paces Flashcards
define endometriosis
endomtrial glands and stroma forming outside of the endometrial cavity - found in extrauterine locations
- this bleeds > scars > pain and adhesions
halban
distant lesions are established by the hematogenous or lymphogenous spread of viable endometrial cells
what ectopic locations can endometrial glands and stroma present in?
in endometriosis
pelvic peritoneum
ovaries
rectovaginal
stigmata of endometriosis?
dysmenorrhea
dyspareunia
chronic pelvic pain
irregular uterine bleed
infertility
theory of retrograde mestruation is by?
sampson theory
what type of pain occurs in endometriosis?
painful menstrual cramps
chronic long term pain in lower back and pelvis
pain during sex - deep pain
intestinal pain
why does endometriosis cause pain?
endometrial growths outside of uterine cavity grow and swell and bleed in a similar way
but when it bleed - where does it go?
trapped blood in overis = cysts
inflammation
scar tissue and adhesions - pelvic pain
problems in your intestines and bladder
theories of endometriosis
problems with menstrual period flow
genetic factors
immune system problems
hormones
surgery
managing endometriosis?
conservative - pain relief; paracetamol / nsaids
medical management focuses on suppressing oestrogen production thus inhibiting the endometrial growth; contraceptive
surgical options
role of GnRH anologues in endometriosis
GnRH - helps to control menstrual cycle as it stops produtcion of oestrogen
starving endometriosis of oestrogen causes the deposits to become inactive and reduce
example : goserelin
buserelin