Paediatric fluids Flashcards

1
Q

Fluid of choice:

a) Neonate
b) Maintenance in children
c) Fluid bolus for shock
d) Ongoing losses

A

a) 10% glucose
b) 0.9% NaCl + 5% glucose
c) 0.9% NaCl
d) 0.9% NaCl + potassium (K+)

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2
Q

Neonates - amount each day

A

Day 1 - 60ml/kg
Day 2 - 90ml/kg
Day 3 - 120ml/kg
Day 4 - 150ml/kg

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3
Q

Add what ratios from day 2 in neonate

A

Na (3), K (2), Ca (1)

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4
Q

Children: calculating maintenance fluid volumes

a) Per day
b) Per hour
c) Approximate weight calculation formula

A

a) Per day.
(100 x 1st 10kg) + (50 x 2nd 10kg) + (20 x remaining kg)

b) Per hour.
(4 x 1st 10kg) + (2 x 2nd 10kg) + (1 x remaining kg)

c) Weight (kg) = (age + 4) x 2

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5
Q

Hydration status (NICE).

a) Normal
b) Mild-moderate (< 10%) dehydration)
c) Red flags (STAT, STAT)
d) 3 most sensitive indicators of 5% dehydration (abnormal … mnemonic: CRT)

A

a)
b) Restlessness or irritability. Sunken eyes (also ask the parent). Thirsty and drinks eagerly
c) Sunken eyes (sunken fontanelle in infants), Tachypnoea, Appears unwell, Tachycardia. Skin mottled/pale, Turgor reduced, Altered responsiveness (e.g, irritable, lethargic), Thready peripheral pulses
d) Cap refill time, Respiratory pattern, Turgor (skin)

Note: hypotension is a very late sign

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6
Q

Correction of fluid deficits.

a) Equation (for excess fluid per 24h_
b) So if they are 5% dehydrated
c) Shock (10%)
d) Three indications for IV over oral fluid replacement

A

a) (Weight) x (% dehydration) x 10
= additional fluid requirement over 24h

b) 5 x 10 = 50mls/kg extra per 24h
c) Fluid bolus + 100mls/kg extra per 24h
d) Shock, red flags for severe dehydration, unable to tolerate/hold down oral fluids (e.g. pyloric stenosis)

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7
Q

Fluid bolus for shock

When would you give reduced dosage (e.g. 10mls/kg)?

A

20 mls/kg 0.9% sodium chloride

DKA, trauma, head injury, NEONATES, heart failure

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8
Q

DKA.

a) 3 biochemical findings to diagnose
b) ABCD of management in DKA
c) IV ____ and _____ replacement; then 1-2 hours later administer IV _____.
d) When glucose falls to 12-15mmol/L, switch fluids to…?
e) Why are serum potassium levels misleading in DKA?
f) Causes of death in DKA

A

a) Glucose > 11 mmol/L; Venous pH < 7.3 or HCO3- < 15 mmol/L; ketonaemia and ketonuria
b) Assess GCS, administer 100% oxygen, insert IV cannulae and give fluids (10ml/kg NaCl 0.9% bolus), reassess GCS
c) Fluids and potassium; insulin
d) NaCl and 5% glucose
e)
f) Cerebral oedema

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9
Q

Causes of dehydration.

a) 4 pathophysiological causes
b) Common causes: i) GI, ii) Endocrine, iii) Oropharyngeal, iv) Other

A

a) Reduced intake, increased output (renal, gastrointestinal or insensible losses), transcellular shift (ascties, effusions), capillary leakage (burns, inflammation, sepsis)

b) i) Diarrhoea, bowel obstruction, pyloric stenosis,
ii) DKA, DI, thyrotoxicosis, CAH,
iii) Ulcers, pharyngitis, etc (may limit intake),
iv) Febrile illness, CF, burns, heat stroke

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10
Q

Insensible fluid losses - define

A

The amount of fluid lost on a daily basis from the lungs, skin, respiratory tract, and water excreted in the faeces

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11
Q

Monitoring during fluid replacement.

a) General
b) Infant - assess tension of the _______.
c) What indicates good response to fluids?

A

a) well-being, pulse rate and volume, capillary refill, blood pressure, urine output (via catheter) ECG monitoring, and blood renal function, electrolytes.
b) Fontanelle

c) Slowing of the heart rate (to the normal range for the child's age). Improved conscious state and awareness.
Return of peripheral pulses, return of normal skin colour and increased warmth of extremities.
Increased SBP (approximately 90 mm Hg plus twice the age in years), increased pulse pressure (above 20 mm Hg). Normalising of urine output for age
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12
Q

Normal urine output by age

A

Newborn/infant: 2 ml/kg/hour
Toddler: 1.5 ml/kg/hour
Older child: 1 ml/kg/hour
Adult: 0.5 ml/kg/hour

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13
Q

Oral rehydration (Dioralyte)

a) Prescribe after each large, watery stool in what 4 high risk groups/ clinical scenarios?
b) Dose (ml/kg)

A

a) Children younger than 1 year, particularly those younger than 6 months.
Infants who were of low birth weight.
Children who have passed more than five diarrhoeal stools in the previous 24 hours.
Children who have vomited more than twice in the previous 24 hours

b) 5 ml/kg

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14
Q

DKA presentation

a) May be the first…?
b) Common symptoms
c) Common signs

A

a) presentation of T1DM
b) Lethargy, confusion. Polyuria ± polydypsia. Weight loss. Abdominal pain ± vomiting (may mimic a surgical abdomen).

c) Dehydration. Rapid, deep sighing (Kussmaul’s respirations). Ketotic breath - fruity, pear drops smell.
Shock, coma (assess Glasgow Coma Scale). Evidence of cerebral oedema, or infection.

