Paeds Flashcards

1
Q

Differentials for abdo pain according to age

A
  • Everyone gets infections
  • Neonates get congenital things
  • Older kids get DKA and adulty things
  • Don’t forget constipation
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2
Q

A 5 year old with frequent exacerbations of asthma comes in to the ED unable to speak from breathlessness. How would you manage this patient in the acute and long term setting? How would you explain to the parents what “asthma” is, and the side effects of common medications?

A
  • kids w SOB: asthma, anaphylaxis, FOREIGN BODY, infection
  • look for silent chest
  • give fluids, remembering that oral > NG > IV
  • Mx: nebulised SABA and oral pred (if tolerated)
  • Add ipratropium if moderate/severe
  • Try Mag sulfate, IV SABA if reeaaall serious; have to give steroids IV
  • long term management
  • side effects: beta agonist (irritability, tachy, palpitations), steroids (growth, healing, obesity, DM, thin skin, increased infections, depression,
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3
Q

A 2 year old girl with inspiratory stridor and barking cough presents breathless to ED. How would you assess the severity and manage this patient? If this is the patient’s 3rd episode of stridor this week, what condition could this be and how can you assess this further?

A

PDx: croup (unusual less than 6 months old)
DDx: bacterial croup, epiglottitis, asthma, anaphylaxis, foreign body

1) Primary survey
- assess severity of group: behaviour, stridor, RR, accessory muscles, O2
- give steroids, and then nebulised adrenaline if real serious; PICU if no improvement
- avoid unnecessary distressing things (eg O2, o/e) because distress will worsen airway obstruction

2) History and exam
(investigations unnecessary unless differentials not excluded)

3) Discharge criteria: child feeling better, no stridor at rest four hours after nebs

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4
Q

A 7 year old girl with a history of peanut allergy presents to the ED after having collapsed. She had eaten an ice cream which may have contained nuts. How would you manage this child?

A
  1. anaphylaxis = hypotension +/- upper/lower airway +/- skin +/- GI
  2. give adrenaline (1:1000) every 5 min: 0.15mL upto 6 years; 0.3mL from 6-12yo; 0.5mL over 12yo
    infusion if no response and NS for shock
    anti-histamines after stabilisation for pruritis
  3. Watch for at least 4 hours
  4. EDUCATION - anaphylaxis action plan, epipen Jnr (<20kg), medicaid bracelet
  5. paed immunology referral
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5
Q

A 4 year old boy is brought in by his mother for poor appetite and weight loss. He also has a history or persistent low-grade fever and bruising. His examination findings reveal pinpoint macules on the mucosa of his mouth, generalized lymphadenopathy and hepatosplenomegaly. Assess and manage.

A 4 year old girl presents with a 4 week history of bone pain and a limp, with a 2 day history of petechiae, purpura and bruising. On examination, she had hepatosplenomegaly. Her WCC is 211 x 109/L and her platelets are 52 x 109/L. Discuss your differential diagnoses and management.

A

PDx: ALL
DDx: AML, non haem malignancy with bone marrow involvement (neuroblastoma, rhabdo), primary haem condition eg aplastic anaemia, ITP; infection: EBV, CMV

1) History and exam
- don’t forget to check testes
2) Investigations
- don’t forget to do LP (CNS involvement), UEC (tumour lysis)
- consider CXR for mediastinum, testicular U/S if enlarged
3) Management
- chemo involves induction, consolidation, maintenance
+/- INTRATHECAL
- supportive care: nutrition
- social support

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6
Q

A 10 year old boy presents with a 2-day history of fever and acute abdominal pain which later localises to the RIF. How would you assess and manage this child?

A

PDx: appendicitis
DDx: mesenteric adenitis, gastro, IBD, obstruction, malignancy - don’t forget DKA and testicular torsion as abdo pain differentials

1) history and exam: 
incl does it hurt when you cough
2) Ix "aPPenDiCItis iS a CliNicAL diAGnoSIs"
- U/S > CT
3) Management
- supportive care: fluids, analgesia
- peritonitis empirical abx: gent + amp + met
- lap app
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7
Q

A 4 month old with 1st episode wheezing with a temperature of 38 degrees is in ED with breathlessness and taking only 1/3 of feeds. He has no past history of chronic lung disease. What is the acute management for this episode and when will the patient be discharged? How would you advise the parents about this condition?

A

PDx: bronchiolitis
DDx: pneumonia, croup etc

Assess

  • primary survey and resus
  • severity
  • risk factors: young, prem, CF, CHD, smoking exposure
  • sx of other respiratory tract symptoms
  • investigations only if unclear diagnosis

Mx

  • supportive: O2 if necessary, rehydration (PO > NG > IV)
  • transfer to tertiary centre if severe
  • parent education and counselling
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8
Q

A 3 year old boy presents with three rashes. How would you manage each of these?
A. Crusting weeping lesions
B. Lazy erythematous rash on check
C. Dry scaly itchy skin lesions on flexors with signs of cracking.

A

General principles

  • check vitals for toxicity, do systems exam for location
  • consider fluid MCS

A. impetigo:

  • look for primary skin injury
  • Mx: saline baths, isolation and abx - in non-remote areas give mupiricin topical or fluclox PO if widespread/recurrent

B. slapped cheek:

  • check for aplastic crisis in Hbpathy kids
  • Mx: symptomatic (analgesia, topical antihistamines), avoid sun

C. atopic dermatitis:

  • ask about atopy
  • Mx: avoid irritants, moisturiser and wet dressings, dilute bleach baths, topical steroids
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9
Q

V1. A 2 month old presents with an audible murmur. She gets breathless and sweaty with feeds and takes a long time feeding. There is a history of poor weight gain. Discuss your management including long term prognosis and possible complications.

V2. A 1 month old baby brought in by mum complaining of very poor feeding, sweating during feeds and breathless. On examination, the baby has a loud systolic murmur, is tachycardic and has an enlarged liver. How do you assess and manage?

A
  • with murmurs it’s usually nothing, but if it is it’s probably VSD
  • if it’s soft and systolic, be a bit reassured
  • if they’re symptomatic, be suspicious
  • look for the signs - ‘holosystolic murmur at lower left parasternal edge’
  • check for FTT
  • small VSD heals by itself, but give abx to prevent IE

PDx: congenital heart disease (VSD)
DDx: innocent murmur

Assessment

  • hx of CHD symptoms: colour, heart failure sx, resp sx, FTT
  • CHD risk factors: caught on U/S, perinatal insults, Down’s, FHx
  • rest of history
  • examine for murmur and heart failure, growth
  • ECG, consider CXR, echo

Management: depends on lesion and size (?persisting at 2 months with FTT means likely surgery)

  • small: wait for it to close, give abx (amoxycillin to prevent IT
  • large: frusemide to treat pulm oedema, surgery, postop abx
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10
Q

7 year old girl presents with her mother, complaining of constipation. All examination and investigation findings are normal. Discuss management.

A

DDx

  • usually functional with behavioural component
  • could be meds
  • most organic causes (neuro, metabolic, GI anatomy, coeliac) will usually present much younger eg infancy

Assessment

  • Bristol Stool Chart
  • reassuring: incontinence, withholding behaviour
  • growth n dev, abdo, DRE, lower limb neuro
  • RED FLAGS: fever, bleeding, severe distension, FTT, neuro sx
  • NO AXR other other ix except as per suspicion on hx

Management
- start with conservative mx (incl a diary)
- consider toilet retraining: unhrried, correct position, encourage 2-3/day regardless of need
. then start an osmotic/lubricant laxative if conservative mx not working, to get porridgey stools

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11
Q

During the newborn examination, a 2-day old neonate was found to have a right dislocatable hip. Discuss your management.

A

PDx: DDH

Assessment

  • History of risk factors (things which mean the hips are squished - oligohydramnios, breech), leg problems
  • Barlow is first (B before O), Bringing the knees together, then Ortolani is next, taking the knees Out
  • Then imaging: U/S if less than 6 months, xray if more than 6 months

Management:

  • Pavlik harness 24/7 for 6 weeks and then only at night if under 10 months old (check position with U/S after 2-3 weeks, stop after clinically stable hip and U/S shows acetabulum)
  • Closed/open reduction and spica cast for 6-9 weeks if older
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12
Q

6 year old boy with vomiting and worsening abdominal pain, tachycardic, tachypnoeic and hypotensive. Patient is in shock. Assess and Manage.

A child presents to the ED with diabetic ketoacidosis. Discuss your management of this child.

A 6 year old boy with vomiting and worsening abdominal pain is brought to the ED by his mother. He is tachycardic, tachypnoeic and hypotensive. How would you assess and manage this child?

