Paeds Flashcards

1
Q

how is congenital toxoplasmosis caused? What can it cause in the baby?

A

Congenital toxoplasmosis is due to transplacental spread from the mother.
The presence of chorioretinitis, intracranial calcifications, and hydrocephalus is considered the classic triad of congenital toxoplasmosis.
Some infected children without overt disease as neonates may escape serious sequelae of the infection; however, a significant number (14 to 85%) develop chorioretinitis, strabismus, blindness, hydrocephalus or microcephaly, cerebral calcifications, developmental delay, epilepsy, or deafness months or years later.

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2
Q

differentials for eye pain in children

A
Allergies
    Eye infection
    Eye inflammation
    conjunctivitis
    A foreign object in the eye
    Contact lens irritation
    An eye injury
    A stye
    blepharitis
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3
Q

differentials for transient altered vision in children

A

migraine (+/- aura)
occipital lobe epilepsy
psychogenic visual loss

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4
Q

what are the 2 broad types of seizures and give further examples and classifications of each.

A

Generalised – discharge arises from both hemispheres. They may be – absence, myoclonic, tonic, tonic-clonic and atonic
Focal – where seizures arise from one or part of one hemisphere. Consciousness may be retained or lost. Presentation -
Frontal seizures – involve the motor or premotor cortex. May lead to clonic movements, which may travel proximally (Jacksonian march). Asymmetrical tonic seizures can be seen, which may be bizarre and hyperkinetic and can be mistakenly dismissed as non-epileptic events. Atonic seizures may arise from mesial frontal discharge.
Temporal lobe seizures, the most common of all the epilepsies – may result in strange warning feelings or aura with smell and taste abnormalities and distortions of sound and shape. Lip-smacking, plucking at one’s clothing and walking in a non-purposeful manner (automatisms) may be seen, following spread to the pre-motor cortex. Déjà-vu and jamais-vu are described (intense feelings of having been, or never having been, in the same situation before). Consciousness can be impaired and the length of event is longer than a typical absence.
Occipital seizures – cause distortion of vision.
Parietal lobe seizures – cause contralateral dysaesthesias (altered sensation), or distorted body image.

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5
Q

What are the 4 fields of development?

A
  1. gross motor
  2. fine motor and vision
  3. hearing, speech and language
  4. social, emotional and behavioural
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6
Q

How should you adjust developmental milestones for prematurity?

A

Age correct up to 2 years of age

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7
Q

median age vs limit age with respect to developmental milestones?

A

The median age is the age when half of a standard
population of children achieve that level.
Limit ages are the age by which they should have
been achieved.

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8
Q

what is the limit age for walking unsupported?

A

18 months

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9
Q

by what action do most babies achieve mobility?

A

crawling.

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10
Q

in what order to crawlers, bottom shufflers and commando crawlers learn to walk unsupported?

A

The limit age of 18 months for walking applies predominantly to children who have had crawling as their early mobility pattern. Children who bottom
-shuffle or commando crawl tend to walk later than crawlers.

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11
Q

What are the primitive reflexes?

A
The primitive reflexes present at birth
gradually disappear as postural reflexes develop.
they are - 
Moro
grasp
rooting
stepping
asymmetric tonic neck reflex
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12
Q

When should the primitive reflexes have diminished by?

A

4-6 months

If they haven’t – could be a sign of cerebral palsy

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13
Q

limit age for head control?

A

4 months

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14
Q

limit age for sitting unsupported?

A

9 months

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15
Q

limit age for standing unsupported?

A

12 months

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16
Q

limit age for walking unsupported?

