P450 Drugs Bisnitch Flashcards
1
Q
What CYP are caffeine and theophylline metabolized by?
A
CYP1A2
2
Q
What CYP are phenytoin and (s)-warfarin metabolized by?
A
CYP2C9
3
Q
What CYP is Diazepam metabolized by?
A
CYP2C19
4
Q
What CYP is Codeine metabolized by?
A
CYP2D6
5
Q
What CYP is paracetamol (tylenol) metabolized by?
A
CYP2E1
6
Q
What CYP are terdenadine and verapamil metabolized by?
A
CYP3A4
7
Q
What is an inducer of CYP1A2?
A
Smoking and charred food
8
Q
What is an inducer of CYP2C9?
A
rifampicin
9
Q
What is an inducer of CYP2C19?
A
St. Johns Wort
10
Q
What is an inducer of CYP2D6?
A
Rifampin
11
Q
What is an inducer of CYP3A4?
A
St. Johns Wort
12
Q
What is an inhibitor of CYP1A2?
A
Grapefruit Juice
13
Q
What is an inhibitor of CYP2C9?
A
Macrolides
14
Q
What is an inhibitor of CYP2C19?
A
Fluoxetine
15
Q
What is are 2 inhibitors of CYP2D6?
A
Quinidine and haloperidol
