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Pharmocolgy > P6: Drugs and the Sympathetic Nervous System > Flashcards

P6: Drugs and the Sympathetic Nervous System Flashcards

1
Q

What receptor subtypes do selective direct acting sympathomimetics act on

A

alpha 1 and 2

beta 1 and 2

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2
Q

What receptor subtypes do non- selective direct acting sympathomimetics act on

A

alpha 2

beta 2

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3
Q

What are the modes of action for indirect acting sympathomimetics

A
  • cause the release of stored catecholamines (CAs)
  • inhibit reuptake of CAs by nerve terminals
  • increase transmitter presence/longevity in synapse
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4
Q

What are the main catecholamines

A

Epinephrine(adrenaline
Norepinephrine(noradrenaline)
Dopamine

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5
Q

What gland releases CAs and why

A

Adrenal glands release lots of CAs in response to stress

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Pharmocolgy (22 decks)

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