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15
Q

Metabolic acidosis.

a) Anion gap calculation and normal value
b) Causes of high anion gap metabolic acidosis (MUDPILES)
c) 2 causes of normal anion gap metabolic acidosis

A

a) ([Na+] + [K+]) − ([Cl−] − [HCO3−]) = 20 mEq/L

b) Methanol, Uraemia (chronic kidney failure), Diabetic ketoacidosis, Paracetamol, Infection, Iron, Isoniazid, Inborn errors of metabolism, Lactic acidosis, Ethanol, Salicylates
c) Diarrhoea, RTA

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16
Q

Collapsed neonate: 4 most likely causes

A

Sepsis, Congenital HD, Metabolic, NAI

17
Q

Cyanotic HD mnemonic:
Mnemonic: 1, 2, 3, 4, 5

Tetralogy patients may get symptoms relief when they _____.

A
1 - truncus arteriosus
2 - transposition
3 - tricuspid atresia
4 - tetralogy of fallot
5 - total anomalous pulmonary venous return

Squat - increases systemic venous return to reduce VSD shunting

18
Q

Paediatric GCS

A
Verbal:
Coos, babbles+5
Irritable cries+4
Cries in response to pain+3
Moans in response to pain+2
No response +1
Motor: 
Moves spontaneously/purposefully+6
Withdraws to touch+5
Withdraws to pain+4
Flexor posturing to pain+3
Extensor posturing to pain+2
No response +1
19
Q

WET FLAG.

For a collapsed infant/child: relevant drugs, equipment and things to remember

A

Weight = (age+4) x 2
Energy = 4 x weight (J) – this is the energy required for defibrillation
Tube = age/4 + 4 (approx size of endotracheal tube uncuffed for intubation)
Fluids = 20ml/kg of N/Saline bolus (10ml/kg for trauma/DKA/heart failure)
Lorazepam
Adrenaline = 10mcg/kg
Glucose = 2ml/kg of 10% glucose

20
Q

4 Ts and 4 Hs of reversible cardiac arrest

A

Hypoxia (low levels of oxygen)
Hypovolemia (shock)
Hyperkalemia/hypokalemia/hypoglycemia/hypocalcemia (+ other metabolic disturbances)

Hypothermia
Thrombosis (coronary or pulmonary)
Tension pneumothorax
Tamponade (cardiac)
Toxins
21
Q

History of fluid loss.

a) Neonates
b) Children

A

a) Feeds (type, volume, frequency), wet nappies (at least 3 per day), vomiting (esp. bilious), skin changes (jaundice, mottled), floppy, lethargic, FTT
b) Normal eating and drinking, weight loss, diarrhoea, vomiting

22
Q

2 year old girl admitted to resus following diarrhoea and vomiting, with prolonged CRT and estimated 8% dehydration. Na 140, K 3.1, glucose 5.2

a) Calculate approximate weight based on age
b) What is your immediate management?
c) What should her maintenance fluids be? (type + volume)

A

a) (Age + 4) x 2
= 12 kg

b) Fluid bolus of NaCl 0.9% 20ml/kg
= 20 x 12
= 240 mL

c) Type: NaCl 0.45%/Dex 5% + KCl (due to low K)

12kg.
(100 x 10) + (50 x 2) = 1100 mL per day

-Dehydration deficit correction (per 24h):
= % dehydration x weight x 10
= 8 x 12 x 10 = 960 mL per day

Maintenance = 1100 + 960 = 2060 mL per day
= 85ml/hr

23
Q

Blood gases.

a) Acidosis + high CO2 - causes in children
b) Acidosis + low CO2 - causes in children
c) Alkalosis + high CO2 - causes in children
d) Alkalosis + low CO2 - causes in children

A

a) Resp acidosis
- severe asthma, pneumonia, hypoventilation

b) Met acidosis (resp compensation; low HCO3-)
- DKA (Kussmaul breathing), lactic acidosis (sepsis), salicylate poisoning

c) Met alkalosis (resp compensation; raised HCO3-)
- severe vomiting, diarrhoea, potassium diuresis

d) Resp alkalosis
- hyperventilation

24
Q

Why some hypercapnia / acidosis is permissive in neonates (especially preterm)

A

Low CO2 (HYPOcapnia) is bad for cerebral blood flow and can cause lung injury

25
Q

Anion gap.

a) Equation
b) Normal range
c) Other things that can affect anion gap
d) Causes of high anion gap metabolic acidosis
e) Causes of normal anion gap metabolic acidosis

A

a) (Na + K) - (HCO3 + Cl)
b) 3 - 11 mmol/L
c)
d) Lactic acidosis, DKA
e) Gastrointestinal loss and renal tubular acidosis