A

PDx: DKA
DDx: infective gastroenteritis, bowel obstruction and perforation

1) Primary survey and resus
C: DKA Mx
- Insulin
- K if normal/low
- Watch glucose carefully, give glucose after corrected
- Give fluid very carefully - could lead to cerebral oedema
- DO AN ECG IN CASE OF HYPERKAL

2) Detailed history and exam after stable
- confirm DKA
- look for precipitating cause

3) Continuing management
- supportive: fluids, electrolytes, consider NG if continuing to vomit
- definitive: insulin
- monitoring and consider transferral to tertiary centre: (brain sequelae - comatose, seizures, signs of cerebral oedema)

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13
Q

Liam is a 2 year old boy who is receiving treatment for acute lymphocytic leukaemia. 13 days after his last chemotherapy treatment he develops a fever. Discuss your approach to management.

A

Febrile neutropaenia until proved otherwise:

  • resus
  • IV tazocin
  • thorough look for all possible sites of infection (CV, resp, GI incl mouth, skin, iatrogenic, MENINGITIS)
  • assess for other contributors to infection risk
  • septic screen but NO LP because thrombocytopaenia?
  • fluid resus and abx until negative blood cultures for 48 hours

(??source)

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14
Q

Patrick an 18 month old child is referred to you from his GP because of 2 consecutive days of fevers of 40oC. He has been feeding poorly and tired. He has been otherwise well. He has no vomiting, diarrhoea, cough or runny nose. Discuss your approach to his management and comment on the seriousness of this presentation.

A

DDx:

  • easily missed infections (meningitis, IE, viral)
  • non-infectious (cancer, drug reaction)
Resus if necessary
Assessment
- changes in eat/sleep/pee/poo/play
- systems review
- infection risk factors
- rule out cancer and drug reaction
- septic screen, consider LP

Management
- sepsis empirical abx = CEFOTAXIME (plus amp if <2 months; plus gent and vanc if critically ill)

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15
Q

An 18 month old boy presents with 24 hours of diarrhoea and vomiting. He has reduced feeding to <50% of normal intake and his mother is concerned he is lethargic. How would you manage this child?

A
PDx: viral gastro
DDx: 
acute abdo: appendicitis, intussusception, bowel obstruction, Hirschsprung's
sepsis: UTI, meningitis, pneumonia, AOM
raised ICP if no diarrhoea

Assessment

  • infection hx and exam
  • rule out non-infective gastro - red flags are toxicity, vomiting without diarrhoea, bilious vomiting, PR bleeding, diarrhoea for more than 10 days, abdo pain

Management

  • fluids + electrolytes: PO/NG/IV
  • monitor: EUC and BSL every 6-8 hours if moderate to severe
  • start feeding in 24 hours as vomiting settles
  • discharge home: if dx of infective gastro, child rehydrated and minimal ongoing losses (urinated in past 4 hours), trust parents
  • education
  • F/U with GP in 48 hours
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16
Q

A 3 year old boy presents with bouts of coughing ending with a vomit, these are worse at night and after feeding. Discuss your provisional diagnosis and management.

A

PDx: pertussis
DDx:
viral URTI
atypical pneumonia

Assessment

  • check for toxicity
  • vaccinated children can get less severe disease
  • diagnosis is NPA/swab PCR

Management

  • PICU if serious (apnoea, cyanosis, encephalopathic)
  • otherwise, abx treatment is to minimise transmission ie only give in first three weeks: azithro
  • PREVENT TRANSMISSION - abx prophylaxis for contacts, notify, isolate, vaccinate
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17
Q

A 3 year old boy presents with irritability and found to be tugging his right ear. On examination, discharge was found coming from his right ear. Manage this child.

A

PDx: acute otitis media
DDx: chronic, OME, otitis externa, secondary sepsis/meningitis

Assessment

  • confirm diagnosis
  • CHECK HEARING AND DEVELOPMENT

Management

  • if they’re otherwise fine, (incl socially) give supportive care INCLUDING EDUCATION about re-presenting
  • if they’re systemically unwell/<6 months old/unlikely to represent, consider amoxycillin
  • ENT referral if recurrent or have developed hearing/learning issues

btw, >3 months = chronic

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18
Q

A 2 year old girl comes in with a history of fever to 39oC and later generalized twitching for 5 mins followed by post ictal drowsiness. Her parents commenced mouth to mouth resuscitation when she developed transient cyanosis. Now she is running around in the ED. What is your management?

A

PDx: febrile convulsion
DDx: organic seizure - CNS path (infection, stroke, SOL), ADR, metabolic (glucose, electrolytes)

Assessment

  • want to rule out organic causes - CNS infection/tumour/epilepsy/congenital
  • red flags: focal, >10min, recurrence same day, not completely better by 1 hour
  • workup underlying infection (make sure you’re happy that the underlying infection is viral - rule out sepsis or its possibility)

Management

  • PARENTAL EDUCATION - what it is, what to do if it happens again, what it means long term (only slightly above population risk)
  • symptomatic: panadol, tepid sponging
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19
Q

A 3 month old baby is brought in by his parents who are concerned about his vomiting and poor feeding. Discuss assessment and management.

A

PDx: reflux
DDx: bowel obstruction (pyloric stenosis, atresia, Hirschsprung’s), allergy (CMPA, eggs?), infection/raised ICP

Assessment

  • look for red flags: ATLEs, bilious vomiting, haematochezia/haematemesis, abdo pain/distension, toxicity, failure to thrive, diarrhoea, seizures, fever/lethargy/organomegaly

Management

  • education
  • conservative: horizontal feeding, smaller more frequent meals (don’t lie them prone because SIDS)
  • consider mother avoiding diary and eggs; alternative formulas if formula-fed - thickened, hypoallergenic
  • PPI trial
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20
Q

V1. While doing a newborn check, you hear a cardiac murmur. What other relevant examination findings do you want to know and how will you further assess and manage?
V2. You hear a heart murmur on a postnatal baby check. Discuss your assessment and management.

A

PDx: innocent murmur (soft, systolic, L sternal edge, no thrills or systemic symptoms)
DDx: other CHD

Assessment

  • hx of CHD symptoms: inadequate perfusion (incl FTT), resulting heart failure
  • hx of RF: picked up on U/S, perinatal insults, Down’s etc, FHx (including sudden unexplained death)
  • examine growth, heart, ?failure
  • ECG, CXR, echo if suspicious

Management

  • paed cardiologist
  • consider conservative vs surgical repair
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21
Q

A 15 month old girl is brought in by her mother for a fever and refusal to drink. On examination she was found to have vesicles on her posterior oropharynx, hands and feet. How would you assess and manage this child?

A

PDx: hand, foot and mouth
DDx: chicken pox, HSV,

Primary survey if dehydrated

Assessment

  • check for toxicity, dehydration
  • confirm characteristic presentation: low grade fever, yellow/red vesicles (not clear), painful not itchy, not anywhere else (maybe bum), loss of appetite
  • consider swab PCR

Management

  • supportive: fluids (eg NG), electrolytes, analgesia (eg topical local), antipyretics, education (usually resolves in 10 days)
  • isolation
  • safety net
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22
Q

A 5 year old child presents with a purpuric rash distributed mainly on buttocks and extensors of lower limbs and abdominal pain. What is the most likely diagnosis and how would you manage?

A

PDx: henoch schonlein purpura!
DDx: sepsis (eg from meningitis), coagulopathy secondary to ITP or malignancy

Assessment

  • rule out toxicity
  • confirm characteristic presentation: preceding URTI/vax/med/bites, abdo pain (?with nausea and vomiting), non-blanching palpable rash, (?arthralgia, nephrotic/nephritic syndrome)
  • rule out differentials
  • urinalysis, UEC - consider urine ACR, MCS, skin/renal biopsy if diagnosis not clear

Management

  • symptomatic: analgesia, pred if severe abdo pain/n+v/scrotal pain/severe oedema
  • IV steroids/immunosuppressants/plasmapheresis /transplant if significant renal disease (as per nephro)
  • safety net: repeat urinalysis regularly over first 6 months
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23
Q

Hypoglycaemia

A

PDx: increased glucose use (insulin OD, increased metabolic rate)
DDx: starvation, inborn errors of metabolism

Presentation: SNS, neuro: lethargy, headache, visual disturbance, slurred speech, dizziness, coma, convulsions

Primary survey and resus

  • DO BSL
  • TAKE CRITICAL SAMPLES (5-10mL blood, first urine)
  • Give glucose - oral if tolerated, otherwise IV - repeat if BSL not coming up
  • Check insulin and ketones
  • Check acid-base, lactate

Assessment

  • History of symptoms - fed or fasted? What foods previously? What associated symptoms?
  • Past history: DM, similar episodes especially perinatally, other conditions, stressors
  • Paeds: HEEL PRICK results
  • FHx: unexplained fetal deaths
  • Examine for weight and height, infection, hepatomegaly/hypotonia, dysmorphic features
  • Investigations: BSL, UEC, LFTs, drug screen, insulin, C-peptide, lactate, others; glucagon stimulation test
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24
Q

Katie and Shane bring their 6 week old baby Mackenzie to ED because Mackenzie cries incessantly. Mackenzie was born by emergency CS because of failure to progress. Mackenzie had Apgar scores of 9 and 9. Katie developed a uterine infection and spent 7 days in hospital. Since coming home Mackenzie has “cried non-stop” but this has increased in the last two weeks. Mackenzie is growing well. He is predominantly breastfed, supplemented by one bottle during the night. Steve has just returned to work as a mechanic in the last fortnight. Katie and Steve are exhausted and distraught and don’t know what to do. Discuss your approach to management?

