Paediatric Oral Medicine Flashcards
What can cause oro-facial soft tissue infections?
- viral
- primary herpes
- herpangina
- hand, foot and mouth
- varicalla zoster
- bacterial
- staphylococcal
- streptococcal
- syphilis
- tuberculosis
- fungal
- candida
What is primary herpetic gingivostomatitis?
- acute infectious disease
- herpes simplex virus 1
- primary infection
- common in children
- recurrence as cold sores
- transmission by droplet formation
- 7 day incubation
- signs and symptoms
- fluid filled vesicles
- rupture to ulcers - severe oedematous marginal gingivitis
- fever
- headache
- malaise
- cervical lymphadenopathy
- fluid filled vesicles
- treatment
- usually self limiting after 14 days
- bed rest
- soft diet and hydration (dehydration most common cause)
- paracetamol
- antimicrobial gel or mouthwash
- acyclovir for immunocomprimised children
- virus remains dormant in epithelial cells
- recurrent as herpes labials in 50-75% of cases
- triggered by sunlight, stress or other causes of ill health
- managed by topical acyclovir cream
What does coxsackie A virus cause?
- herpangina
- hand, foot and mouth disease
What is herpangina?
- mild condition
- vesicles in the tonsils pharyngeal region
- similar to primary herpetic gingivalvostomatitis
- lasts 7-10 days
- management
- same as that of herpes simplex 1
What is hand foot and mouth disease?
- ulceration on the gingivae, tongue, palate and cheeks
- maculopapular rash on the hands and feet
- a couple of days after ulceration appears in mouth
- lasts 7-10 days
What is oral ulceration?
a localised defect in the surface oral mucosal where the covering epithelium is destroyed leaving an inflamed area of exposed connective tissue
What 10 key facts must be determined about an ulcer?
- onset
- frequency
- number
- site
- size
- duration
- exacerbating dietary factors
- lesions in other areas
- associated medical problems
- treatment attempt so far (success?)
What infections can cause oral ulceration?
- viral
- hand, foot and mouth
- herpes simplex
- herpez zoster
- bacterial
- tuberculosis
- syphilis
What immune mediated disorders can cause oral ulceration?
- Crohns
- behcets
- SLE
- coeliac
What vesticulobullous disorders can cause oral ulceration?
- bulbous or mucous membrane pemphigoid
- pemphigus
- pemphigus vulgaris
- linear IgA disease
What are the potential causes of oral ulceration?
- infection
- immune mediated disorders
- vesticulobullous disorders
- inherited or acquired immunodeficiency disorders
- neoplastic/haemotalogical
- trauma
- vitamin deficiencies
- recurrent apthous stomatitis
What neoplastic/haemotalogical factors can cause oral ulceration?
- anaemia
- leukaemia
- agranulocytosis
- cyclic neutropenia
What vitamin deficiencies can cause oral ulceration?
- iron
- B12
- folate
What is recurrent pathos ulceration?
- most common cause of ulceration in children
- round or ovoid shaped ulcers
- grey or yellow base
- varying degree of perilesional erythema
- 3 patterns
- minor (<10mm), 10-14 days to heal, only unkeratinised
- major (>10mm), several weeks to heal, also keratinised
- herpetiform (1-2mm), many ulcers at a time
- aetiological factors
- hereditary predisposition
- haemotalogical and deficiency disorders
- GI disease
- minor trauma in susceptible individuals
- stress
- allergic disorders
- hormonal disturbance
- investigations
- diet diary
- FBC
- haematinics
- coeliac screen
- management
- avoid exacerbating food groups
- supplementation
- pharmacological
- corsodyl 0.2% mouthwash (infection prevention)
- gengigel topical gel, gelclair mouthwash (protection)
- difflam, LA spray (symptomatic relief)
What is orofacial granulomatosis?
- uncommon chronic inflammatory disorder
- associated with systemic granulomatous conditions
- Crohns
- sarcoidosis - average onset at 11 years old
- associated with systemic granulomatous conditions
- non caseating giant cell granulomas
- result in lymphatic obstruction
- can be predictor of future Crohns
- clinical features
- lip swelling
- full thickness gingival swelling
- swelling of other facial tissues
- peri-oral erythema
- cobblestone appearance buccal mucosa
- linear ulceration
- mucosal tags
- lip/tongue fissuring
- angular chelitis
- aetiology
- largely unknown
- potentially genetic
- associated allergens
- cinnamon compounds
- benzoates - higher IgE mediated atopy rates
- diagnosis
- clinical, lip biopsy not essential
- measure facial growth
- FBC
- haematinics
- patch testing to identify triggers
- diet diary to identify triggers
- faecal calprotectin
- management
- oral hygiene support
- symptomatic relief for ulceration
- dietary exclusion
- management of nutritional deficiencies
- topical steroids
- topical tacrolimus
- short course of oral steroids
- intralesional steroids
- surgical intervention
What is geographic tongue?