A

18 months

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17
Q

limit age for fixing and following visually

A

3 months

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18
Q

limit age for reaching for objects

A

6 months

19
Q

limit age for transferring objects

A

9 months

20
Q

limit age for pincer grip

A

12 months

21
Q

limit age for polysyllabic babble

A

7 months

22
Q

limit age for consonant babble

A

10 months

23
Q

limit age for saying 6 words with meaning

A

18 months

24
Q

limit age for joining words

A

2 years

25
Q

limit age for 3 word sentences

A

2.5 years

26
Q

limit age for smiling

A

8 weeks

27
Q

limit age for fear of strangers

A

10 months

28
Q

limit age for feeding self/using the spoon

A

18 months

29
Q

limit age for symbolic play

A

2-2.5 years

30
Q

limit age for interactive play

A

3-3.5 yrs

31
Q

At what age should a child be toilet trained during the day?

A

2 years

32
Q

When do children have their hearing checked?

A

Universal neonatal hearing screening
Hearing screening when they start school
If the parents are concerned about their hearing

33
Q

Up to which age is it normal to be able to see a squint in a child?

A

Newborns may appear to squint when looking at near objects

By 12 weeks – NO SQUINT should be present at all

34
Q

when are adult levels of visual acuity reached in children?

A

Visual acuity is poor in the newborn but

increases to adult levels by 4 years of age.

35
Q

when do all children in the UK get vision screening?

A

All children in the UK are screened for visual

acuity and squint at school entry.

36
Q

give some causes of abnormal development and learning difficulty

A

Genetic – chromosomal abnormalities, brain malformation
Congenital hypothyroidism
Teratogenic substances during pregnancy (including alcohol and drugs)
Infections during pregnancy
Hypoxic brain injury during birth
History of meningitis
Head trauma (accidental or non-accidental)
Brain hypoxia due to near-drowning, seizures
Unknown

37
Q

what is early onset sepsis

A

early-onset sepsis is sepsis <48 h after birth.

38
Q

what is late onset sepsis/infection?

A

late-onset infection is infection >48 h after birth. here birth), the source of infection is often the infant’s environment. The presentation is usually non-specific

39
Q

Inhaled foreign objects are most likely to be found in

A

right main bronchus (inferior lobe)

40
Q

encephalitis causes

A

This can be the result of infective or non-infective causes. Non-infective causes are autoimmune.
The most common cause is infection with a virus. Bacterial and fungal encephalitis is also possible although much more rare in the UK. The most common viral cause is herpes simplex virus (HSV). In children the most common cause is herpes simple type 1 (HSV-1) from cold sores. In neonates it is herpes simplex type 2 (HSV-2) from genital warts, contracted during birth. Other viral causes include varicella zoster virus (VZV) associated with chickenpox, cytomegalovirus associated with immunodeficiency, Epstein-Barr virus associated with infectious mononucleosis, enterovirus, adenovirus and influenza virus. It is important to ask about vaccinations, as the polio, mumps, rubella and measles viruses can cause encephalitis as well.

41
Q

presentation of encephalitis

A
Altered consciousness
    Altered cognition
    Unusual behaviour
    Acute onset of focal neurological symptoms
    Acute onset of focal seizures
    Fever
42
Q

ix for suspected encephalitis

A

Lumbar puncture, sending cerebrospinal fluid for viral PCR testing
CT scan if a lumbar puncture is contraindicated
MRI scan after the lumbar puncture to visualise the brain in detail
EEG recording can be helpful in mild or ambiguous symptoms but is not always routinely required
Swabs of other areas can help establish the causative organism, such as throat and vesicle swabs
HIV testing is recommended in all patients with encephalitis

Contraindications to a lumbar puncture include a GCS below 9, haemodynamically unstable, active seizures or post-ictal.

43
Q

mx of encephalitis

A

ntravenous antiviral medications are used to treat the suspected or confirmed underlying cause:

Aciclovir treats herpes simplex virus (HSV) and varicella zoster virus (VZV)
Ganciclovir treat cytomegalovirus (CMV)

Repeat lumbar puncture is usually performed to ensure successful treatment prior to stopping antivirals

Aciclovir is usually started empirically in suspected encephalitis until results are available. Other viral causes have no effective treatment and management is supportive.

Followup, support and rehabilitation is required after encephalitis, with help managing the complications.