A

PDx: infantile colic
DDx: infection, reflux, feeding problems (under/overfeeding, CMPA, lactose intolerance)

Assessment

  • Characterise irritability - when, how resolved - what’s a typical day
  • Rule out reflux, feeding issues, infection (incl mother’s GBS status)
  • Thorough history
  • Check growth, NAI
  • Consider septic screen if suspicious

Management: education

  • baby not sick, not in pain: excessively sensitive to stimuli
  • crying not due to physical problem
  • will settle down with time
  • minimise environmental stimulation
  • try soothing: patting, rocking, gentle massage, dummy, swing
  • optimise feeding
  • keep crying diary for further assessment
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25
Q

A 16 year old girl comes into the clinic with enlarged cervical LNs. She has been complaining of feeling tired with a flu-like illness. She has a very sore throat. What is the most likely diagnosis and how would you manage this child?

A
PDx: EBV
DDx: 
- infection: CMV, HIV, viral URTI including influenza, bacterial URTI, toxo
- haem cancer
- inflammatory disease

Assessment
- Characterise symptoms: fatigue, ‘flu-like illness’ - viral prodrome for 3-5 days before sore throat, glands etc
- Infection history (sexual history in HEADSS)
- Rule out differentials: URTI sx, cancer sx, SLE sx
- Thorough paeds history
- Examine growth, ENT, LN, hepatosplenomegaly and jaundice, and then as per history
- Investigations: EBV/CMV serology (positive monospot -
heterophile antibody test), FBC (atypical lymphocytosis), CRP,

Management: supportive

  • analgesia, antipyretics, fluids
  • rest: as per patient’s energy level
  • no contact sports for 4 weeks since onset of symptoms
  • education: careful for upper airway obstruction, splenic rupture, meningitis etc
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26
Q

A previously healthy 9 month old boy presents with a history of paroxysmal screaming, episodic pallor, vomiting and pulling up of knees for 8 hours. His mother is panicked and has brought him to the ED where he has passed red currant jelly stools. How would you assess and manage him? What are the contraindications for barium enema?

A

PDx: intussusception
DDx: other acute abdomen eg appendicitis, infective gastro, Meckel’s diverticulitis

Primary survey and resus if hypovolaemic

Assessment

  • confirm dx and rule out differentials
  • toxicity, degree of unwellness
  • assess hydration and perforation (peritonitis), palpable mass
  • imaging: U/S for target sign, AXR for perforation
  • bloods if unwell

Management

  • air enema if stable
  • surgical air enema fails, if perforation suspected
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27
Q

Kawasaki Disease

A

DDx

  • viral infection (URTI, other with skin manifestations)
  • bacterial eg strep, staph
  • other sepsis

Assessment

  • characteristic presentation: high fever for 4 days or more PLUS rash, peripheral oedema, conjunctivitis, strawberry tongue, cervical LN
  • rule out differentials incl sepsis on investigation AND do echo +/- angiography for coronary artery aneurysms (and again 6-8 weeks later)

Management

  • IVIg + aspirin (repeat IVIg if fever persists/recurs, if fever persists/recurs after that, pred)
  • IV abx until sepsis excluded
  • Supportive care: analgesia, antipyretics
  • Education: usually self-limiting
  • Follow up cardiac imaging
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28
Q

Discuss the differential diagnosis of a boy of 8 years with a limp other than Perthes disease. Assess and manage as Perthe’s Disease. Please also cover the Salter Harris classification and revise greenstick fractures.

A

PDx: transient synovitis
DDx: Perthes disease, septic arthritis, trauma and fracture/soft tissue injury, NAI, cancer if chronic, SUFE in older child, DDH in toddler

Assessment

  • Perthes: pain, limited ROM, trendelenberg limp, shorter true leg length
  • SUFE: activity worsened pain, external rotation
  • Cancer: sx, chronic
  • Trauma: hx of trauma, localised tenderness
  • Assess impact: schooling etc
  • Imaging: xray (see smaller epiphysis, wide joint space, maybe cracking if Perthes; ask for frog leg lateral to see a SUFE)

Management

  • Supportive: pain relief
  • Conservative: non-weightbearing, physiotherapy, splints to keep head in acetabulum
  • Surgical (if older, poor prognosis): femoral head osteotomy and bone graft

Salter Harris: straight across, above, beLow, through, erased (crush)
Greenstick fractures: incomplete fractures of long bones

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29
Q

An infant boy refuses to weight bear with his right limb. Mum complains he is feverish and hard to settle. He has no previous history of trauma. How would you assess and manage this patient?

A

PDx: septic arthritis, osteomyelitis, rheumatic fever
DDx: DDH, NAI, malignancy, transient synovitis; referred pain from abdo/groin

Primary survey if unstable
Assessment
- time course of symptoms
- systemic unwellness: fever, eat/pee/poo/play/sleep
- joint symptoms and signs: hot, swollen, referred pain, limited ROM
- look for NAI signs/symptoms
- examine joint, heart (ARF murmurs), abdo exam - guarding, torsion
- Investigations: joint aspirate MCS, xray, blood cultures, FBC, CRP

Management

  • supportive care: fluids, analgesia
  • IV abx (fluclox)
  • education
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30
Q

An 8 year old girl presents to the ED at 7am complaining of pain in her left hip during walking. She has a history of a cold last week and no history of trauma. She does not have a significant past medical or family history. How would you assess and manage her?

A

PDx: transient synovitis
DDx: reactive arthritis, osteomyelitis, septic arthritis, ARF

Primary survey and resus if necessary
Assessment
- rule out differentials by characterising symptoms, preceding illness and current toxicity
- xray, consider septic bloods

Management: supportive
- analgesia, return to full activity as tolerated (usually by 4 weeks)

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31
Q

A 7 year old boy fell over playing a game in school and lost consciousness for a few seconds. How would you assess and manage?

A

PDx: moderate TBI
DDx: subdural/epidural haematoma

1) Primary survey and resus
- C: do BSL, ECG, VBG
- D: also signs of raised ICP
2) MISTAMPLE (incl bleeding diathesis)
3) Secondary survey
- includes GCS and full neuro exam
- CT brain if any basal skull fracture signs, focal neuro deficits, GCS less than 8, dodgy breathing/airway, amnesia, seizures, known bleeding diathesis
4) More detailed history and exam
5) Supportive care
6) Observe for 4 hours with 30minutely obs (including neuro obs) before discharge home
7) Education and safety net

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32
Q

A 2 year old child was brought into ED with a focal seizure followed by increasing drowsiness and listlessness. On examination she was found to be febrile with a rising blood pressure and falling pulse with papilloedema. What is the acute management of this child?

A

PDx: raised ICP (Cushing’s reflex) secondary to meningitis
DDx: encephalitis, brain abscess, sepsis, tumour, hydrocephalus

Primary survey and resus
A: protect if reduced GCS, loss of protective reflexes
B: O2 if desatting, consider invasive ventilation
C: elevate head of bed, ECG, bloods incl cultures; fluid resus IF NECESSARY, treat fatal triad
D: AVPU, glucose, stat abx (ceftriaxone with dex) and acyclovir, consider head CT if focal neuro sx
E: look for nonblanchable rash, DON’T DO AN LP

History: symptoms, progression, meningitis risk factors
Exam: neuro, raised ICP (bulging fontanelle, fixed dilated pupils, papilloedema, repeated vomiting), other infectious foci

Ongoing management

  • monitoring: obs and neuro obs, EUCs and BSL
  • supportive. fluids, analgesia
  • notification, audiology in 4-8 weeks
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33
Q

A 12 year old boy presents to ED with abdominal pain. He has a history of a viral illness. Discuss your assessment and management. How is the approach different to that of an adult?

A

PDx: mesenteric adenitis (diagnosis of exclusion!)
DDx:
gastro: appendicitis, meckel’s diverticulitis, infective gastroenteritis, IBD, coeliac, malignancy
non-gastro: UTI, EBV

Assessment

  • History of vague, poorly localised pain, anorexia and fatigue, nausea, vomiting, fever, diarrhoea
  • Examine for peritonitis, well localised pain
  • Investigate to rule out differentials: abdo U/S, bloods if unwell (FBC, EUC, LFTs, CRP)

Management: supportive

  • fluids, electrolytes, analgesia
  • complications include suppuration, intussussception, rupture, peritonitis, abscess
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34
Q

An 8 year old girl presents to ED brought in by her mother who is worried she has puffy eyes and has been passing very little urine. Urinalysis reveals protein +++. How would you manage this case?

