Important ILA Points Flashcards
What makes up a septic screen?
- Urinalysis
- Bloods (FBC, CRP, U&E)
- Blood cultures
- Lumbar puncture
What is the definition of sepsis?
Inappropriate systemic response to infection that leads to end organ dysfunction
What are serious bacterial infections in kids?
- UTI
- Meningitis
- Pneumonia
- Bacteraemia
What would results of CSF be in meningococcal septicaemia?
- High neutrophil count
- No red cells
- Low glucose
- High protein
Why may a child with meningococcal septicaemia present in acidosis?
They are tachypnoeic
Why might you restrict fluids in a child with meningitis?
If they have raised ICP
What would you do if you had given a child with meningitis two boluses and they were still not getting any better
IV inotropes
Call PICU
What antibiotic treatment would you give a 1 year old child with meningitis?
IV Ceftriaxone
IV Amoxicillin
What causes purpura in meningitis?
N. meningitidis releases endotoxins which active factor VII, causing DIC
Would you fluid restrict a child that presented with meningitis?
NO
What antibiotics would you give close contacts?
Rifampicin
What treatment do you start kids on if they have JIA?
NSAIDS
What do you give in JIA if the child still has symptoms after first line treatment?
Steroid injections
Immunosuppressants - methotrexate / etanercept
What is the criteria for Kawasaki’s?
BURN (>38 for 5 days) Conjuntivitis Rash - trunk and extremities Adenopathy - cervical Strawberry tongue Hands - oedema erythema
When do you reduce the dose of aspirin in Kawasaki?
When the fever is gone
What two drug treatments do you give in Kawasaki’s?
- Aspirin
2. Gamma globulin (STAT)
What investigation is key in Kawasaki’s?
ECHO - initial and 6 week
What syndrome can aspirin cause?
Reye’s - liver and brain damange
What happens cardio wise in Kawasaki?
Inflammation of vessels which leads to formation of aneurysms. May heal but may thrombus and cause MI
What would a blood gas show in DKA?
Metabolic acidosis
What tests do new diabetics need to have (3)?
- Thyroid
- Coeliac
- Haemoglobin
Why do you fluid restrict in DKA?
Cerebral oedema
When do you start giving insulin in DKA?
1 or 2 hours after fluid replacement starts
What does do you give of insulin in DKA?
0.1 units/kg/hour CONTINUOUSLY
What do you add in after insulin starts to work
5% Dextrose (when glucose <14)
Leading cause of congenital hypothyroid in UK?
Dysgenesis/aplasia of thyroid gland
Leading cause of congenital hypothyroid worldwide?
Iodine deficiency
What medication do you give for hypothyroid (congenital) and how does dose matter?
Levothyroxine
- Start 10-15 mg/kg
- Increase by 5 very fortnight
- Maintain on 20-50 mg/kg
What would untreated congenital hypothyroidism lead to?
Cretinism
What are some symptoms you may notice if congenital hypothyroidism went undiagnosed?
Learning disability
Clumsiness
Short
Large tongue
What are some causes of critically unwell neonates?
Trauma NAI Heart disease Endocrine - CAH Metabolic - hypo's Inborn errors of metabolism Sepsis Formula issues Intestinal problems Toxins Seizures
What blood gas results might you see in congenital adrenal hyperplasia
Metabolic acidosis with partial respiratory compensation, with hyponatraemia and hyperkalaemia
If a neonate presents with CAH in <24h, how might they present?
Salt losing crisis
How would you treat a baby <24h in CAH?
NaCl, dextrose, hydrocortisone
How might a girl present with CAH?
Ambiguous genitalia
hypertrophic clitoris, fused labia