Paediatric Drugs

Question 1

What is the dose of adrenaline in a cardiac arrest situation?

Answer 1

10 mcg/kg = 0.1 ml/kg of 1:10,000 solution

Question 2

Dose of promethazine.

Answer 2

1 mg/kg (max 25 mg) PO or slow IV push (causes hypotension)

Question 3

Adrenaline bolus in anaphylaxis:

Answer 3

10 mcg/kg IM

= 0.01 ml/kg of 1:1000 solution or 0.1 ml/kg of 1:10,000 solution

Question 4

What is the dose of amoxycillin in paeds?

Answer 4

50 mg/kg QID (max 2 grams)

Indication: neonatal sepsis

Question 5

What is the dose of cefotaxime in paeds?

Answer 5

50 mg/kg TDS (max 2 grams)

Indication: neonatal sepsis

Question 6

What is the dose of ceftriaxone in paeds?

Answer 6

50 mg/kg daily (max 2 grams).

Indications: meningitis, severe sepsis in infants >6/52

Question 7

What is the dose of gentamicin in paeds?

Answer 7

7.5 mg/kg

Indication: neonatal sepsis

Question 8

What is the dose of benzylpenicillin in paeds?

Answer 8

30 mg/kg (max 1.2 grams) QID in LRTI in paeds

Question 9

What is the dose of azithromycin in paeds?

Answer 9

10 mg/kg (500 mg) daily

Question 10

What is the dose of roxithromycin in paeds?

Answer 10

4 mg/kg (max 150 mg) BD

Question 11

What is the dosing for vancomycin in paeds?

Answer 11

30 mg/kg (1.5 grams) BD. Staph sepsis.

Question 12

What is the dosing for meropenem in paeds?

Answer 12

25 mg/kg (1 gram) in meliodosis

Question 13

What is the dose of hypertonic saline and mannitol in paeds head injury?

Answer 13

Mannitol: 0.25-0.5 g/kg over 20-30 minutes IV

Hypertonic saline: sodium chloride 3%, 3 ml/kg over 10-20 minutes IV

Question 14

What is the loading dose of phenytoin in paeds?

Answer 14

15-20 mg/kg IV

Question 15

What is the seizure-dose of midazolam in paeds?

Answer 15

0.15 mg/kg IV