A

Nephrotic syndrome
PDx: MINIMAL CHANGE DISEASE
DDx: FSGS, membranous amyloidosis (secondary to a malignancy), SLE/other vasculitides, drugs (NSAIDs)

Assessment

  • characterise her symptoms, screen for cancer/inflammatory disease/infections/drugs
  • confirm nephrotic syndrome: urine ACR, urine MCS (check for red cells), UECs, albumin, fasting lipids; consider U/S

Management

  • education
  • steroids, salt restriction
  • consider renal biopsy if no response
35
Q

Osgood-Schlatters

A

.

36
Q

An 11 month old boy presents with a 3 day history of URTI. Now his breathing has become laboured, noisy and difficult. His mother is worried. Another child contact had to be admitted to hospital the previous day. On examination, you hear crackles in lung bases. Discuss your assessment and management.

A

PDx: typical bacterial pneumonia
DDx: atypical pneumonia, viral pneumonitis, TB, bronchiolitis

Primary survey and resus
A:
B: O2 if necessary, consider CPAP, biPAP, ventilation, empirical abx if very unwell (IV ceft and fluclox), try for sputum MCS, NPA and chest xray when stable enough, other bloods include FBC, CRP, UEC, consider urine atypical screen (mycoplasma especially)
C: fluid resus if necessary, septic bloods
D: assess incl glucose
E: temp

More thorough assessment

  • symptoms, infection history, rule out other LRTIs (eg bronchiolitis, TB)
  • assess severity

Management when stable

  • abx if not given (just the typical cover of adult regimens)
  • fluids, electrolytes, analgesia
  • education
37
Q

A 10 year old boy presents with dark coloured urine and oedema of his lower extremities. On physical examination, the patient has a blood pressure of 180/100. His respiratory and cardiovascular examinations are normal. His past medical history is remarkable for a sore throat that was presumed to be a viral infection by his GP 2 weeks ago. How would you assess and manage this patient?

A

Nephritic syndrome!
PDx: postinfectious glomerulonephritis
DDx: IgA nephropathy, goodpasture’s, Alport’s syndrome, rapidly progressive, membranoproliferative

Primary survey and resus if necessary
Assessment
- History: preceding infection (URTI, skin), any hx of ARF/PSGN/RHD, time course, rule out differentials (drugs/meds, other infections, inflammatory diseases, HSP, pulmonary haemorrhage, hearing loss)
- Investigations: urinalysis, ASOT/ADBT, FBC, CRP, UEC

Management

  • Supportive: should self-resolve - treat strep infection if active (abx), reduce hypertension (salt and water restriction, loop diuretics, CCB IF hypertensive encephalopathy), treat kidney failure if it develops (dialysis)
  • If no resolution, look for other causes - nephrology referral, consider autoimmune screen, kidney biopsy
38
Q

Newborn infant presents with projectile vomiting and poor weight gain. Assess and manage.

A 4 week old baby presents with her mother concerned about her vomiting, which is projectile and usually after a feed. His mother said he is not gaining weight, although he is very hungry and on examination he looks slightly dehydrated. What are the differentials for vomiting in the newborn period? Discuss your assessment and management.

A
PDx: pyloric stenosis
DDx: 
- reflux, overfeeding
- gastroenteritis
- food allergy
- obstruction: atresia, malrotation, hernia
- raised intracranial pressure
- sepsis

Primary survey and resus
Assessment
- confirm characteristic presentation: projectile, non-bilious, 2-3 weeks old, always hungry, failure to thrive, palpable peristalsis and ‘tumour’
- rule out differentials: feeding hx, infection, allergy, bilious vomiting
- proper paeds hx including term/prem
- hydration, growth, abdo (feeling for peristalsis and mass, ?surgical cause)
- confirm diagnosis with abdo U/S and check acid-base and UECs

Management

  • supportive: fluids, electrolytes, monitoring
  • surgical: pyloromyotomy: Ramstedt’s procedure (open) or lap
39
Q

A 7 year old Indigenous child presents with fever and polyarthritis. You note a cardiac murmur. Discuss your assessment and management.

A

PDx: acute rheumatic fever
DDx: infective endocarditis

Primary survey and resus if necessary
Assessment
- confirm ARF (Jones criteria) with hx of preceding GAS illness, skin (erythema marginatum, subcutaneous nodules), Sydenham’s chorea
- rule out IE (Duke’s criteria): history of CHD, recent surgery esp dental, vasculitic/immunologic phenomena, clubbing
- Investigations: ECG (esp if no carditis), ASOT/ADBT, FBC, CRP, blood cultures (2 enough in kids), echo, EUCs, LFTs
- Consider CXR: ?heart failure

Management

  • joints: NSAIDs
  • heart: treat heart failure
  • underlying infection: ben pen IV (oral abx for 10 days instead if good compliance)
  • secondary prophylaxis: ben pen monthly until 21 years old (or 5 years after last attack)
  • monitor valve impairment with echo
  • hygiene, isolation etc
40
Q

A 16 year old obese boy presents with pain in the right knee and hip. He walks into your practice with a limp. How would you assess and manage this child?

A

PDx: SUFE
DDx: septic arthritis, inflammatory arthritis, stress/overuse fracture

Assessment

  • confirm diagnosis: pain a joint above and below, irritable hip, worse with exercise, may be externally rotated
  • rule out differentials: any other joints involved, onset of pain
  • investigations: frog leg lateral and AP xray

Management

  • fixation (osteotomy if big slip)
  • weight loss
41
Q

A 9 year old boy presents with recurrent afebrile seizures which are focal in onset then generalize to grand mal seizures. This time he presents to the ED with a 20 min seizure. How would you manage this child?

A

PDx: status epilepticus due to epilepsy
DDx: underlying encephalitis, SOL

Primary survey and resus
A: place in recovery position
B: O2 via NP, consider bag-masking
C: ECG, insert cannulae if possible and draw bloods (FBC, CRP, UEC, CMP, BSL, LFTs, coags, antiepileptic levels if taken) and give IV lorazepam (IM midaz or rectal loraz if no IV access) and then fosphenytoin if no response to benzo. Will need to try eg propofol infusion if no resolution by 30 minutes of seizing.
D: serial GCS, EEG, pupils, BSL
E: look for cause - temp, rash etc

Assessment once stable
History
- seizures, treatments
- potential causes (raised ICP sx, infectious sx, head trauma, changes in meds, FHx)
Exam
- vitals, GCS, hydration, post-ictal changes (pupillary asymmetry, motor weakness)
- potential causes: meningism, raised ICP, trauma
Investigations: bloods above - consider urine tox, MRI brain, EEG

Management:

  • education: avoid triggers, keep anti-epileptics, first aid, activities to avoid/be closely supervised during
  • treat underlying cause if there is one
42
Q

16 year old boy presents with scrotal swelling and pain. Assess and manage.

A

PDx: testicular torsion
DDx: torsion of testicular appendage, epididymoorchitis; incarcerated hernia, scrotal trauma

Assessment

  • how quickly do I need to act: time of onset, vitals
  • confirm diagnosis: sudden onset, incredible pain, previous episodes that have self-resolved
  • rule out differentials - hx of trauma, hernia known, sexual history + STI symptoms
  • examine, expecting high testis, transverse lie, hard of palpation, loss of cremasteric reflex; check for STI lesions, hernia
  • confirm with duplex ultrasound (CLiNicAl diAgnOSiS); rule out differentials with urine STI screen

Management

  • orchidopexy within 6 hours
  • analgesia, fluids etc
43
Q

A 4 year old boy presents with a limp while walking. Examination reveals limited range of movement. Assess and manage.

A

PDx: transient synovitis (Dx of EXCLUSION)
DDx: trauma (?NAI), DDH, Perthes, infection, malignancy, bleeding diathesis, juvenile arthritis (referred from abdo unlikely given ROM)

Assessment

  • confirm characteristic presentation: pain, limited ROM but otherwise well
  • rule out differentials
  • examine hips, other signs of infection/malignancy, leg length, trendelenberg
  • consider xray, others as per hx

Management

  • transient synovitis is conservative: NSAIDs, return to full movement as tolerated
  • otherwise treat cause
44
Q

Angus is a 13 year old boy sent to hospital by his gastroenterologist because of his ulcerative colitis. He was first diagnosed 6 months ago. Since then he has been managed on steroids. He had his first hospital admission 6 weeks ago. Since then he has been weaned off his steroids. In the week prior to seeing his gastroenterologist, Angus has had bloody diarrhoea and abdominal pains. Discuss options for his management.

