Paeds Flashcards
What symptoms are associated with HSP?
Purpuric rash, joint pain, abdo pain
What is the likely Hx in HSP?
Recent throat infection
What investigation is key in HSP follow up and what are you looking for?
Urine - proteinuria and haematuria
Where is the rash most commonly seen in HSP?
Legs and bum, arms face and trunk
Diagnosis of HSP?
Bloods - raised IgA, CRP, ESR, platelets
What distinguishes HSP from ITP/TTP?
Low platelet count
what are the cyanotic CHD?
- VSD
- ASD
- PDA
What are the symptoms of VSD?
Tachycardia, tachypnoea, panysystolic murmur at lower left sternal edge
What are the symptoms of ASD?
Asymptomatic!!! Ejection systolic murmur at left upper sternal edge
What are the symptoms of PDA?
Continuous blowing murmur below left clavicle
What time frame is a PDA pathological?
> 1 month
How do you treat a small VSD?
Leave it and it will spontaneously close but monitor
How do you treat a PDA?
NSAIDS to close it
What are the cyanotic CHD?
Tetralogy of Fallot and transposition of great arteries
What are the 4 features of ToF?
- Pulmonary stenosis
- Overriding aorta
- VSD
- Right ventricular hypertrophy
What are the symptoms of ToF?
Cyanosis, difficult breathing, squatting on exercise, clubbing of fingers and toes and systolic murmur
How is ToF treated?
Open heart surgery
Beta blockers
noradrenaline
What vessels are affected in transposition of great arteries?
SVC, IVC, Pulmonary artery, pulmonary veins, aorta
When is Transposition identified?
When the ductus arteriosis closes
How do you treat Transposition (2 things)
Induce a PDA with prostaglandins and arterial switch operation
What is the leading cause of acute epiglottis?
H. influenza B
What is a key fact in kids with acute epiglottis
Not up to date with vaccines!!!!
What are some symptoms of acute epiglottits
Sat upright, open mouth breathing, drooling, can’t speak or swallow, NO COUGH
What is the most important thing to do when you suspect acute epiglottis?
Call anaesthetist to intubate
What must you NOT do in acute epiglottis?
Examine throat
What symptoms are suggestive of croup?
Worse at night, barking cough, stridor, following short coryzal episode
What is the most common cause of croup?
Parainfluenza
What heart murmur would you get for pulmonary stenosis?
Ejection systolic at left upper sternal edge
What heart murmur would you get for aortic stenosis?
Ejection systolic at right upper sternal edge
What heart murmur would you get for coarctation of the aorta?
ejection systolic at left upper sternal edge
What symptoms might you get for coarctation of aorta?
Increasing with age, SoB, intermittent claudication, radio-radial/femoral delay
What are the 4 S’s of harmless murmurs?
- Soft
- Systolic
- aSymptomatic
- left Sternal edge
Investigations if you find a murmur?
ECHO (antenatal)
ECG
CXR
What direction does the blood flow in Acyanotic CHD?
Left to right
What direction does blood flow in cyanotic CHD?
Right to left
What syndrome do you get if you do not treat acyanotic heart defects?
Eisenmenger’s syndrome
What is the risk with Eisenmenger’s?
Reversal of L-R shunt so causes cyanosis
What is the other name for croup?
Laryngeotracheobronchitis
Where in the resp tract is the obstruction in croup?
Upper
Age range for croup?
6 months - 6 years (peak at 2y)
Tx for simple croup?
Dexamethasone (single dose - 0.15mg/kg)
OR
Nebulised budenoside
Tx for severe croup?
High flow oxygen
Nebulised adrenaline
Tx for acute epiglottis?
IV Cefuroxime
What is the other name for whooping cough?
Pertussis
What is the main cause of whooping cough
Bordatella pertussis
What are the symptoms of whooping cough?
Inspiritory whoop, worse at night, vomiting, cyanosis, nose bleeds, subconjunctival haemorrhages
How long does phases of whooping cough last?
Paroxysmal phase = 3-6 weeks
Cough = months (100 days_
Ix for whooping cough?
