P450 Interactions Flashcards

1
Q

Phenytoin

inducer, substrate, inhibitor

A

induces P450

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2
Q

Ritonavir

inducer, substrate, inhibitor

A

inhibits P450

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3
Q

Rifampin

inducer, substrate, inhibitor

A

induces P450

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4
Q

Amiodarone

inducer, substrate, inhibitor

A

inhibits P450

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5
Q

Macrolides (except Azithromycin)

inducer, substrate, inhibitor

A

inhibits P450

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6
Q

Griseofulvin

inducer, substrate, inhibitor

A

induces P450

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7
Q

mnemonic for inducers of P450

A

CHRONIC ALCOHOLics STeal PHEN-PHEN and Never Refuse Greasy CARBs

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8
Q

St. John’s Wart

inducer, substrate, inhibitor

A

induces P450

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9
Q

Acute Alcohol Abuse

inducer, substrate, inhibitor

A

inhibits P450

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10
Q

Warfarin

inducer, substrate, inhibitor

A

substrate of P450

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11
Q

Chronic Alcohol use

inducer, substrate, inhibitor

A

induces P450

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12
Q

mnemonic for Inhibitors of P450

A

AAA RACKS IN GQ Magazine

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13
Q

Nevirapine

inducer, substrate, inhibitor

A

induces P450

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14
Q

Isoniazid (INH)

inducer, substrate, inhibitor

A

inhibits P450

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15
Q

Cimetidine/Ciprofloxacin

inducer, substrate, inhibitor

A

inhibits P450

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16
Q

mnemonic for Substrates of P450

A

Always Think When Outdoors

17
Q

Theophylline

inducer, substrate, inhibitor

A

substrate of P450

18
Q

Ketoconazole

inducer, substrate, inhibitor

A

inhibits P450

19
Q

Grapefruit Juice

inducer, substrate, inhibitor

A

inhibits P450

20
Q

Carbamazepine

inducer, substrate, inhibitor

A

induces P450

21
Q

Phenobarbital

inducer, substrate, inhibitor

A

induces P450

22
Q

OCP

inducer, substrate, inhibitor

A

substrate of P450

23
Q

Anti-epileptics

inducer, substrate, inhibitor

A

substrate of P450

24
Q

Quinidine

inducer, substrate, inhibitor

A

inhibits P450

25
Q

Sulfonamides

inducer, substrate, inhibitor

A

inhibits P450