- shiny red areas on tongue with loss of filiform papillae surrounded by white margins, migrating over tongue
- benign but can be painful
What solid swellings can be seen in the mouth?
- fibroepithelial polyp
- epulides
- congenital epulis
- HPV-associated mucosal swellings
- neurofibromas
What are fibroepithelial polyps?
- firm pink lumps
- pedunculate or sessile
- benign
- mostly found in commonly traumatised areas
- managed by surgical excision under LA
What are epulides?
- common solid swellings over the oral mucosa
- benign hyperplastic lesions
- inter proximal dental tissues most common
- related to chronic dental irritation (calculus and plaque)
- majority anterior to molars, mostly in maxilla
- 3 main types
- fibrous epulis
- pedunculate or sessile mass
- firm consistency
- similar colour to surrounding gingival
- inflammatory cell infiltrate and fibrous tissue - pyogenic granuloma
- soft, deep, red/pruple swelling
- often ulcerated
- haemorrhage spontaneously or with mild trauma
- vascular proliferation supported by fibrous stroma
- reaction to chronic trauma
- tend to recur after removal - peripheral giant cell granuloma
- pedunculate or sessile swelling
- typically dark red and ulcerated
- interproximally with hourglass shape
- superficial erosion of interdental bone
- multinucleate giant cells in vascular stroma
- may recur after surgical excision
- fibrous epulis
- managed by surgical excision and removal of exacerbating factors
- commonly recur
What are congenital epulis?
- rare lesion occurring in neonates
- most common in anterior maxilla
- granular cells covered with epithelium
- benign
- simple surgical excision
- does not recur
What are HPV associated swellings
- verruca vulgaris
- HPV 2 and 4
- solitary or multiple lesions
- keratinised tissue most commonly affected
- spontaneous resolution or surgical removal
- squamous cell papilloma
- HPV 6 and 11
- small pedunculate cauliflower like growths
- benign
- white-pink in colour
- usually solitary
- surgical excision
What fluid filled swelling can be seen in the mouth?
- mucoceles
- radula
- Bohn’s nodules
- Epstein pearls
- haemangiomas
- vesiculobullous lesions
- primery herpes
- epidermolysis bulls
- erythema multiforme
What are mucoceles?
- 2 variants
- mucous extravasions cyst
- normal secretions rupture into adjacent tissues - mucous retention cyst
- secretions retained in an expanded duct
- mucous extravasions cyst
- blush, soft, transparent, cystic swelling
- affect minor or major salivary glands
- most affect minor glands of the lower lip
- most rupture spontaneously
- surgery only if lesion fixed in size
- will likely damage adjacent gland
- leads to recurrence
- removal of cyst and adjacent damaged minor salivary gland
What are ranula?
- mucocele in the floor of the mouth
- minor salivary glands or ducts or sublingual/submandibular
- ultrasound or MRI needed to exclude plunging radula
- extended into submittal or submandibular space
- occasionally found to be lymphangioma
- benign tumour of the lymphatics
What are Bohn’s nodules?
- gingival cysts
- remnants of the dental lamina
- filled with keratin
- occur on alveolar ridge
- found in neonates
- first 28 days
- disappear in early months of life
What are Epstein pearls?
- small cystic lesions
- found along palatal midline
- trapped epithelium in palatal raphe
- in around 80% of neonates
- disappear in first few weeks
What is temporomandibular joint dysfunction syndrome?
- most common condition affecting the temporomandibular region
- characterised by:
- pain
- masticatory muscle spasm
- limited jaw opening
- history
- presenting symptoms
- when discomfort started
- exacerbating factors
- habits
- stress
- examination
- palpation of muscles of mastication
- at rest and on clenching
- assess tenderness or hypertrophy - palpation of TMJ
- at rest
- when opening and closing
- assess tenderness and click/crepitus - assessment of opening
- check for deviation of jaw
- assess extent of opening - intraoral
- assessment of dental wear facets
- signs of clenching or grinding
- scalloped lateral tongue surface
- buccal mucosa ridges
- palpation of muscles of mastication
- symptomatic relief
- ibuprofen
- alternating use of hot and cold packs