A

PDx: UC recurrence
DDx: infective gastro incl c diff

If unstable, primary survey and resus - hypovolaemia, anaemia, toxic megacolon and sepsis

If stable:
Assessment
- symptoms - paediatric UC activity index (no. of stools, abdo pain/anaemia/fever/tenesmus)
- disease course and management thus far - esp rectal vs extensive?
- rule out ddx
- abdo and PR exam
- consider AXR esp if worried about toxic megacolon
- faecal calprotectin, FBC, CRP, stool MCS + c diff toxin

Management

  • supportive care: fluids, electrolytes, analgesia
  • restart therapy: steroid (quick acting) plus 5-ASA - if steroids can’t be weaned, consider immunotherapy eg infliximab or colectomy
  • start maintenance therapy: ste
  • treat anaemia if present
  • education, counselling
  • monitor for CRC, extra-intestinal manifestations, psych sequelae, growth sequelae
  • immunise!
45
Q

A 9 year old girl presents with sore throat for 3 days and difficulty swallowing. On examination, her pharynx is erythematous and tonsils are enlarged. Discuss your assessment and management.

A

URTI: pharyngitis, tonsillitis

  • bacterial
  • viral

Primary survey and resus:

  • hypovolaemia
  • quinsey causing airway obstruction

History

  • determine reasons to give abx: high risk community, RHD, scarlet fever, exudative, high fever, tender cervical lymphadenopathy, tonsillar exudate and the absence of cough
  • infection hx
  • screen for complications
  • investigate for GAS and EBV if unwell

Management

  • supportive usually: analgesia, antipyretics
  • abx are pen V
46
Q

A one year old child presents with fever without a focus. He has leucocytes and nitrites on his dipstick. Discuss your assessment and management.

A 2 week old baby boy presents with fever, unsettled and a decrease in feeding. Suprapubic aspirate of urine shows an increase in WCC. How will you manage?

A

PDx: UTI
DDx: false positive urinalysis - check for other sources of infection (incl malignancy, meningitis, IE, viral infections, autoimmune)

Once confirmed on SPA…

If unstable, primary survey and resus
- abx for sepsis of unknown origin is cefotaxime and amp in less than 2 months; ceft gent vanc in more than 2 months old

Assessment

  • History: symptoms, toxicity, dehydration, underlying predisposition to UTI, rule out other infections
  • Exam: toxicity, fluid status, general exam
  • Investigations: urine MCS, bloods if unwell

Management

  • supportive care: fluids, analgesia, antipyretics
  • abx: keflex/bactrim/augmentinfor cystitis; gent and amp for pyelo (or underlying predisposition)
  • F/U: renal U/S four weeks after and if abnormal, DMSA/MCUG
47
Q

A 1 year old presents with fever and no focus. He is found to have + leukocytes and nitrites on dipstick and an MSU shows a UTI. Discuss your management. If he is subsequently found to have grade IV VUR, how would you follow up this patient and what are the possible long-term complications?

A 3 year old boy with his third UTI in 12 months. Discuss your assessment and management.

A

UTI

Assessment

  • predisposing factors: prematurity, myelomeningocoele, bowel and bladder dysfunction (including shown by enuresis, daytime dribbling, frequency/infrequency, withholding patterns, urgency, incontinence)
  • check for systemic predisposing factors: DM, immunosuppression (cancer, drugs)
  • imaging: renal U/S, MCUG when asymptomatic, DMSA 4-6 months after the infection

Management

  • education
  • monitoring for UTIs
  • monitoring for CKD - growth, BP, urinalysis
  • consider abx prophylaxis because grade IV

Long term complications

  • recurrent UTIs
  • renal scarring
  • chronic kidney disease
48
Q

chickenpox

A

DDx
- herpes simplex

Assessment

  • initial prodrome of slight fever, malaise, anorexia
  • typical macular rash first on trunk then in extremities, becomes papular then vesicular, pustular, crusty
  • screen for complications: meningoencephalitis, impetigo, pneumonia, HSP

Management: supportive

  • parental education
  • dressings, moistureiser, regular bathing, gloves to prevent scratching (antihistamines if severe)
49
Q

An 8 year old girl is referred by her class teacher who noticed she has become highly inattentive in class with multiple “daydreaming” episodes where she seems absent and stares away. Her school work has also started deteriorating. How would you assess and manage her?

A

Absent seizures
DDx: ADD

Assessment

50
Q

Cody is an 8 year old boy referred to paediatrics clinic from general practitioner because of disruptive behaviour at home and school. His mother recalls that Cody has been hyperactive since a toddler. Teacher reports that he does not sit still in class and interrupts frequently. Discuss approach to management.

A

PDx: ADHD
DDx:
- medical: hearing/vision problems, absence seizures, sleep disorders, hyperthyroidism
- neurodev: autism, language/speech delay, intellectual disability
- social: stressors, abuse

Assessment

  • characterise symptoms: at home, at school, in other contexts
  • check for testing for med diseases
  • check developmental history and any developmental insults
  • screen for social issues
  • check for PMHx/FHx of cardiac disease because worried about long QT with the meds
  • examine growth, dev, hypo/hyperthyroidism, neuro signs
  • use validated scales to diagnose (eg Connor Rating Scale)
  • hearing and visual testing, IQ and achievement testing

Management

  • education
  • non pharm: educational support, behavioural modification, psych counselling
  • pharm: stimulants (eg methylphenidate) - start low, go slow
  • monitor - every 3-6 months after initial stabilisation: growth and other side effects, relationships, school
51
Q

A 2 year old child presents with no speech. He is obsessed with Thomas the Tank engine and is distressed by change in routine. What features distinguish autism from isolated speech delay and global development delay? How would you assess and manage this child?

A

Distinguishing autism, speech delay, global developmental delay:

  • speech affected: in all
  • motor affected: only GDD
  • social: milestones affected in autism and GDD, social effort and responsiveness only affected in autism
  • behaviours: only in autism

Assessment

  • Characterise symptoms: check DSM criteria (social, communication, behaviour), check developmental domains
  • Rest of paeds history, esp perinatal issues, growth and genetic conditions in family (fragile X, tuberous sclerosis, angelman syndrome, inborn errors of metabolism)
  • ADOS, PEDS: formal developmental, autism, psych assessment (OT, speech path, ed and dev psych)

Management: MDT, individualised
- early intervention - behavioural and educational; family; school and community

52
Q

A 3 year old with quadriplegic CP has severe weakness and developmental abilities of a 2 month old child. She comes to clinic for review. How would you manage this patient?

A

CP

  • spastic (70%)
  • dyskinetic (10-15%)
  • ataxic (<5%)

Standard history of CP and effects incl developmental and on family

Management: MDT-> early intervention
FEEDING
- FTT: consider NG, gastrostomy
- GORD: upright after feeding, PPIs
AUTONOMIC
- constipation: fluid, fibre
- drooling: speech path, antichol
- incontinence: behavioural training, incontinence aids if necessary
MUSCULAR
- contractures: physio, casts to increase joint range
SCHOOLY
- poor hearing and vision: testing
- poor cognition and language: community-based school program
PSYCHOSOCIAL
- family coping: psych, volunteer help, carer’s allowance

53
Q

A 2 year old presents with a history of poor growth from 12 months of age. His parents mention he has 3-4 foul-smelling stools a day. What is the likely diagnosis and investigation

A

malabsorption
PDx: coeliac
DDx: infective gastro (chronic, parasitic), milk/soy intolerance, CF, IBD rare

Assessment

  • characterise symptoms and food-relation; any pulmonary symptoms?
  • screen for coeliac crisis: explosive watery diarrhoea, marked abdo distension, dehydration and electrolyte abnormalities
  • check for risk factors: other autoimmune conditions (thyroid, DM) and chromosomal (Down, Turner)
  • growth, abdo exam, pallor, ‘large abdomen with wasted buttocks’
  • diagnose with screening coeliac antibodies (check IgA levels if negative) then duodenal biopsy

Management

  • gluten free diet
  • supplementation as necessary: Fe, vitamin D, Ca
  • monitor for complications: GI lymphoma and carcinoma
54
Q

2 year old presents with persistent cough for several months, associated with bulky frothy stools and feeding intolerance. Discuss how you would investigate and manage this child.

A 3 week old baby has had a positive newborn screening test for CF and is found to be homozygous for ∆508 mutations. Explain your management. How would you confirm the diagnosis? How would you explain to the parents what CF is and the risk to future children? What are the treatments and long term outcomes?

