMI < 18.5): 28-40 lbs
…normal weight (BMI 18.5-24.9): 25-35 lbs
…overweight (BMI 25-29.9): 15-25 lbs
…obese (BMI 30+): 11-20 lbs
(ACOG)
What are the screening tests (mother and fetal) of the first trimester?
- First trimester screen: u/s for fetal nuchal translucency, plus hCG and PAPP-A
- 10-14 weeks
- Asymptomatic bacteriuria
- 12-16 weeks