Nasal swab culture and PCR
Tx for whooping cough if <1 month old?
5 days of Azithromycin
Tx for whooping cough in >1 months old?
7 days of Azithromycin and Erythromycin
What is the main age range for bronchiolitis?
1-9 months
What is the main cause of bronchiolitis?
RSV (respiratory syncytial virus)
What are some other causes of bronchiolitis?
Parainfluenza, human metapneumovirus
Symptoms of bronchiolitis?
Resp distress, coryzal, breathless, poor feeding
6 signs of resp distress?
Head bobbing, nasal flaring, subcostal recessions, intercostal recessions, tracheal tug, grunting
Ix for bronchiolitis?
Nasal swab and PCR
CXR for hyperinflation
Mx for bronchiolitis?
SUPPORTIVE!!!
humidified O2
NG feeds if cannot feed
Fluids
What is a preventative treatment for bronchiolitis, and when is it given?
Palivizumab.
IM once a month
Indications: CF, downs, immunocompromised, CHD
Define asthma
Chronic inflammatory disorder of the lower airways, secondary to hypersensitivity. It is reversible airway obstruction.
Classic triad of symptoms in asthma?
- Bronchospasm
- Mucosal swelling and inflammation
- increased mucus forming a plug
Features of asthma
Nocturnal dyspnoea, wheeze, cough, sputum, diurnal variation, low exercise tolerance, disturbed sleep
Diagnosis of asthma (3 kinds)
- FEV1:FVC = <70%
- Reversibility with bronchodilator of FEV +12%
- FeNO >35ppb
What cells are involved in asthma?
CD4 cells / eosinophils / IgE
What role does IgE have in asthma?
Binds to mast cells in mucosa, causing release of inflammatory mediators + histamine
What causes increased mucus in asthma?
Histamine
What Tx must be done for asthma in all ages?
Avoid triggers, check inhaler technique
What to add if SABA and low dose ICS don’t work in >5y?
Leukotriene receptor antagonists (e.g. Montelukast)
If SABA, ICS, LTRA don’t work in asthma >5y
LABA / Maintenance and reliever therapy
What to add if asthma not controlled by SABA in <5y?
8 week trial of moderate-dose ICS
Difference in measuring <5 and >5y asthma attack
If >5y must include PEF values
Severe asthma attack
- Sats <92%
- PEF <50%
- Unable to talk
- Tachycardic and pnoeic
- Use of accessory muscles
Life threatening asthma attack
- Sats <92%
- PEF <33%
- Silent chest
- Poor resp effort
- Decreasing consciousness
- Cyanosed
Mx of asthma attack
- ABCDE
- High flow O2
- Nebulised Salbutamol
- IV Hydrocortisone
- Ipratropium Bromide
- Mg Sulphate IV
CALL ICU!!!!!!!!!
Mx CF
High calcium and fat diet
Chest physio and draining
Pancreatic enzyme replacement therapy
Prophylactic Abx
Main pathogens in causing chest infection in CF
Pseudomonas aeriginosa
Staph aureus
What acid-base disturbance might you find in pyloric stenosis
HypoK, hypoCl, metabolic acidic alkalosis
Most common site for intussusception?
Ileum into caecum via oleo-caecal valve
What signs would you find in intusseption?
Child drawing knees up to chest and going pale.
Redcurrent jelly stool.
Sausage shaped mass in Right Lower Quadrant
What would an USS show if a pt had intussusception?
Doughnut / target sign
How to treat intussusception?
Rectal air insufflation
What can intestinal malrotation lead to?
Volvulus and infarction of the entire midgut
What age does intestinal malrotation present?
1-7 days
Signs and symptoms of intestinal malrotation
BILLIOUS VOMITING
Abdominal pain
Tenderness
What is the single diagnostic test for malrotation?
Upper GI contract study
What is the treatment for intestinal malrotation?
Ladd’s procedure - rotate bowel anticlockwise
What would you suspect in a premature baby that is fed with cow’s milk with GI symptoms?
Necrotising enterocolitis