A

PDx: CF
DDx: coeliac, food intolerance (milk, soy), chronic gastro

Assessment

  • symptoms; associated symptoms eg food-association, change in bowel habit
  • perinatally: delayed passage of meconium, heelprick
  • family history/personal autoimmune history
  • examine for malnutrition, crackles + clubbing, abdo masses
  • confirm diagnosis with sweat test
  • check for sequelae: vitamin ADEK, UEC

Management: MDT

  • lung: physio, NS nebs, prophylactic antibiotics; lung transplant once lung failing
  • pancreas: creon, insulin
  • treat deficiencies
  • psychosocial support (incl fertility concerns in the future)
  • monitor for progression

Implications

  • parents: future children have 1/4 chance
  • children: increased risk of infections, bronchiectasis, respiratory failure, malabsorption and malnutrition, diabetes, pancreatic failure, osteoporosis, neurological deficits
55
Q

Delayed puberty

A

Definition: puberty late
PDx: constitutional
DDx:
- sick: chronic illness, low BMI
- gonads off: congenital gonad-issue (Turner, Klinefelter), acquired gonad-issue: chemo, rtx, trauma
- hypothal/pit off: Kallmann syndrome, hypothyroidism, brain issues

Assessment

  • check for causes
  • FHx
  • examine to determine stage of puberty (Tanner stages), neuro exam, dysmorphic features
  • Ix: bone age LH and FSH to see if primary or secondary (karyotyping if primary), prolactin, TFTs

Management

  • most will be constitutional/congenital GnRH def: watchful waiting vs sex steroids
  • otherwise treat underlying cause
56
Q

Developmental milestones

A

Personal social:

  • 9 months: stranger anxiety
  • 2 years: feeds/drinks fine
57
Q

A two year old is brought in by mum who is worried he is not speaking and does not understand “wave bye-bye”. He sat at 11 months and walked at 18 months. His vision and hearing are fine. His family is bilingual. What advice would you give, and how would you assess the patient? What signs would worry you?

A

PDx: slightly delayed language development due to bilingual family/stress etc
DDx: language delay, global developmental delay, autism

Assessment

  • developmental milestone achievement and/or regression
  • social, behavioural
  • perinatal insults (including prem), family history, dysmorphia
  • rest of history incl psychosocial
  • growth, neuro, gross dev screen (observing free play)

Management

  • formal assessment with PEDS
  • early intervention, MDT -> speech path, OT, PT etc
58
Q

A 5 month old presents with floppy muscle tone and inability to lift his head from the bed in the prone position. You notice he does not fix and follow reliably. How would you assess and manage this patient? Also mention services available for developmentally delayed children.

A

PDx: motor delay, ?social delay

Assessment

  • developmental achievement and regression
  • perinatal/postnatal insults, dysmorphia, family history
  • psychosocial concerns
  • gross dev assessment (free play), growth, neuro
  • formal assessment: PEDS

Management: MDT

  • early intervention
  • services: Parent Line NSW, Early Links Coordiantors
59
Q

A newborn girl is noticed to have dysmorphic features consistent with Down’s syndrome. How would you assess and manage this patient?

A
PDx: Down syndrome
-neuro - dev delay, behavioural, atlantoaxial instability; 
- eyes - cataracts, strabismus, 
- cardiac: ASD, VSD, ToF
- GI: atresia, Hirschsprung, coeliac
- haem: leukaemia
DDx: just dysmorphic

Assessment

  • dysmorphic features: low flat nasal bridge, short nose, indistinct philtrum, thin upper lip, epicanthal folds and slanted palpebral fissures, small eye opening, small midface
  • other features: hypotonia/absent moro, CHD, growth
  • perinatal hx: screening, past/family history, mode of conception
  • confirm dx: karyotyping
  • screen for complications: echo, AXR, hearing and visual screen

Management

  • warm, supportive, encouraging manner
  • genetic counselling
  • psych and social support
  • educate about health risk management: paed follow up, hearing and vision reviews, TFTs at 6 months and then 12 monthly, coeliac screening, PT/OT/Speech path referral as developmentally appropriate, paed cardiologist if CHD
60
Q

A mother presents to you with her 7 year old son who is “always clumsy”. He dislikes PE and has a funny gait and run. He started walking at 20 months and was delayed with his speaking. What are your provisional and differential diagnoses? How would you manage this boy?

A

Global developmental delay

Assessment

  • characterise motor issues (ataxia, spasticity, weakness) and development/regression
  • characterise speech issues and development/regression (dysphasia vs dysarthria)
  • assess other developmental domains and functional impact, predisposing factors (syndromes, insults, FHx)
  • MDT involvement, treatment so far
  • check growth and neuro + dev screen
  • Investigations as per history eg genetic testing, CK/EMG/genetic testing/?muscle biopsy if myopathic

Management: MDT

  • PT/OT to improve walking and functionality
  • speech path for speech
  • school + community programs for education/socialisation
  • social work to link in to services, financial assistance, respite care
  • pred + close monitoring if DMD
61
Q

Jessica, 9, and her mother present to you because of faecal soiling. Her mother feels that she is not constipated because Jessica has big stools. Her bowel motions are, however, infrequent. Her faecal incontinence is affecting her schooling because other children avoid her. How would you manage this situation?

A

Encopresis
PDx: chronic functional constipation
DDx: organic constipation (Hirschsprung, anorectal malformation, hypothyroidism, opioids), neurodev (behavioral problems, enuresis)

Assessment

  • characterise encopresis
  • screen for organic constipation and other behavioural symptoms
  • paeds hx
  • growth, abdo DRE (?blast sign)
  • investigate only if suspicious eg AXR, rectal biopsy, TFTs

Management

  • education
  • non-pharm = attention to toilet, fluid + fibre + exercise
  • pharm = disimpaction and long continue stool softener (at least one soft stool per day)
62
Q

Montana a 6 month old infant presents to clinic because the maternal and child health nurse was worried about her growth. On examination and measurement you find Montana’s weight has crossed 2 major centiles in the last 3 months. Discuss your approach to management.

A

Failure to thrive
DDx:
- inadequate intake: inadequate nutrition (incl error in formula dilution, neglect, parental mood disorder), early or delayed solids, breastfeeding difficulties
- poor absorption: coeliac, CF, CMPI
- excessive use: chronic disease (CHD, CF, DM hyperthyroidism)

Assessment

  • red flags: evidence of abuse/neglect, parental psychosocial issues eg psych illness, ID, D&A, DV, social isolation, poor attachment
  • characterise growth and dev
  • feeding hx
  • pmhx and perinatal hx
  • psychosocial factors + stressors
  • growth plotting, signs of malnutrition and chronic illness (chest, abdo)
  • observe a feed
  • examine child’s interaction with parents, general behaviour and any signs of NAI/neglect
  • first investigative screen = FBC, Fe, UEC, CMP, LFTs; coeliac screen, TFTs, urine + stool MCS

Management

  • treat underlying condition
  • education
  • eating diary
  • counsel on improving feeding technique
  • MANDATORY REPORTING if abuse
  • F/U
63
Q
A 6 year old boy is brought into the clinic as his parents are concerned about his height. He is the smallest in his class and his height is <3rd centile. Discuss how you would manage this child.
A 12 year old boy presents because his parents are concerned about his height and self-esteem as a result. His parents wish to know the cause and if there is anything to help him grow. How would you assess and manage?
A

Short stature
DDx
- normal: familially short, constitutional delay, congenital conditions, idiopathic
- path: malnutrition, chronic disease, drugs

History + Exam

  • growth, changes, ?puberty
  • family history
  • stressors, chronic disease, nutrition, drugs
  • genetic conditions/perinatal issues
  • examine growth + growth velocity, look for dysmorphic features, ?abuse

Investigations

  • bone age: if normal, probs not pathological
  • FBC, EUC, LFTs, CRP, Fe
  • coeliac, TSH
  • consider CF, IGF and karyotyping

Management

  • treat underlying cause
  • consider GH if deficiency- height <1st centile, low growth velocity and early bone age, no contraindications
64
Q

A 6m old presents with no previous immunizations because her parents are concerned about risk of allergic reactions. Their friend’s child had screaming for >3 hours and the LMO said further immunizations were contraindicated. Discuss how immunizations work and the contraindications to vaccinations. Discuss side effects of immunizations and risks of brain damage.

A

Immunisation counselling

MoA

  • immune system
  • vax contents
  • immunisation
  • prevention better than cure esp because many vax diseases are extremely dangerous
  • ingredients: adjuvants, diluents, stabilisers, preservatives, trace components

Contraindications

  • anaphylactic reaction (usually abx/gelatin/egg)
  • encephalopathy within 7 days of a previous DTP-containing vaccine
  • immunocompromise/malignancy (can’t get live)
  • pregnancy (rubella, varicella)

Side effects

  • erythema, fever, mild rash
  • headache, diarrhoea, stomach discomfort, restlessness

Risks of brain damage

  • <1/100 000
  • do not cause autism
65
Q

A 7 year old girl presents with a neck lump. Discuss your assessment and management.

A

Neck lump
DDx
- skin: sebaceous cyst, abscess etc
- lymph node (infection local/systemic OR malignant OR sometimes Kawasaki)
- congenital cysts (branchial, thyroglossal)

Assessment

  • hx of lump
  • symptoms of infection/malignancy
  • symptoms of Kawasaki: rash, conjunctivitis, strawberry tongue
  • examine lump, haem screen
  • ix IF indicated -bloods, consider microbio (serology for CMV, monosport, toxo), ?biopsy

Management

  • supportive for infections
  • chemo for cancer
66
Q

Steven is a 10 year old boy who presents with a history of recurrent chest infections. Mother is worried about cystic fibrosis. On further history and examination he has already been test and was definitively negative. You reassure her that he has a post-viral cough and not CF. As they leave, his mother comments that Steven wets the bed every night. Discuss your approach to management of his enuresis.

A

PDx: primary monosymptomatic
DDx
- secondary (to social stress)
- non-monosymptomatic enuresis - with lots of urinary tract sx eg urgency, daytime incontinence, hesitancy, straining, weak stream
- med conditions: DM, UTI, neurogenic bladder

Assessment

  • characterise enuresis: how long, ?other LUTS
  • look for other causes (DM, UTI, neuro)
  • look for contributory factors: constipation, social stressors
  • examine for medical causes
  • consider urinalysis and U/S

Management

  • education
  • voiding diary
  • behavioural: positive reinforcement, well-hydrated, voiding prior to bedtime
  • nextline: alarm system, bladder training, consider desmopressin if refractory

*<7yo should spontaneous resolve

67
Q

A 20 month old is brought into the ED by her mother, who claims she fell out of her cot 12 hours ago and seems to have broken her leg. The child appears miserable, dirty and ill cared for. Initial examination findings reveal multiple bruises on the back and body including the back of her head. X-ray reveals a spiral fracture of the femur. How would you assess and manage her?

A

NAI

Primary survey and resus
History
- get a thorough history (MIST) from the mother, and any one else ideally separately and look for inconsistencies in the story and between stories
- get thorough psychosocial hx
Exam
- observe interaction between child and mother
- look for signs of neglect and abuse - bruising, burns, lacerations, fractures -> look everywhere, incl head cavities, perineum
- growth and dev
Inv
- skeletal survey, consider CT brain

Management: MDT

  • treat current injuries
  • report to FACS: Child Protection Helpline if ?immediate risk
  • consider informing parents
68
Q

A 9 month old is noted by the GP to be very pale. The parents are not sure of the duration but do not report any recent change. The infant is generally well but is a little lethargic and irritable. What are the possible differential diagnoses? How would you assess and manage this child?

A
Pallor
DDx: anaemia
- deficiency (Fe, B12, folate)
- leukaemia (bone marrow suppression)
- sickle cell, thalassaemia
- haemolytic anaemia

Assessment

  • history of pallor; perinatal hx esp jaundice
  • sx of malnutrition (growth, GI disease, bleeding), cancer
  • diet
  • FHx
  • haem exam -?extramedullary haematopoiesis
  • Ix: FBC, Fe studies, B12 and folate, consider haemolysis screen
Management: treat cause
-Fe def: dietary advice; supplementary iron
- thalassaemia:
1) everyone gets folic acid
thal minor: fine otherwise
thal major/intermedia: 
2) transfusions and iron chelation - regular if thal major, as needed with thal intermedia
3) consider HSCT for thal major
69
Q

A concerned mother presents to her GP for information about SIDs and how she can reduce her child’s risk of this condition. How would you manage this situation?

A

SIDS
- Assessment: full paeds hx, acute life-threatening events, risk factors (prem, LBW)
- Explain condition: sudden death where postmortem fails to identify cause
- Management:
=> supine sleeping
=> don’t cover head, not wrapped too tightly
=> sleeping separately
=> reduce smoking/drug/alcohol
=> immunise
- breast feeding, dummies, flights, apnoea monitors, mattresses make no difference

If it happens:

  • support groups
  • need to inform coroner
70
Q

A mother presents to you with her 6-year old son with concerns he is of short stature. His antenatal and post-natal histories have been normal to date. On physical examination the boy appears to have a large head, is on the <3rd centile for height with enlarged wrists and ankles. How would you assess and manage him?

A

Rickets:
PDx: inadequate vit D or Ca -> usually dietary (reduced sun, reduced activation from renal/hepatic disease)
DDx: renal phosphate wasting

Assessment
- paeds hx
- other signs of rickets: delayed closure of fontanelles, parietal and frontal bossing, widening of wrist, rachitic rosary, bowing of legs
- hx of DDx
- growth, other signs of rickets
- Investigations
FIRST: ALP, xrays to confirm rickets
THEN: PTH, CMP to work out if Capaenic or Phpaenic (PTH high in Capaenic)
IF Capaenic: vit D (25-vitD and 1,25vitD)

Management

  • non-pharm: education -> sun, diet
  • pharm: vit D supplementation; Ca if necessary
  • F/U: repeat after 3 months if mod-severe
  • specialist review if not responding
71
Q

The mother of a newborn has overheard nurses saying that a “baby check” needs to be done, and she would like to know what this means. What is the difference between newborn screening and a baby-check? What is SWISH?

A

Baby check

1) Observation
2) Auscultation - heart
3) Head and neck: sutures, eyes (red reflex), ears, mouth (sucking, cleft lip/palate), neck (cysts)
4) Chest: tachypnoea/resp distress
5) Abdo + genitalia: masses, umbilical erythema/warmth, femoral pulses, descended testes, anus and spine
6) Limbs: tone, Moro, Barlow, Ortolani, all digits

Newborn screening: heel prick (CF, PKU, galactosaemia, congenital hypothyroidism, rare metabolic things)

SWISH (Statewide Infant Screening - Hearing): pick up congenital sensorineural hearing loss in <1 month olds -> automated auditory brainstem response testing

72
Q

A mother presents with difficulties breastfeeding and asks about formula feeding. Discuss your approach to this problem. Discuss benefits of breastfeeding and bottle-feeding with the mum.

A

Breastfeeding

Non-judgemental

1) Assessment
- difficulties: milk production, sore nipples, health conditions (infection, drugs), social reasons, infant technique, infant conditions (prem, hypotonia, ankyloglossia, cleft lip/palate, CHD)
- demonstration of technique: mother alert to cues, infant positioned correctly -> effective latch, rhythmic suck
2) Counsel on benefits of breastfeeding
- baby: nutrition, infection, long term health, bonding
- mother: risk of cancer and OP, pre-pregnancy weight return quicker, bonding
- family: cost, contraception
3) Counsel on benefits of formula
- baby: nutrition
- mother: psychological wellbeing
4) Treat issues
- nipples: moisturiser
- engorgement: frequent feeding/pumping
5) Refer to lactation support service

73
Q

A neonate fails to pass meconium within the first 48 hours of life. How would you assess and manage this child?

A

Delayed passage of meconium
PDx: Hirschsprung
DDx: ileus -> sepsis, drugs, hypothyroidism; mechanical -> volvulus, congenital anatomical obstruction

Concerns

  • could reflect significant underlying pathology
  • could lead to NEC

Assessment

  • perinatal hx esp PREM, sepsis, hypotonia, drugs, fhx of congenital anatomical issues, abdo distension, bilious vomiting
  • examine for toxicity and GI (?blast sign)
  • bloods, AXR, barium enema (Hirschsprung gold standard is rectal biopsy

Management

  • Hirschsprung’s: resection
  • Anatomical abnormality: surgery
  • Ileus: treat cause
74
Q

What is hypospadias and what is the management of this problem?

A

Hypospadias
- def: incomplete development of the anterior urethra due to failure of the urethral folds to unite over and cover the urethral groove -> urethral opening on the underside of the penis

Assessment

  • PHx of congenital anomalies, cryptoorchidism
  • FHx
  • examine penis: incomplete foreskin, distal urethral pit on the glans
  • examine testes (?disorder of sex differentiation)
  • consider U/S if ?DSD

Management

  • don’t circumcise
  • surgical repair in first 3-6 months
  • monitor for urethral strictures, fistula, discomfort from temporary bladder catheter (while repair heals)
75
Q

A premature infant presents with mild bleeding per-rectum. What is your provisional diagnosis? Briefly describe your management. What problems are present in premature babies?

A 2 week old pre-term baby comes in with abdominal distension, inability to tolerate feeds, apnoeas, lethargy and a fluctuating temperature. How would you assess and manage this child?

A

PDx: NEC
DDx: obstruction -> enterocolitis; infective enteritis; CMPA

Assessment

  • sx esp NEC severity
  • prem, circumstances around birth (any complications that would lead to NEC)
  • any risk factors for obstruction
  • diet
  • examine for toxicity, GI exam
  • bloods: FBC, CRP, UEC, CMP, LFTs, VBG
  • AXR (avoid barium enema)
  • consider stool MCS

Management

  • education
  • supportive care: fluids, thermoneutral environment, nutrition, NG, monitoring
  • abx
  • surgical if necessary: resection

Problems in prems

  • head: IVH
  • eyes: retinopathy of prem
  • CV: PDA, hypotension
  • resp: RDS, BPD, apnoea of prem
  • GI: NEC
  • metabolic~: hypoglycaemia, hypothermia, electrolyte derangement, anaemia of prem
  • infections
76
Q

The midwives call you because a neonate is cyanotic and not responding to positive pressure ventilation. Discuss your assessment and management.

A

PDx: cyanotic heart disease (ToF, TGA, tricuspid atresia)
DDx: severe respiratory disease - RDS, TTN, mec aspiration, pneumothorax; sepsis

Call for help
Primary survey and resus
- A: neutral position, clear secretions, consider intubation
- B: ausc, O2, CPAP, nIPPV, consider mechanical => CXR
- C: auscultate and assess (incl ECG), treat hypotension as per cause (fluids if hypovolaemic, inotropes if cardiogenic), abx (amp + gent), chest compressions if HR <60 => BLOODS incl cord gas
- D: don’t forget glucose, as well as AVPU and pupils
- E: check temperature etc

Simultaneous AMPLE

  • perinatal hx: term vs prem, APGAR, therapies incl steroids/opioids, any insults, known disease esp CHD, any fhx of congenital disease esp CHD
  • rest of hx

Definitive management

  • PGE1 if duct-dependent
  • organise transfer to Melbourne
  • support baby
  • heart surgery in Melbourne
77
Q

A 2 month old child presents with persistent jaundice since the neonatal period. How would you manage this baby initially? List possible causes. On examination he has pale stools and bruises visible on his body. What would be the cause and what complications to examine/investigate for? Explain to parents what your concerns are.

A

Obstructive jaundice
PDx: biliary atresia
DDx: TORCH/UTI, inborn errors of metabolism, CF

Assessment

  • characterise HoPC - biliary atresia babies are term, thriving and then develop jaundice, may have other congenital defects
  • assess perinatal hx and insults
  • ask about DDx
  • risk factors: prematurity, sepsis, PN
  • confirm obstructive jaundice and assess: LFTs, UEC, CMP, coags, FBC
  • imaging: U/S, hepatobiliary scintigraphy, liver biopsy, intraop cholangiogram
  • rule out ddx as per hx eg urine MCS, TORCH screen, septic screen

Management

  • Kasai procedure, abx for 1 year postop
  • ursodeoxycholic acid, vitamin supplementation, nutritional supplementation
  • consider liver transplantation if jaundice persists

PHYSIOLOGICAL JAUNDICE

  • plot
  • phototherapy
  • exchange transfusion if high risk
78
Q

A baby is born at 30 weeks gestation and is grunting with increased RR for age. What kind of problems do premature babies face, and how would you manage this presentation? How would you prevent this problem?

A

PDx: RDS
DDx: sepsis, CHD

Call for help
Primary survey and resus
A: neutral position, consider I+V
B: assess, CPAP, ?nIPPV, ?I+V
C: assess circultation; auscultate ?CHD; BP support if necessary (fluids then inotropes) => BLOODS
D: CHECK GLUCOSE
E: thermoneutral environment, consider other sources of sepsis eg NEC

Simultaneous AMPLE

  • hx of sx incl mx
  • perinatal hx: age and delivery, prenatal mx (incl steroids), prenatal insults and ix results (esp morphology scan and GBS)
  • past hx esp congenital

Definitive management RDS

  • consider AXR to confirm diagnosis
  • if FiO2 fine on CPAP, continue on CPAP
  • if FiO2 is high, intubate and give exogenous surfactant; check FiO2 again on ABG and consider whether they need another surfactant dose, otherwise extubate to CPAP
  • consider transfer to Melbourne

Prem babies

  • head: IVH
  • eyes; retinopathy of prematurity
  • CV: PDA, hypotension
  • resp: RDS, BPD, AoP
  • GI: NEC
  • metabolicky: hypoglycaemia, hypothermia, electrolyte disturbance, anaemia of prem
  • infections
79
Q

A newborn is found to be very unwell and floppy: unusual crying, cyanosis, cool peripheries, grunting and tachypnoeic. Describe your acute management.

A

PDx: sepsis
DDx: RDS, CHD

Call for help
Primary survey and resus
A: neutral position, consider I+V
B: assess, CPAP, ?nIPPV, ?I+V
C: assess circultation; auscultate ?CHD; BP support if necessary (fluids then inotropes) => BLOODS (FBC, CRP, UEC, LFTs, blood cultures)
D: CHECK GLUCOSE
E: temp; thermoneutral environment, consider other sources of sepsis eg NEC

Simultaneous AMPLE

  • hx of sx incl mx
  • perinatal hx: age and delivery, prenatal mx (incl steroids), prenatal insults and ix results (esp morphology scan and GBS)
  • past hx esp congenital

Definitive management sepsis

  • supportive care
  • broad spectrum abx: amp + gent
  • consider transfer to Melbourne if no improvement
80
Q

A 7 year old boy is brought in with a painless rash. He was found to have diffuse petechial rash all over his body, non-blanching and red pinpoint macules. He is haemodynamically stable, feeling well with no fever, nausea or neck stiffness. How would you assess and manage this child?

A

PDx: ITP
DDx: haem malignancy (leukaemia, lymphoma, metastatic to bone marrow), infection (sepsis, enterovirus, meningitis), post-infectious (HSP)

Primary survey and resus if necessary
Assessment
- History: of symptoms, any bleeding sx, any haem sx, any cancer sx, infectious sx (or preceding infection), viral exanthem sx or HSP sx
- Exam: characterise the rash, look for bleeding, haem organ exam
- Investigations: FBC and peripheral smear, urinalysis

Management

  • Education
  • Conservative management for a month: rest, avoid contact sports, avoid NSAIDs and immunisations
  • If inadequate improvement, pred firstline then IVIg secondline
81
Q

A 5 year old boy presents with a 3 week history of pallor, irritability, peri-orbital bruising, bone pain and a limp. He was pale and had bilateral peri-orbital bruising and swelling. A mass was palpable around his jaw. He walked in with a limp in his right leg. His BP is 150/90mmHg. A large right-sided abdominal mass was palpable.

A

PDx: Neuroblastoma - metastasised to bone
DDx: Nephroblastoma, hepatoblastoma, lymphoma

Assessment

  • characterise symptoms incl opsoclonus-myoclonus, VIP diarrhoea
  • rule out differentials: haem cancer, B symptoms, haematuria, bleeding (vWD?)
  • stage clinically
  • assess for risk factors: FHx, neurofibromatosis
  • FBC, EUC, LFTs, urine/serum catecholamines (VMA, HVA), ferritin, LDH
  • U/S
  • biopsy - can be of bone marrow

Management

  • stage with CT/MRI, bone scan
  • surgical resection if low-risk
  • add chemo, immunologic therapy, stem cell rescue, radiation if higher risk
  • long term follow up
82
Q

A 10 year old boy presents with a 4 month history of increasingly severe headaches. It is associated with nausea, is worse in the mornings, diplopia, clumsiness and deteriorating school performance. What are your provisional and differential diagnoses?

A

PDx: medulloblastoma
DDx: other childhood CNS cancer (glioma - glioblastoma, astrocytoma, oligodendroglioma, ependymoma), benign intracranial hypertension

Primary survey if necessary

Assessment

  • characterise symptoms
  • raised ICP symptoms
  • cancer sx incl from other sites
  • risk factors: FHx, neurofibromatosis, tuberous sclerosis
  • neuro exam (esp CN, cerebellar), raised ICP, vitals
  • MRI brain, consider LP for leptomeningeal disease

Management
- surgery with chemo

83
Q

A 5 year old girl presented with a week history of tiredness, lethargy, weight loss and abdominal pain. In the last 2 weeks she has developed abdominal distension and breathlessness. Two days before presentation she developed a high fever. What are your differential diagnoses and how you would investigate this patient?

A

PDx: Wilm’s tumour
DDx: neuroblastoma, lymphoma

Primary survey and resus if necessary

Assessment

  • Confirm presentation: abdo pain, distension, mass, haematuria, fever, hypertension, cancer sx
  • Rule out differentials: neuroblastoma crosses the midline
  • U/S then CT abdo chest, CXR, bloods - FBC, EUC, coags (acquired vWD), CMP (Ca high in rhabdoid and congenital mesoblastic nephroma)

Management

  • surgical resection
  • staging (operative)
  • chemotherapy
  • radiotherapy if stage III and IV
  • supportive care: nutrition optimisation, ACEi for hypertension before resection, periop VWF/desmopressin if coagulopathic
84
Q

A 16 year old presents with a 2 week history of increasing breathlessness and a dry cough. He has lost 2kg in 1 month. On examination he has cervical lymphadenopathy, distended veins over the neck and face, hepatosplenomegaly and clinical signs suggestive of pleural effusion. Discuss his assessment and management.

A

PDx: lymphona
DDx:
other mediastinal tumour - thymoma, teratoma, lung cancer, metastasis
infection eg EBV

Primary survey and resus if necessary: protect airway
- (radiotherapy, SVC stenting, intubation are options if airway/cerebral circulation affected)

Assessment

  • characterise symptoms: cancer sx, haem cancer sx, lung cancer sx, other cancers (CNS, Wilm’s tumour, neuroblastoma, osteosarcoma and Ewing’s sarcoma)
  • examine haem, lungs, hepatosplenomegaly and then as per hx
  • FBC, CRP, UEC/CMP/LDH/uric acid (tumour lysis), lymph node biopsy

Management

  • stage: CXR, CT-PET chest abdo, LP
  • chemotherapy (including steroids because NHL is steroid-responsive)
  • monitor for tumour lysis